Q6K471 (FTRC_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic
Short name=FTR-C
EC=1.8.7.2

Gene names

Ordered Locus Names:	Os09g0249900, LOC_Os09g07570
ORF Names:	OJ1116_H10.13, OJ1695_A02.34, OsJ_28527

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	146 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	FTR is a [4Fe-4S] protein playing a central role in the ferredoxin/thioredoxin regulatory chain. It converts an electron signal (photoreduced ferredoxin) to a thiol signal (reduced thioredoxin) in the regulation of enzymes by reduction of specific disulfide groups. Catalyzes the light-dependent activation of several photosynthetic enzymes By similarity.
Catalytic activity	2 reduced ferredoxin + thioredoxin disulfide = 2 oxidized ferredoxin + thioredoxin + 2 H+.
Subunit structure	Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit) By similarity.
Subcellular location	Plastid › chloroplast Potential.
Sequence caution	The sequence BAF24589.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
Cellular component	Chloroplast Plastid
Domain	Redox-active center Transit peptide
Ligand	4Fe-4S Iron Iron-sulfur Metal-binding
Molecular function	Oxidoreductase
PTM	Disulfide bond
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	chloroplast Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	4 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW ferredoxin-NAD(P) reductase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 26	26	Chloroplast Potential
	Chain	27 – 146	120	Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic		PRO_0000394860
Sites
	Metal binding	85	1	Iron-sulfur (4Fe-4S) By similarity
	Metal binding	104	1	Iron-sulfur (4Fe-4S) By similarity
	Metal binding	106	1	Iron-sulfur (4Fe-4S) By similarity
	Metal binding	115	1	Iron-sulfur (4Fe-4S) By similarity
Amino acid modifications
	Disulfide bond	87 ↔ 117		Redox-active By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6K471 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: F4D88399C9857D90	FASTA	146	16,101
	10 20 30 40 50 60 MMSMASTTAS PFCPSPMPRG RKCTVRVQAG AAGADASDKS LEIMRKFSEQ YARRSNTFFC 70 80 90 100 110 120 SEKSVTAVVI KGLADHKDQL GAPLCPCRHY DDKAAEVAQG FWNCPCVPMR ERKECHCMLF 130 140 LTPDNDFAGQ DQAITLEEIK DATSKI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[3]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[4]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP005578 Genomic DNA. Translation: BAD19914.1. AP005553 Genomic DNA. Translation: BAD22216.1. AP008215 Genomic DNA. Translation: BAF24589.2. Different initiation. CM000146 Genomic DNA. Translation: EEE69266.1. AK099860 mRNA. Translation: BAG94324.1.
RefSeq	NP_001062675.2. NM_001069210.1.
UniGene	Os.5370.
3D structure databases
ProteinModelPortal	Q6K471.
ModBase	Search...
Proteomic databases
PaxDb	Q6K471.
PRIDE	Q6K471.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os09g07570.1; LOC_Os09g07570.1; LOC_Os09g07570.
GeneID	4346508.
KEGG	osa:4346508.
Organism-specific databases
Gramene	Q6K471.
Phylogenomic databases
eggNOG	COG4802.
OMA	QYAKRTG.
ProtClustDB	CLSN2683009.
Gene expression databases
ArrayExpress	Q6K471.
Family and domain databases
Gene3D	3.90.460.10. 1 hit.
InterPro	IPR024707. FTR_bsu. IPR004209. FTR_bsu_dom. [Graphical view]
Pfam	PF02943. FeThRed_B. 1 hit. [Graphical view]
PIRSF	PIRSF000260. FTRc. 1 hit.
SUPFAM	SSF57662. Fe/thioredoxin_red_bsu-like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FTRC_ORYSJ

Accession

Primary (citable) accession number: Q6K471
Secondary accession number(s): Q0J376

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 15, 2010
Last sequence update:	July 5, 2004
Last modified:	April 3, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program