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Q6K8E7

- LCB1B_ORYSJ

UniProt

Q6K8E7 - LCB1B_ORYSJ

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Protein

Long chain base biosynthesis protein 1b

Gene

Os02g0806900

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Serine palmitoyltransferase (SPT). The heterodimer formed with LCB2 constitutes the catalytic core (By similarity).By similarity

Catalytic activityi

Palmitoyl-CoA + L-serine = CoA + 3-dehydro-D-sphinganine + CO2.

Cofactori

Pathwayi

GO - Molecular functioni

  1. pyridoxal phosphate binding Source: InterPro
  2. serine C-palmitoyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. biosynthetic process Source: InterPro
  2. sphingolipid metabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Lipid metabolism, Sphingolipid metabolism

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

ReactomeiREACT_220105. Sphingolipid de novo biosynthesis.
UniPathwayiUPA00222.

Names & Taxonomyi

Protein namesi
Recommended name:
Long chain base biosynthesis protein 1b (EC:2.3.1.50)
Gene namesi
Ordered Locus Names:Os02g0806900, LOC_Os02g56300
ORF Names:OJ1111_C07.25, OsJ_08792
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 2

Organism-specific databases

GrameneiQ6K8E7.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei32 – 5221HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. endoplasmic reticulum Source: UniProtKB-KW
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 481481Long chain base biosynthesis protein 1bPRO_0000419148Add
BLAST

Interactioni

Subunit structurei

Heterodimer with LCB2. Component of the serine palmitoyltransferase (SPT) complex, composed of LCB1 and LCB2 (By similarity).By similarity

Protein-protein interaction databases

STRINGi39946.BGIOSIBCE009051.

Structurei

3D structure databases

ProteinModelPortaliQ6K8E7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0156.
InParanoidiQ6K8E7.
KOiK00654.
OMAiCALEAME.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6K8E7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEMVLPVANA TAAALARVSA MFNAPLARAV VFGIHIDGHL VVEGLLIAAI
60 70 80 90 100
LFQLSRKSYK PPKKPLTERE VDELCDEWQP EPLCPPIKEG ARIEAPTLES
110 120 130 140 150
AAGPHTIVDG KEVVNFASAN YLGLIGNEKI LDSCIGSVEK YGVGSCGPRG
160 170 180 190 200
FYGTIDVHLD CETKIAKFLG TQDSILYSYG ISTIFSVIPA FCKKGDIIVA
210 220 230 240 250
DEGVHWAVQN GLQLSRSTVV YFKHNDMASL ASTLEKLTHG NKRTEKIRRY
260 270 280 290 300
IVVEAIYQNS GQIAPLDEIV RLKEKYRFRV ILEESHSFGV LGKSGRGLAE
310 320 330 340 350
HYGVPIEKID IITAGMGNAL ATDGGFCTGS IRVVDHQRLS SSGYVFSASL
360 370 380 390 400
PPYLASAAIS AVDHLEENPS VLANLRSNIT LLHKELSDVQ GLEIASNILS
410 420 430 440 450
PIVFLKLKTS TGSAVADLEL LEVISEKVLK EDSVFIAATK RSSLDKCRLP
460 470 480
VGIRLFVSAG HTESDILKVS ESLKRVAASV L
Length:481
Mass (Da):52,010
Last modified:July 5, 2004 - v1
Checksum:i42942D30AAF65F18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004153 Genomic DNA. Translation: BAD19391.1.
AP008208 Genomic DNA. Translation: BAF10365.2.
CM000139 Genomic DNA. Translation: EEE58013.1.
AK073935 mRNA. Translation: BAG93720.1.
AK105851 mRNA. Translation: BAG97394.1.
RefSeqiNP_001048451.2. NM_001054986.1.
UniGeneiOs.6404.

Genome annotation databases

EnsemblPlantsiOS02T0806900-01; OS02T0806900-01; OS02G0806900.
GeneIDi4331075.
KEGGiosa:4331075.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004153 Genomic DNA. Translation: BAD19391.1 .
AP008208 Genomic DNA. Translation: BAF10365.2 .
CM000139 Genomic DNA. Translation: EEE58013.1 .
AK073935 mRNA. Translation: BAG93720.1 .
AK105851 mRNA. Translation: BAG97394.1 .
RefSeqi NP_001048451.2. NM_001054986.1.
UniGenei Os.6404.

3D structure databases

ProteinModelPortali Q6K8E7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 39946.BGIOSIBCE009051.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS02T0806900-01 ; OS02T0806900-01 ; OS02G0806900 .
GeneIDi 4331075.
KEGGi osa:4331075.

Organism-specific databases

Gramenei Q6K8E7.

Phylogenomic databases

eggNOGi COG0156.
InParanoidi Q6K8E7.
KOi K00654.
OMAi CALEAME.

Enzyme and pathway databases

UniPathwayi UPA00222 .
Reactomei REACT_220105. Sphingolipid de novo biosynthesis.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
InterProi IPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
Pfami PF00155. Aminotran_1_2. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  3. "The genomes of Oryza sativa: a history of duplications."
    Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
    , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
    PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  4. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiLCB1B_ORYSJ
AccessioniPrimary (citable) accession number: Q6K8E7
Secondary accession number(s): Q0DWM3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2012
Last sequence update: July 5, 2004
Last modified: November 26, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3