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Protein
Submitted name:

Cystic fibrosis transmembrane conductance regulator

Gene

CFTR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cystic fibrosis transmembrane conductance regulatorImported
Gene namesi
Name:CFTRImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiQ6KEB2.

Family & Domainsi

Keywords - Domaini

TransmembraneImported

Family and domain databases

InterProiIPR009147. CFTR/ABCC7.
[Graphical view]
PANTHERiPTHR24223:SF19. PTHR24223:SF19. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q6KEB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30
KVFIFSGTFR KNLDPYEQWS DQEIWKVADE
Length:30
Mass (Da):3,677
Last modified:July 5, 2004 - v1
Checksum:i42952348009026CD
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei30 – 301Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ575034 Genomic DNA. Translation: CAE00748.1.
AJ575035 Genomic DNA. Translation: CAE00749.1.
AJ575036 Genomic DNA. Translation: CAE00750.1.
AJ575037 Genomic DNA. Translation: CAE00751.1.
AJ575038 Genomic DNA. Translation: CAE00752.1.
AJ575039 Genomic DNA. Translation: CAE00753.1.
AJ575040 Genomic DNA. Translation: CAE00754.1.
UniGeneiHs.489786.
Hs.621460.
Hs.661104.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ575034 Genomic DNA. Translation: CAE00748.1.
AJ575035 Genomic DNA. Translation: CAE00749.1.
AJ575036 Genomic DNA. Translation: CAE00750.1.
AJ575037 Genomic DNA. Translation: CAE00751.1.
AJ575038 Genomic DNA. Translation: CAE00752.1.
AJ575039 Genomic DNA. Translation: CAE00753.1.
AJ575040 Genomic DNA. Translation: CAE00754.1.
UniGeneiHs.489786.
Hs.621460.
Hs.661104.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Gene expression databases

BgeeiQ6KEB2.

Family and domain databases

InterProiIPR009147. CFTR/ABCC7.
[Graphical view]
PANTHERiPTHR24223:SF19. PTHR24223:SF19. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "An engineered genomic CFTR construct is expressed and correctly spliced in the human lung sarcoma cell line HT1080."
    Schindelhauer D., Laner A., Cattani S., Christan S., Ramalho A.S., Marques B., Beck S., Penque D., Amaral M.D.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6KEB2_HUMAN
AccessioniPrimary (citable) accession number: Q6KEB2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 27, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.