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Protein

Long chain base biosynthesis protein 1b

Gene

Os02g0806900

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Serine palmitoyltransferase (SPT). The heterodimer formed with LCB2 constitutes the catalytic core (By similarity).By similarity

Catalytic activityi

Palmitoyl-CoA + L-serine = CoA + 3-dehydro-D-sphinganine + CO2.

Cofactori

Pathwayi: sphingolipid metabolism

This protein is involved in the pathway sphingolipid metabolism, which is part of Lipid metabolism.
View all proteins of this organism that are known to be involved in the pathway sphingolipid metabolism and in Lipid metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase
Biological processLipid metabolism, Sphingolipid metabolism
LigandPyridoxal phosphate

Enzyme and pathway databases

UniPathwayiUPA00222

Names & Taxonomyi

Protein namesi
Recommended name:
Long chain base biosynthesis protein 1b (EC:2.3.1.50)
Gene namesi
Ordered Locus Names:Os02g0806900, LOC_Os02g56300
ORF Names:OJ1111_C07.25, OsJ_08792
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei32 – 52HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004191481 – 481Long chain base biosynthesis protein 1bAdd BLAST481

Proteomic databases

PaxDbiQ6K8E7

Expressioni

Gene expression databases

ExpressionAtlasiQ6K8E7 baseline and differential
GenevisibleiQ6K8E7 OS

Interactioni

Subunit structurei

Heterodimer with LCB2. Component of the serine palmitoyltransferase (SPT) complex, composed of LCB1 and LCB2 (By similarity).By similarity

Protein-protein interaction databases

STRINGi39947.LOC_Os02g56300.1

Structurei

3D structure databases

ProteinModelPortaliQ6K8E7
SMRiQ6K8E7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1358 Eukaryota
COG0156 LUCA
InParanoidiQ6K8E7
KOiK00654
OMAiVQALYEX
OrthoDBiEOG0936091M

Family and domain databases

Gene3Di3.40.640.101 hit
3.90.1150.102 hits
InterProiView protein in InterPro
IPR004839 Aminotransferase_I/II
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PfamiView protein in Pfam
PF00155 Aminotran_1_2, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit

Sequencei

Sequence statusi: Complete.

Q6K8E7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEMVLPVANA TAAALARVSA MFNAPLARAV VFGIHIDGHL VVEGLLIAAI
60 70 80 90 100
LFQLSRKSYK PPKKPLTERE VDELCDEWQP EPLCPPIKEG ARIEAPTLES
110 120 130 140 150
AAGPHTIVDG KEVVNFASAN YLGLIGNEKI LDSCIGSVEK YGVGSCGPRG
160 170 180 190 200
FYGTIDVHLD CETKIAKFLG TQDSILYSYG ISTIFSVIPA FCKKGDIIVA
210 220 230 240 250
DEGVHWAVQN GLQLSRSTVV YFKHNDMASL ASTLEKLTHG NKRTEKIRRY
260 270 280 290 300
IVVEAIYQNS GQIAPLDEIV RLKEKYRFRV ILEESHSFGV LGKSGRGLAE
310 320 330 340 350
HYGVPIEKID IITAGMGNAL ATDGGFCTGS IRVVDHQRLS SSGYVFSASL
360 370 380 390 400
PPYLASAAIS AVDHLEENPS VLANLRSNIT LLHKELSDVQ GLEIASNILS
410 420 430 440 450
PIVFLKLKTS TGSAVADLEL LEVISEKVLK EDSVFIAATK RSSLDKCRLP
460 470 480
VGIRLFVSAG HTESDILKVS ESLKRVAASV L
Length:481
Mass (Da):52,010
Last modified:July 5, 2004 - v1
Checksum:i42942D30AAF65F18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004153 Genomic DNA Translation: BAD19391.1
AP008208 Genomic DNA Translation: BAF10365.2
AP014958 Genomic DNA Translation: BAS81479.1
CM000139 Genomic DNA Translation: EEE58013.1
AK073935 mRNA Translation: BAG93720.1
AK105851 mRNA Translation: BAG97394.1
RefSeqiXP_015622652.1, XM_015767166.1
UniGeneiOs.6404

Genome annotation databases

EnsemblPlantsiOs02t0806900-01; Os02t0806900-01; Os02g0806900
GeneIDi4331075
GrameneiOs02t0806900-01; Os02t0806900-01; Os02g0806900
KEGGiosa:4331075

Similar proteinsi

Entry informationi

Entry nameiLCB1B_ORYSJ
AccessioniPrimary (citable) accession number: Q6K8E7
Secondary accession number(s): A0A0P0VQY7, Q0DWM3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2012
Last sequence update: July 5, 2004
Last modified: February 28, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome