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Protein

Polyribonucleotide nucleotidyltransferase 2, mitochondrial

Gene

PNP2

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in the 3'-end maturation of mitochondrial mRNAs, rRNAs and tRNAs. Functions as a poly(A) mRNA 3'-5' degrading phosphorylase (By similarity).By similarity

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, RNA-binding, Transferase
Biological processmRNA processing, rRNA processing, tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferase 2, mitochondrial (EC:2.7.7.8)
Alternative name(s):
Polynucleotide phosphorylase 2
Short name:
PNPase 2
Gene namesi
Name:PNP2
Ordered Locus Names:Os02g0617700, LOC_Os02g40460
ORF Names:OJ1014_H03.14
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 39MitochondrionSequence analysisAdd BLAST39
ChainiPRO_000042027740 – 982Polyribonucleotide nucleotidyltransferase 2, mitochondrialAdd BLAST943

Proteomic databases

PaxDbiQ6KAI0
PRIDEiQ6KAI0

Expressioni

Gene expression databases

ExpressionAtlasiQ6KAI0 differential
GenevisibleiQ6KAI0 OS

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os02g40460.1

Structurei

3D structure databases

ProteinModelPortaliQ6KAI0
SMRiQ6KAI0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini624 – 678KHAdd BLAST55
Domaini689 – 757S1 motif 1Add BLAST69
Domaini920 – 982S1 motif 2Add BLAST63

Sequence similaritiesi

Keywords - Domaini

Repeat, Transit peptide

Phylogenomic databases

eggNOGiKOG1067 Eukaryota
COG1185 LUCA
InParanoidiQ6KAI0
OrthoDBiEOG0936088V

Family and domain databases

Gene3Di3.30.230.70, 2 hits
HAMAPiMF_01595 PNPase, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR015847 ExoRNase_PH_dom2
IPR036345 ExoRNase_PH_dom2_sf
IPR012340 NA-bd_OB-fold
IPR012162 PNPase
IPR027408 PNPase/RNase_PH_dom_sf
IPR015848 PNPase_PH_RNA-bd_bac/org-type
IPR036456 PNPase_PH_RNA-bd_sf
IPR020568 Ribosomal_S5_D2-typ_fold
IPR022967 S1_dom
IPR003029 S1_domain
PANTHERiPTHR11252 PTHR11252, 2 hits
PfamiView protein in Pfam
PF03726 PNPase, 1 hit
PF01138 RNase_PH, 2 hits
PF03725 RNase_PH_C, 1 hit
PF00575 S1, 1 hit
SMARTiView protein in SMART
SM00316 S1, 2 hits
SUPFAMiSSF46915 SSF46915, 1 hit
SSF50249 SSF50249, 2 hits
SSF54211 SSF54211, 2 hits
SSF55666 SSF55666, 2 hits
TIGRFAMsiTIGR03591 polynuc_phos, 1 hit
PROSITEiView protein in PROSITE
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6KAI0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSMAVASLRL LARGGRRRAR FPAPLSVPGG RAAFLSGAAE EVAQADAPPP
60 70 80 90 100
PPPGRKVLES FREEFEIGGR VISFETGKMA RFANGSVVIS MDDTHVLSTV
110 120 130 140 150
AAAKSSEPVR DFLPLTVDYQ EKQYAQGVIP TTYMRREGAP KERELLCGRI
160 170 180 190 200
IDRPIRPLFP PGFYHEVQVM NATIIMVNVI SSDGKQDPDV MAANASSAAL
210 220 230 240 250
MLSDIPWNGP IGVIRVGRID GNFVLNPTVD ELGLSDLNLV YACSRDKTLM
260 270 280 290 300
IDVQAREITE RDLQAGMKLA HAEAVKCINP QLRLAKRAGK KKKEYKISLI
310 320 330 340 350
SDKSYEKIRT LSEAPIEEVF TDSTYGKFER GEALENITQS VKAKLEEECD
360 370 380 390 400
EDSLKFLHKA VDTVRKQVIR KRIIEKGLRV DGRQLDEVRP LYCESSTYPI
410 420 430 440 450
LHGSALFSRG DTQVLCTVTL GAPGDAQRLD SIVGPPTKRF MLHYSFPPFS
460 470 480 490 500
INEVAKRGGL NRREVGHGTL AEKALLAVLP PEGEFPYTVR VNSEVMASDG
510 520 530 540 550
STSMASVCGG SMALMDAGIP VREHVAGVSV GLVSEVDQTT GDISSYRILT
560 570 580 590 600
DILGLEDHLG DMDFKIAGTR RGITAIQLDI KPAGIPLDII CESLEPARKA
610 620 630 640 650
RNQILDRMDQ EISSARAFND GSSPRLATLS FSSDSLRKLL FHRKKIEQET
660 670 680 690 700
GARVSVSDGT VTIVAKTQPI MDKAIEKVEF LVGREIEVGR TYKGVVSSIK
710 720 730 740 750
EYGAFVEFNG GQQGLLHISE LSHDKVSKVS DVVSVGQVLS LTCIGQDLRG
760 770 780 790 800
NIKLSLKATL PHAHEKKDLA SNHTDPLPSQ EVVGWTAVEN MPSKDANAEP
810 820 830 840 850
SISKDEDNMI EETPGCSTPA VIIRSAAECD AQDVTNDPKK KRPKVAKSSP
860 870 880 890 900
KLSKPASERQ EVKRTSAKKT SGASTTAKKN KKEKADSSND VLDAIPEQNK
910 920 930 940 950
SNIMNYSSPS NFRSGSMKLG DVVTAKVYQI RAYGLVLELS DGVRGMHKFA
960 970 980
ENGHKDFEVG EELLVKCSSF NAKGIPVFSL LD
Length:982
Mass (Da):107,028
Last modified:July 5, 2004 - v1
Checksum:i0B05E5A0E8684351
GO

Sequence cautioni

The sequence BAF09358 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003980 Genomic DNA Translation: BAD21450.1
AP008208 Genomic DNA Translation: BAF09358.1 Sequence problems.
AP014958 Genomic DNA No translation available.
AK058997 mRNA No translation available.
UniGeneiOs.37362

Genome annotation databases

EnsemblPlantsiOs02t0617700-01; Os02t0617700-01; Os02g0617700
GrameneiOs02t0617700-01; Os02t0617700-01; Os02g0617700

Similar proteinsi

Entry informationi

Entry nameiPNP2_ORYSJ
AccessioniPrimary (citable) accession number: Q6KAI0
Secondary accession number(s): Q0DZI0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2012
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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