SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6JIZ0

- Q6JIZ0_MOUSE

UniProt

Q6JIZ0 - Q6JIZ0_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: Acetyl-CoA carboxylase 2
Gene
Acacb
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Cofactori

Biotin By similarity.SAAS annotations

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. acetyl-CoA carboxylase activity Source: MGI
  3. biotin carboxylase activity Source: InterPro
  4. metal ion binding Source: InterPro

GO - Biological processi

  1. fatty acid biosynthetic process Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotations

Keywords - Ligandi

ATP-bindingSAAS annotations, BiotinSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BRENDAi6.4.1.2. 244.

Names & Taxonomyi

Protein namesi
Submitted name:
Acetyl-CoA carboxylase 2Imported
Gene namesi
Name:AcacbImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2140940. Acacb.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ6JIZ0.

PTM databases

PhosphoSiteiQ6JIZ0.

Expressioni

Gene expression databases

GenevestigatoriQ6JIZ0.

Interactioni

Protein-protein interaction databases

MINTiMINT-1859452.

Structurei

3D structure databases

ProteinModelPortaliQ6JIZ0.
SMRiQ6JIZ0. Positions 229-749, 875-967, 1683-2409.

Family & Domainsi

Sequence similaritiesi

Contains ATP-grasp domain.SAAS annotations
Contains biotin carboxylation domain.SAAS annotations
Contains biotinyl-binding domain.SAAS annotations

Phylogenomic databases

HOGENOMiHOG000214115.
HOVERGENiHBG005371.
InParanoidiQ6JIZ0.
KOiK11262.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
3.90.226.10. 3 hits.
InterProiIPR013537. AcCoA_COase_cen.
IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR011764. Biotin_carboxylation_dom.
IPR005482. Biotin_COase_C.
IPR000089. Biotin_lipoyl.
IPR005481. CarbamoylP_synth_lsu_N.
IPR000022. Carboxyl_trans.
IPR005479. CbamoylP_synth_lsu-like_ATP-bd.
IPR029045. ClpP/crotonase-like_dom.
IPR011763. COA_CT_C.
IPR011762. COA_CT_N.
IPR016185. PreATP-grasp_dom.
IPR011054. Rudment_hybrid_motif.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamiPF08326. ACC_central. 1 hit.
PF02785. Biotin_carb_C. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF01039. Carboxyl_trans. 1 hit.
PF00289. CPSase_L_chain. 1 hit.
PF02786. CPSase_L_D2. 1 hit.
[Graphical view]
SMARTiSM00878. Biotin_carb_C. 1 hit.
[Graphical view]
SUPFAMiSSF51230. SSF51230. 1 hit.
SSF51246. SSF51246. 1 hit.
SSF52096. SSF52096. 2 hits.
SSF52440. SSF52440. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
PS50979. BC. 1 hit.
PS50968. BIOTINYL_LIPOYL. 1 hit.
PS50989. COA_CT_CTER. 1 hit.
PS50980. COA_CT_NTER. 1 hit.
PS00866. CPSASE_1. 1 hit.
PS00867. CPSASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6JIZ0-1 [UniParc]FASTAAdd to Basket

