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Q6JIZ0 (Q6JIZ0_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:Acacb MGI 2140940
OrganismMus musculus (Mouse) EMBL AAS13686.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length2448 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Cofactor

Biotin By similarity. SAAS SAAS011764

Sequence similarities

Contains ATP-grasp domain. SAAS SAAS011053

Contains biotin carboxylation domain. SAAS SAAS011764

Contains biotinyl-binding domain. SAAS SAAS011764

Sequences

Sequence LengthMass (Da)Tools
Q6JIZ0 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 0B8649F5D2CF1C8A

FASTA2,448275,668
        10         20         30         40         50         60 
MVLLLFLTCL VFSCLTFSWL KIWGKMTDSK PLTNSKVEAN LLSSEESLSA SELSGEQLQE 

        70         80         90        100        110        120 
HGDHSCLSYR GPRDASQQRN SLPSSCQRPP RNPLSSNDTW PSPELQTNWT AAPGPEVPDA 

       130        140        150        160        170        180 
NGLPFPARPP SQRTVSPSRE DRKQAHIKRQ LMTSFILGSL DDNSSDEDPS AGSFQNSSRK 

       190        200        210        220        230        240 
SSRASLGTLS QEAALNTSDP ESHAPTMRPS MSGLHLVKRG REHKKLDLHR DFTVASPAEF 

       250        260        270        280        290        300 
VTRFGGNRVI EKVLIANNGI AAVKCMRSIR RWAYEMFRNE RAIRFVVMVT PEDLKANAEY 

       310        320        330        340        350        360 
IKMADQYVPV PGGPNNNNYA NVELIIDIAK RIPVQAVWAG WGHASENPKL PELLCKHEIA 

       370        380        390        400        410        420 
FLGPPSEAMW ALGDKIASTI VAQTLQIPTL PWSGSGLTVE WTEDSRHQGK CISVPEDVYE 

       430        440        450        460        470        480 
QGCVKDVDEG LQAAEKIGFP LMIKASEGGG GKGIRKAESA EDFPMLFRQV QSEIPGSPIF 

       490        500        510        520        530        540 
LMKLAQNARH LEVQVLADQY GNAVSLFGRD CSIQRRHQKI IEEAPATIAA PAVSEFMEQC 

       550        560        570        580        590        600 
AVLLAKMVGY VSAGTVEYLY SRDGSFHFLE LNPRLQVEHP CTEMIADVNL PAAQLQIAMG 

       610        620        630        640        650        660 
VPLHRLKDIR LLYGESPWGV TPIPFETPLS PPIARGHVIA ARITSENPDE GFKPSSGTVQ 

       670        680        690        700        710        720 
ELNFRSNKNV WGYFSVAAAG GLHEFADSQF GHCFSWGENR EEAISNMVVA LKELSIRGDF 

       730        740        750        760        770        780 
RTTVEYLVNL LETESFQNND IDTGWLDHLI AQRVQAEKPD IMLGVVCGAL NVADAMFRTC 

       790        800        810        820        830        840 
MTEFLHSLER GQVLPADSLL NIVDVELIYG GIKYALKVAR QSLTMFVLIM NGCHIEIDAH 

       850        860        870        880        890        900 
RLNDGGLLLS YNGSSYTTYM KEEVDSYRIT IGNKTCVFEK ENDPTVLRSP SAGKLMQYTV 

       910        920        930        940        950        960 
EDGDHVEAGS SYAEMEVMKM IMTLNVQESG RVKYIKRPGV ILEAGCVVAR LELDDPSKVH 

       970        980        990       1000       1010       1020 
AAQPFTGELP AQQTLPILGE KLHQVFHGVL ENLTNVMSGY CLPEPFFSMK LKDWVQKLMM 

      1030       1040       1050       1060       1070       1080 
TLRHPSLPLL ELQEIMTSVA GRIPAPVEKA VRRVMAQYAS NITSVLCQFP SQQIATILDC 

      1090       1100       1110       1120       1130       1140 
HAATLQRKAD REVFFMNTQS IVQLVQRYRS GTRGYMKAVV LDLLRKYLNV EHHFQQAHYD 

      1150       1160       1170       1180       1190       1200 
KCVINLREQF KPDMTQVLDC IFSHSQVAKK NQLVTMLIDE LCGPDPTLSD ELTSILCELT 

      1210       1220       1230       1240       1250       1260 
QLSRSEHCKV ALRARQVLIA SHLPSYELRH NQVESIFLSA IDMYGHQFCP ENLKKLILSE 

      1270       1280       1290       1300       1310       1320 
TTIFDVLPTF FYHENKVVCM ASLEVYVRRG YIAYELNSLQ HRELPDGTCV VEFQSMLPSS 

      1330       1340       1350       1360       1370       1380 
HPNRMAVPIS VSNPDLLRHS TELFMDSGFS PLCQRMGAMV AFRRFEEFTR NFDEVISCFA 

      1390       1400       1410       1420       1430       1440 
NVQTDTLLFS KACTSLYSEE DNKSLREEPI HILNVAIQCA DHMEDEALVP VFRAFVQSKK 

      1450       1460       1470       1480       1490       1500 
HILVDYGLRR ITFLVAQERE FPKFFTFRAR DEFAEDRIYR HLEPALAFQL ELSRMRNFDL 

      1510       1520       1530       1540       1550       1560 
TAVPCANHKM HLYLGAAKVK EGLEVTDHRF FIRAIIRHSD LITKEASFEY LQNEGERLLL 

