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Protein
Submitted name:

Aquaporin 1 splice variant 3

Gene

AQP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. glycerol transmembrane transporter activity Source: Ensembl
  2. potassium ion transmembrane transporter activity Source: Ensembl
  3. water channel activity Source: Ensembl

GO - Biological processi

  1. camera-type eye morphogenesis Source: Ensembl
  2. corticotropin secretion Source: Ensembl
  3. glomerular filtration Source: Ensembl
  4. hyperosmotic salinity response Source: Ensembl
  5. lateral ventricle development Source: Ensembl
  6. lipid digestion Source: Ensembl
  7. maintenance of symbiont-containing vacuole by host Source: Ensembl
  8. metanephric descending thin limb development Source: Ensembl
  9. metanephric glomerulus vasculature development Source: Ensembl
  10. metanephric proximal convoluted tubule segment 2 development Source: Ensembl
  11. metanephric proximal straight tubule development Source: Ensembl
  12. positive regulation of epithelial cell migration Source: Ensembl
  13. positive regulation of lamellipodium assembly Source: Ensembl
  14. renal water absorption Source: Ensembl
  15. response to estrogen Source: Ensembl
  16. secretory granule organization Source: Ensembl
  17. sensory perception of pain Source: Ensembl
  18. wound healing Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Aquaporin 1 splice variant 3Imported
Gene namesi
Name:AQP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. apical plasma membrane Source: Ensembl
  2. axon terminus Source: Ensembl
  3. basolateral plasma membrane Source: Ensembl
  4. brush border Source: Ensembl
  5. extracellular vesicular exosome Source: Ensembl
  6. integral component of membrane Source: Ensembl
  7. neuronal cell body membrane Source: Ensembl
  8. symbiont-containing vacuole Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ6JSD7.

Expressioni

Gene expression databases

BgeeiQ6JSD7.
ExpressionAtlasiQ6JSD7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ6JSD7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000288286.

Family and domain databases

Gene3Di1.20.1080.10. 1 hit.
InterProiIPR023271. Aquaporin-like.
IPR023274. Aquaporin_1.
IPR000425. MIP.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 1 hit.
[Graphical view]
PRINTSiPR02013. AQUAPORIN1.
SUPFAMiSSF81338. SSF81338. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q6JSD7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
CGINPARSFG SAVITHNFSN HWIFWVGPFI GGALAVLIYD FILAPRSSDL
60 70 80
TDRVKVWTSG QVEEYDLDAD DINSRVEMKP K
Length:81
Mass (Da):9,056
Last modified:July 4, 2004 - v1
Checksum:i3962857DA7D4F02F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY312581 mRNA. Translation: AAR16186.1.
UniGeneiHs.76152.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY312581 mRNA. Translation: AAR16186.1.
UniGeneiHs.76152.

3D structure databases

ProteinModelPortaliQ6JSD7.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ6JSD7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000288286.

Miscellaneous databases

ChiTaRSiAQP1. human.

Gene expression databases

BgeeiQ6JSD7.
ExpressionAtlasiQ6JSD7. baseline and differential.

Family and domain databases

Gene3Di1.20.1080.10. 1 hit.
InterProiIPR023271. Aquaporin-like.
IPR023274. Aquaporin_1.
IPR000425. MIP.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 1 hit.
[Graphical view]
PRINTSiPR02013. AQUAPORIN1.
SUPFAMiSSF81338. SSF81338. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Transcriptional profiling of asthma candidate genes in 11 asthma related cell lines and lung tissue."
    Polvi A., Ruosaari S., Vendelin J., West A., Saarikko I., Reinikainen A., Hollmen J., Laitinen T., Mannila H., Lahesmaa R., Kere J.
    Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LungImported.

Entry informationi

Entry nameiQ6JSD7_HUMAN
AccessioniPrimary (citable) accession number: Q6JSD7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 4, 2004
Last sequence update: July 4, 2004
Last modified: November 25, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.