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Protein
Submitted name:

Cystic fibrosis transmembrane conductance regulator

Gene

CFTR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
Cystic fibrosis transmembrane conductance regulatorImported
Gene namesi
Name:CFTRImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiQ6KE95.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000003084.

Family & Domainsi

Keywords - Domaini

TransmembraneImported

Sequencei

Sequence statusi: Fragment.

Q6KE95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VIEENKVRQY DSIQKLLNER SLFRQAISPS DRVKLFPHRN SSKCKSKPQI
60
AALKEETEEE VQDTRL
Length:66
Mass (Da):7,756
Last modified:July 5, 2004 - v1
Checksum:i61768A3524F10285
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ575051 Genomic DNA. Translation: CAE00765.1.
AJ575052 Genomic DNA. Translation: CAE00766.1.
AJ575053 Genomic DNA. Translation: CAE00767.1.
AJ575054 Genomic DNA. Translation: CAE00768.1.
AJ575055 Genomic DNA. Translation: CAE00769.1.
UniGeneiHs.489786.
Hs.621460.
Hs.661104.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ575051 Genomic DNA. Translation: CAE00765.1.
AJ575052 Genomic DNA. Translation: CAE00766.1.
AJ575053 Genomic DNA. Translation: CAE00767.1.
AJ575054 Genomic DNA. Translation: CAE00768.1.
AJ575055 Genomic DNA. Translation: CAE00769.1.
UniGeneiHs.489786.
Hs.621460.
Hs.661104.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000003084.

Chemistry

BindingDBiQ6KE95.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Gene expression databases

BgeeiQ6KE95.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "An engineered genomic CFTR construct is expressed and correctly spliced in the human lung sarcoma cell line HT1080."
    Schindelhauer D., Laner A., Cattani S., Christan S., Ramalho A.S., Marques B., Beck S., Penque D., Amaral M.D.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6KE95_HUMAN
AccessioniPrimary (citable) accession number: Q6KE95
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: June 24, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.