« Hide

MVLLLFLTCL VFSCLTFSWL KIWGKMTDSK PLTNSKVEAN LLSSEESLSA     50
SELSGEQLQE HGDHSCLSYR GPRDASQQRN SLPSSCQRPP RNPLSSNDTW 100
PSPELQTNWT AAPGPEVPDA NGLPFPARPP SQRTVSPSRE DRKQAHIKRQ 150
LMTSFILGSL DDNSSDEDPS AGSFQNSSRK SSRASLGTLS QEAALNTSDP 200
ESHAPTMRPS MSGLHLVKRG REHKKLDLHR DFTVASPAEF VTRFGGNRVI 250
EKVLIANNGI AAVKCMRSIR RWAYEMFRNE RAIRFVVMVT PEDLKANAEY 300
IKMADQYVPV PGGPNNNNYA NVELIIDIAK RIPVQAVWAG WGHASENPKL 350
PELLCKHEIA FLGPPSEAMW ALGDKIASTI VAQTLQIPTL PWSGSGLTVE 400
WTEDSRHQGK CISVPEDVYE QGCVKDVDEG LQAAEKIGFP LMIKASEGGG 450
GKGIRKAESA EDFPMLFRQV QSEIPGSPIF LMKLAQNARH LEVQVLADQY 500
GNAVSLFGRD CSIQRRHQKI IEEAPATIAA PAVSEFMEQC AVLLAKMVGY 550
VSAGTVEYLY SRDGSFHFLE LNPRLQVEHP CTEMIADVNL PAAQLQIAMG 600
VPLHRLKDIR LLYGESPWGV TPIPFETPLS PPIARGHVIA ARITSENPDE 650
GFKPSSGTVQ ELNFRSNKNV WGYFSVAAAG GLHEFADSQF GHCFSWGENR 700
EEAISNMVVA LKELSIRGDF RTTVEYLVNL LETESFQNND IDTGWLDHLI 750
AQRVQAEKPD IMLGVVCGAL NVADAMFRTC MTEFLHSLER GQVLPADSLL 800
NIVDVELIYG GIKYALKVAR QSLTMFVLIM NGCHIEIDAH RLNDGGLLLS 850
YNGSSYTTYM KEEVDSYRIT IGNKTCVFEK ENDPTVLRSP SAGKLMQYTV 900
EDGDHVEAGS SYAEMEVMKM IMTLNVQESG RVKYIKRPGV ILEAGCVVAR 950
LELDDPSKVH AAQPFTGELP AQQTLPILGE KLHQVFHGVL ENLTNVMSGY 1000
CLPEPFFSMK LKDWVQKLMM TLRHPSLPLL ELQEIMTSVA GRIPAPVEKA 1050
VRRVMAQYAS NITSVLCQFP SQQIATILDC HAATLQRKAD REVFFMNTQS 1100
IVQLVQRYRS GTRGYMKAVV LDLLRKYLNV EHHFQQAHYD KCVINLREQF 1150
KPDMTQVLDC IFSHSQVAKK NQLVTMLIDE LCGPDPTLSD ELTSILCELT 1200
QLSRSEHCKV ALRARQVLIA SHLPSYELRH NQVESIFLSA IDMYGHQFCP 1250
ENLKKLILSE TTIFDVLPTF FYHENKVVCM ASLEVYVRRG YIAYELNSLQ 1300
HRELPDGTCV VEFQSMLPSS HPNRMAVPIS VSNPDLLRHS TELFMDSGFS 1350
PLCQRMGAMV AFRRFEEFTR NFDEVISCFA NVQTDTLLFS KACTSLYSEE 1400
DNKSLREEPI HILNVAIQCA DHMEDEALVP VFRAFVQSKK HILVDYGLRR 1450
ITFLVAQERE FPKFFTFRAR DEFAEDRIYR HLEPALAFQL ELSRMRNFDL 1500
TAVPCANHKM HLYLGAAKVK EGLEVTDHRF FIRAIIRHSD LITKEASFEY 1550
LQNEGERLLL EAMDELEVAF NNTSVRTDCN HIFLNFVPTV IMDPLKIEES 1600
VRDMVMRYGS RLWKLRVLQA EVKINIRQTT SDSAIPIRLF ITNESGYYLD 1650
ISLYREVTDS RSGNIMFHSF GNKQGSLHGM LINTPYVTKD LLQAKRFQAQ 1700
SLGTTYVYDF PEMFRQALFK LWGSPEKYPK DILTYTELVL DSQGQLVEMN 1750
RLPGCNEVGM VAFKMRFKTP EYPEGRDAVV IGNDITFQIG SFGIGEDFLY 1800
LRASEMARTE GIPQIYLAAN SGARMGLAEE IKQIFQVAWV DPEDPHKGFR 1850
YLYLTPQDYT QISSQNSVHC KHIEDEGESR YVIVDVIGKD ANLGVENLRG 1900
SGMIAGEASL AYEKTVTISM VTCRALGIGA YLVRLGQRVI QVENSHIILT 1950
GAGALNKVLG REVYTSNNQL GGVQIMHTNG VSHVTVPDDF EGVCTILEWL 2000
SFIPKDNRSP VPITTPSDPI DREIEFTPTK APYDPRWMLA GRPHPTLKGT 2050
WQSGFFDHGS FKEIMAPWAQ TVVTGRARLG GIPVGVIAVE TRTVEVAVPA 2100
DPANLDSEAK IIQQAGQVWF PDSAYKTAQV IRDFNKERLP LMIFANWRGF 2150
SGGMKDMYEQ MLKFGAYIVD GLRLYEQPIL IYIPPCAELR GGSWVVLDST 2200
INPLCIEMYA DKESRGGVLE PEGTVEIKFR KKDLVKTIRR IDPVCKKLVG 2250
QLGKAQLPDK DRKELEGQLK AREELLLPIY HQVAVQFADL HDTPGHMLEK 2300
GIISDVLEWK TARTFFYWRL RRLLLEAQVK QEILRASPEL SHEHTQSMLR 2350
RWFVETEGAV KAYLWDSNQV VVQWLEQHWS AKDGLRSTIR ENINYLKRDS 2400
VLKTIQSLVQ EHPEVIMDCV AYLSQHLTPA ERIQVAQLLS TTESPASS 2448
Length:2,448
Mass (Da):275,668
Last modified:July 5, 2004 - v1
Checksum:i0B8649F5D2CF1C8A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY451394 mRNA. Translation: AAS13686.1.
RefSeqiNP_598665.2. NM_133904.2.
UniGeneiMm.81793.

Genome annotation databases

GeneIDi100705.
KEGGimmu:100705.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY451394 mRNA. Translation: AAS13686.1 .
RefSeqi NP_598665.2. NM_133904.2.
UniGenei Mm.81793.

3D structure databases

ProteinModelPortali Q6JIZ0.
SMRi Q6JIZ0. Positions 229-749, 875-967, 1683-2409.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-1859452.

PTM databases

PhosphoSitei Q6JIZ0.

Proteomic databases

PRIDEi Q6JIZ0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 100705.
KEGGi mmu:100705.

Organism-specific databases

CTDi 32.
MGIi MGI:2140940. Acacb.

Phylogenomic databases

HOGENOMi HOG000214115.
HOVERGENi HBG005371.
InParanoidi Q6JIZ0.
KOi K11262.

Enzyme and pathway databases

BRENDAi 6.4.1.2. 244.

Miscellaneous databases

ChiTaRSi ACACB. mouse.
NextBioi 354598.
SOURCEi Search...

Gene expression databases

Genevestigatori Q6JIZ0.

Family and domain databases

Gene3Di 3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
3.90.226.10. 3 hits.
InterProi IPR013537. AcCoA_COase_cen.
IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR011764. Biotin_carboxylation_dom.
IPR005482. Biotin_COase_C.
IPR000089. Biotin_lipoyl.
IPR005481. CarbamoylP_synth_lsu_N.
IPR000022. Carboxyl_trans.
IPR005479. CbamoylP_synth_lsu-like_ATP-bd.
IPR029045. ClpP/crotonase-like_dom.
IPR011763. COA_CT_C.
IPR011762. COA_CT_N.
IPR016185. PreATP-grasp_dom.
IPR011054. Rudment_hybrid_motif.
IPR011053. Single_hybrid_motif.
[Graphical view ]
Pfami PF08326. ACC_central. 1 hit.
PF02785. Biotin_carb_C. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF01039. Carboxyl_trans. 1 hit.
PF00289. CPSase_L_chain. 1 hit.
PF02786. CPSase_L_D2. 1 hit.
[Graphical view ]
SMARTi SM00878. Biotin_carb_C. 1 hit.
[Graphical view ]
SUPFAMi SSF51230. SSF51230. 1 hit.
SSF51246. SSF51246. 1 hit.
SSF52096. SSF52096. 2 hits.
SSF52440. SSF52440. 1 hit.
PROSITEi PS50975. ATP_GRASP. 1 hit.
PS50979. BC. 1 hit.
PS50968. BIOTINYL_LIPOYL. 1 hit.
PS50989. COA_CT_CTER. 1 hit.
PS50980. COA_CT_NTER. 1 hit.
PS00866. CPSASE_1. 1 hit.
PS00867. CPSASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Alternative splicing in the mouse acetyl-CoA carboxylase 2 (ACC2) gene."
    Mao J., Wakil S.J.
    Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeartImported.

Entry informationi

Entry nameiQ6JIZ0_MOUSE
AccessioniPrimary (citable) accession number: Q6JIZ0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi