Q6K6N7 (P2C14_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable protein phosphatase 2C 14
Short name=OsPP2C14
EC=3.1.3.16

Gene names

Ordered Locus Names:	Os02g0471500, LOC_Os02g27220
ORF Names:	P0046H03.1, P0403C01.30

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	518 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.

Ontologies

Keywords
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	metabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	nucleus Inferred from electronic annotation. Source: EnsemblPlants/Gramene
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoprotein phosphatase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 518	518	Probable protein phosphatase 2C 14		PRO_0000363260
Regions
	Domain	128 – 422	295	PP2C-like
	Compositional bias	26 – 31	6	Poly-Gln
	Compositional bias	56 – 60	5	Poly-Gly
Sites
	Metal binding	165	1	Manganese 1 By similarity
	Metal binding	165	1	Manganese 2 By similarity
	Metal binding	166	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	382	1	Manganese 2 By similarity
	Metal binding	428	1	Manganese 2 By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6K6N7 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: D9557DD21A873599	FASTA	518	55,284
	10 20 30 40 50 60 MVEAAAGRRS GANRRRPSGG GERRRQQQQH QRLVAVAVAA RVVMVAPAAT PAPAAGGGGG 70 80 90 100 110 120 CVEDILGCLL GVLRALGVTW AAAARPQRQQ PRLAAQTPRG PAPGADGRRA AAELRGIPGR 130 140 150 160 170 180 IAGNGACAVA SLYTLQGKKG VNQDAMIVWE NFCSREDTIF CGVFDGHGPN GHLVAKRVRD 190 200 210 220 230 240 LLPIKLGADL GTDEGRQTST SSIKSNGDET GSPGNMGRDA EQNGEYPEIF TALRTSFLRA 250 260 270 280 290 300 FNVMDRDLKL HKSIDCFFSG TTAVAVLKQG RNLIIGNLGD SRAILGTRDK DNQLMAVQLT 310 320 330 340 350 360 VDLKPNIPSE AQRIRQRRGR IFALPEEPEV ARVWLPKYNS PGLAMARAFG DFCLKDYGLI 370 380 390 400 410 420 SMPEVSYHRI TEKDEFVVLA TDGVWDVLSN TEVVSIVNRA TSRASAARLL VESAHRAWRA 430 440 450 460 470 480 RFPTSKIDDC AVVCLFLDTD ELSETSSSMA RDMTNAVEVS SGQHSNTIQL STGVSSDVVT 490 500 510 AVLTDGDDLS AVDAVAKLVT LTDLPNNASG ATQSITTK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[3]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[4]	"Leaf-associated cDNA encoding a putaitve protein phosphatase 2C." Lee R.H., Chen S.C.G. Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 389-518. Strain: cv. Tainung 57. Tissue: Seedling leaf.
[5]	"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis." Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y. BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP004787 Genomic DNA. Translation: BAD19485.1. AP005065 Genomic DNA. Translation: BAD19608.1. AP008208 Genomic DNA. Translation: BAF08749.1. AK120615 mRNA. Translation: BAH00094.1. AF358769 mRNA. Translation: AAL83985.1.
RefSeq	NP_001046835.1. NM_001053370.1.
UniGene	Os.9705.
3D structure databases
HSSP	HSSP built from PDB template 1A6Q based on UniProtKB P35813.
ProteinModelPortal	Q6K6N7.
ModBase	Search...
Proteomic databases
PRIDE	Q6K6N7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os02g27220.1; LOC_Os02g27220.1; LOC_Os02g27220.
GeneID	4329347.
KEGG	osa:4329347.
Organism-specific databases
Gramene	Q6K6N7.
Phylogenomic databases
eggNOG	COG0631.
HOGENOM	HOG000233897.
OMA	QNGEYPE.
ProtClustDB	CLSN2692729.
Gene expression databases
ArrayExpress	Q6K6N7.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. IPR015655. Protein_Pase_2C. [Graphical view]
PANTHER	PTHR13832. PTHR13832. 1 hit.
Pfam	PF00481. PP2C. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
PROSITE	PS01032. PP2C. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P2C14_ORYSJ

Accession

Primary (citable) accession number: Q6K6N7
Secondary accession number(s): Q8RVS2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	July 5, 2004
Last modified:	April 3, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program