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Q6K8E7 (LCB1B_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Long chain base biosynthesis protein 1b

EC=2.3.1.50
Gene names
Ordered Locus Names:Os02g0806900, LOC_Os02g56300
ORF Names:OJ1111_C07.25, OsJ_08792
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length481 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Serine palmitoyltransferase (SPT). The heterodimer formed with LCB2 constitutes the catalytic core By similarity.

Catalytic activity

Palmitoyl-CoA + L-serine = CoA + 3-dehydro-D-sphinganine + CO2.

Cofactor

Pyridoxal phosphate By similarity.

Pathway

Lipid metabolism; sphingolipid metabolism.

Subunit structure

Heterodimer with LCB2. Component of the serine palmitoyltransferase (SPT) complex, composed of LCB1 and LCB2 By similarity.

Subcellular location

Endoplasmic reticulum membrane; Single-pass membrane protein By similarity.

Sequence similarities

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 481481Long chain base biosynthesis protein 1b
PRO_0000419148

Regions

Transmembrane32 – 5221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q6K8E7 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 42942D30AAF65F18

FASTA48152,010
        10         20         30         40         50         60 
MEMVLPVANA TAAALARVSA MFNAPLARAV VFGIHIDGHL VVEGLLIAAI LFQLSRKSYK 

        70         80         90        100        110        120 
PPKKPLTERE VDELCDEWQP EPLCPPIKEG ARIEAPTLES AAGPHTIVDG KEVVNFASAN 

       130        140        150        160        170        180 
YLGLIGNEKI LDSCIGSVEK YGVGSCGPRG FYGTIDVHLD CETKIAKFLG TQDSILYSYG 

       190        200        210        220        230        240 
ISTIFSVIPA FCKKGDIIVA DEGVHWAVQN GLQLSRSTVV YFKHNDMASL ASTLEKLTHG 

       250        260        270        280        290        300 
NKRTEKIRRY IVVEAIYQNS GQIAPLDEIV RLKEKYRFRV ILEESHSFGV LGKSGRGLAE 

       310        320        330        340        350        360 
HYGVPIEKID IITAGMGNAL ATDGGFCTGS IRVVDHQRLS SSGYVFSASL PPYLASAAIS 

       370        380        390        400        410        420 
AVDHLEENPS VLANLRSNIT LLHKELSDVQ GLEIASNILS PIVFLKLKTS TGSAVADLEL 

       430        440        450        460        470        480 
LEVISEKVLK EDSVFIAATK RSSLDKCRLP VGIRLFVSAG HTESDILKVS ESLKRVAASV 


L 

« Hide

References

« Hide 'large scale' references
[1]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[3]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[4]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP004153 Genomic DNA. Translation: BAD19391.1.
AP008208 Genomic DNA. Translation: BAF10365.2.
CM000139 Genomic DNA. Translation: EEE58013.1.
AK073935 mRNA. Translation: BAG93720.1.
AK105851 mRNA. Translation: BAG97394.1.
RefSeqNP_001048451.2. NM_001054986.1.
UniGeneOs.6404.

3D structure databases

ProteinModelPortalQ6K8E7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING39946.BGIOSIBCE009051.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS02T0806900-01; OS02T0806900-01; OS02G0806900.
GeneID4331075.
KEGGosa:4331075.

Organism-specific databases

GrameneQ6K8E7.

Phylogenomic databases

eggNOGCOG0156.
KOK00654.
OMACALEAME.

Enzyme and pathway databases

UniPathwayUPA00222.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
InterProIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMSSF53383. SSF53383. 1 hit.
ProtoNetSearch...

Entry information

Entry nameLCB1B_ORYSJ
AccessionPrimary (citable) accession number: Q6K8E7
Secondary accession number(s): Q0DWM3
Entry history
Integrated into UniProtKB/Swiss-Prot: October 3, 2012
Last sequence update: July 5, 2004
Last modified: May 14, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

PATHWAY comments

Index of metabolic and biosynthesis pathways