      1570       1580       1590       1600       1610       1620 
EAMDELEVAF NNTSVRTDCN HIFLNFVPTV IMDPLKIEES VRDMVMRYGS RLWKLRVLQA 

      1630       1640       1650       1660       1670       1680 
EVKINIRQTT SDSAIPIRLF ITNESGYYLD ISLYREVTDS RSGNIMFHSF GNKQGSLHGM 

      1690       1700       1710       1720       1730       1740 
LINTPYVTKD LLQAKRFQAQ SLGTTYVYDF PEMFRQALFK LWGSPEKYPK DILTYTELVL 

      1750       1760       1770       1780       1790       1800 
DSQGQLVEMN RLPGCNEVGM VAFKMRFKTP EYPEGRDAVV IGNDITFQIG SFGIGEDFLY 

      1810       1820       1830       1840       1850       1860 
LRASEMARTE GIPQIYLAAN SGARMGLAEE IKQIFQVAWV DPEDPHKGFR YLYLTPQDYT 

      1870       1880       1890       1900       1910       1920 
QISSQNSVHC KHIEDEGESR YVIVDVIGKD ANLGVENLRG SGMIAGEASL AYEKTVTISM 

      1930       1940       1950       1960       1970       1980 
VTCRALGIGA YLVRLGQRVI QVENSHIILT GAGALNKVLG REVYTSNNQL GGVQIMHTNG 

      1990       2000       2010       2020       2030       2040 
VSHVTVPDDF EGVCTILEWL SFIPKDNRSP VPITTPSDPI DREIEFTPTK APYDPRWMLA 

      2050       2060       2070       2080       2090       2100 
GRPHPTLKGT WQSGFFDHGS FKEIMAPWAQ TVVTGRARLG GIPVGVIAVE TRTVEVAVPA 

      2110       2120       2130       2140       2150       2160 
DPANLDSEAK IIQQAGQVWF PDSAYKTAQV IRDFNKERLP LMIFANWRGF SGGMKDMYEQ 

      2170       2180       2190       2200       2210       2220 
MLKFGAYIVD GLRLYEQPIL IYIPPCAELR GGSWVVLDST INPLCIEMYA DKESRGGVLE 

      2230       2240       2250       2260       2270       2280 
PEGTVEIKFR KKDLVKTIRR IDPVCKKLVG QLGKAQLPDK DRKELEGQLK AREELLLPIY 

      2290       2300       2310       2320       2330       2340 
HQVAVQFADL HDTPGHMLEK GIISDVLEWK TARTFFYWRL RRLLLEAQVK QEILRASPEL 

      2350       2360       2370       2380       2390       2400 
SHEHTQSMLR RWFVETEGAV KAYLWDSNQV VVQWLEQHWS AKDGLRSTIR ENINYLKRDS 

      2410       2420       2430       2440 
VLKTIQSLVQ EHPEVIMDCV AYLSQHLTPA ERIQVAQLLS TTESPASS 

« Hide

References

[1]"Alternative splicing in the mouse acetyl-CoA carboxylase 2 (ACC2) gene."
Mao J., Wakil S.J.
Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL AAS13686.1.
Tissue: Heart EMBL AAS13686.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY451394 mRNA. Translation: AAS13686.1.
RefSeqNP_598665.2. NM_133904.2.
UniGeneMm.81793.

3D structure databases

ProteinModelPortalQ6JIZ0.
SMRQ6JIZ0. Positions 229-749, 875-967, 1683-2409.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

MINTMINT-1859452.

PTM databases

PhosphoSiteQ6JIZ0.

Proteomic databases

PRIDEQ6JIZ0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID100705.
KEGGmmu:100705.

Organism-specific databases

CTD32.
MGIMGI:2140940. Acacb.

Phylogenomic databases

HOGENOMHOG000214115.
HOVERGENHBG005371.
InParanoidQ6JIZ0.
KOK11262.

Enzyme and pathway databases

BRENDA6.4.1.2. 244.

Gene expression databases

GenevestigatorQ6JIZ0.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
3.90.226.10. 3 hits.
InterProIPR013537. AcCoA_COase_cen.
IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR011764. Biotin_carboxylation_dom.
IPR005482. Biotin_COase_C.
IPR000089. Biotin_lipoyl.
IPR005481. CarbamoylP_synth_lsu_N.
IPR000022. Carboxyl_trans.
IPR005479. CbamoylP_synth_lsu-like_ATP-bd.
IPR029045. ClpP/crotonase-like_dom.
IPR011763. COA_CT_C.
IPR011762. COA_CT_N.
IPR016185. PreATP-grasp_dom.
IPR011054. Rudment_hybrid_motif.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamPF08326. ACC_central. 1 hit.
PF02785. Biotin_carb_C. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF01039. Carboxyl_trans. 1 hit.
PF00289. CPSase_L_chain. 1 hit.
PF02786. CPSase_L_D2. 1 hit.
[Graphical view]
SMARTSM00878. Biotin_carb_C. 1 hit.
[Graphical view]
SUPFAMSSF51230. SSF51230. 1 hit.
SSF51246. SSF51246. 1 hit.
SSF52096. SSF52096. 2 hits.
SSF52440. SSF52440. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS50979. BC. 1 hit.
PS50968. BIOTINYL_LIPOYL. 1 hit.
PS50989. COA_CT_CTER. 1 hit.
PS50980. COA_CT_NTER. 1 hit.
PS00866. CPSASE_1. 1 hit.
PS00867. CPSASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSACACB. mouse.
NextBio354598.
SOURCESearch...

Entry information

Entry nameQ6JIZ0_MOUSE
AccessionPrimary (citable) accession number: Q6JIZ0
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)