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Protein
Submitted name:

Alpha-2,8-sialyltransferase ST8Sia IV

Gene

st8sia4

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity Source: ZFIN
  • sialyltransferase activity Source: ZFIN

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseSAAS annotationImported, Transferase

Enzyme and pathway databases

ReactomeiR-DRE-4085001. Sialic acid metabolism.
R-DRE-419037. NCAM1 interactions.

Protein family/group databases

CAZyiGT29. Glycosyltransferase Family 29.

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-2,8-sialyltransferase ST8Sia IVImported (EC:2.4.99.8Imported)
Submitted name:
N-glycan alpha 2,8-sialyltransferaseImported
Submitted name:
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4Imported
Gene namesi
Name:st8sia4Imported
Synonyms:pstImported, siat 8DImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 10

Organism-specific databases

ZFINiZDB-GENE-060322-10. st8sia4.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatusSAAS annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_501121046527 – 358Sequence analysisAdd BLAST332

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi141 ↔ 291UniRule annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000103600.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000011180.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 29 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG2692. Eukaryota.
ENOG410XT8P. LUCA.
GeneTreeiENSGT00550000074407.
HOGENOMiHOG000232070.
HOVERGENiHBG056466.
OMAiHSVEGWK.
OrthoDBiEOG091G0AL4.
TreeFamiTF352820.

Family and domain databases

InterProiView protein in InterPro
IPR001675. Glyco_trans_29.
IPR012163. Sialyl_trans.
PfamiView protein in Pfam
PF00777. Glyco_transf_29. 1 hit.
PIRSFiPIRSF005557. Sialyl_trans. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q6KC03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLSRKHWTV CTISVLLVLF YKTTDIGRNE VHQKASLTWY LEPSATRLMA
60 70 80 90 100
NGSEKLFGNV LNGLDLGVGW KINATLVSII RKDILRYLDA ERDVSVIKSN
110 120 130 140 150
FKPGDTIRYV LDRRRTFSVS QTLHSLLPEV SPLKNKTFKT CAVVGNSGIL
160 170 180 190 200
LKSGCGKEID NHSFVIRCNL APLEGFADDV GLRSDFTTMN PSVIQRVYGG
210 220 230 240 250
LREETQQENL IQRLRQLNDS VLWIPAFMVK GGMKHVDTVN ELILKHKLKV
260 270 280 290 300
RTAYPSLRLI HAVRGFWLTN KINIKRPTTG LLMYTMATRF CDEIYLYGFW
310 320 330 340 350
PFPKDASGNP VQYHYFDGLK YRYFSNAGPH RMPLEFQTLQ RLHSKGALKL

TTSKCTST
Length:358
Mass (Da):40,837
Last modified:July 5, 2004 - v1
Checksum:iD720FB85BEF4872B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei358Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX294128 Genomic DNA. No translation available.
CU896666 Genomic DNA. No translation available.
DQ779599 mRNA. Translation: ABG77976.1.
AJ715545 mRNA. Translation: CAG29384.1.
RefSeqiNP_001092886.1. NM_001099416.1.
UniGeneiDr.91772.

Genome annotation databases

EnsembliENSDART00000157776; ENSDARP00000135219; ENSDARG00000103600.
ENSDART00000170062; ENSDARP00000131324; ENSDARG00000103600.
GeneIDi553211.

Similar proteinsi

Entry informationi

Entry nameiQ6KC03_DANRE
AccessioniPrimary (citable) accession number: Q6KC03
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 22, 2017
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported