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Protein
Submitted name:

LMO7a

Gene

Lmo7

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. actinin binding Source: RGD
  2. protein C-terminus binding Source: RGD
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. regulation of cell adhesion Source: InterPro
  2. regulation of signaling Source: InterPro
  3. single organismal cell-cell adhesion Source: RGD
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
LMO7aImported
Gene namesi
Name:Lmo7Imported
Synonyms:LMO7Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi1302984. Lmo7.

Subcellular locationi

GO - Cellular componenti

  1. apical plasma membrane Source: RGD
  2. cell-cell adherens junction Source: RGD
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ6JBI7.

PTM databases

PhosphoSiteiQ6JBI7.

Expressioni

Gene expression databases

GenevestigatoriQ6JBI7.

Structurei

3D structure databases

ProteinModelPortaliQ6JBI7.
SMRiQ6JBI7. Positions 1064-1152.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 LIM zinc-binding domain.UniRule annotation
Contains 1 PDZ (DHR) domain.UniRule annotation

Keywords - Domaini

LIM domainUniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000043081.
HOVERGENiHBG049143.
KOiK06084.
PhylomeDBiQ6JBI7.

Family and domain databases

Gene3Di1.10.418.10. 1 hit.
2.10.110.10. 1 hit.
2.30.42.10. 1 hit.
InterProiIPR001715. CH-domain.
IPR029978. LMO-7.
IPR001478. PDZ.
IPR003096. SM22_calponin.
IPR001781. Znf_LIM.
[Graphical view]
PANTHERiPTHR15551:SF4. PTHR15551:SF4. 1 hit.
PfamiPF00307. CH. 1 hit.
PF00412. LIM. 1 hit.
PF00595. PDZ. 1 hit.
[Graphical view]
PRINTSiPR00888. SM22CALPONIN.
SMARTiSM00033. CH. 1 hit.
SM00132. LIM. 1 hit.
SM00228. PDZ. 1 hit.
[Graphical view]
SUPFAMiSSF47576. SSF47576. 1 hit.
SSF50156. SSF50156. 1 hit.
PROSITEiPS50021. CH. 1 hit.
PS00478. LIM_DOMAIN_1. 1 hit.
PS50023. LIM_DOMAIN_2. 1 hit.
PS50106. PDZ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6JBI7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGMEDAEAD CSIAFAEAQR WVEAVTEKNF ETRDFRASLE NGVLLCDLIN
60 70 80 90 100
KLKPGVVRKI NRLSTPIAGL DNINVFLKAC EQIGLKEAQL FHPGDLQDLS
110 120 130 140 150
NRVTVKQEET DRRLKNVLIT LYWLGRKAQN NPYYHGPYLN LKAFETLLGQ
160 170 180 190 200
ALTKALEDSS CLKRSGRDSG YGDIWCPDRG DFPAPPGSHR REDSFESLDS
210 220 230 240 250
LGSRSLTSCS SDLTLRGGRE GCESDNDWEF TFKMQDYNKD DMSYRRISAI
260 270 280 290 300
EPKSALPFNR FLPNKSKQPS YVPAPLRKKR PDKNEDNRRS WASPVYTETE
310 320 330 340 350
GTFSSTQRRA WGPKMENWHT VQETSTSSWC LEEEEEKVTR LPNVVKDDLY
360 370 380 390 400
VRKLSPVMPS PGSSFDQFLP KGWTPEDMNW KKIKRETYKP WYKEFQGLSQ
410 420 430 440 450
FLLLQALQTY SDDILSSETN VKLDPTSGPR LITRRKNFSP TPGYRAHDLE
460 470 480 490 500
PQSLDPDLEN DDFFVRKTRA FHANPCVLRA FEDFRRFSEP DDAVERDIIL
510 520 530 540 550
QCREGELVLP DLEKDDMIVR RIPAQKKEVP LSGAPDRYQP VPFPEPWTLP
560 570 580 590 600
PEIQAKFLSV LERTCPPKDK PSSCRVLVPS HRLKKDDMLT RKIQSWKLGT
610 620 630 640 650
AVPPISFRPG PCSEADLRKW EAIREASRLR HRKRLMVERL FQKIYGENGS
660 670 680 690 700
KSLSDVSAED VQSLRQLRYE EMQKIKSQLK EQDQKWQDDL AKWKDRRKSY
710 720 730 740 750
TSDLQKKKEE REEIEKQALE KSDRSSKTFR EMLQDRESQS STTTSRRRIY
760 770 780 790 800
SSDDILDDGV LPPTVTLSET SYQSERLEDK ARAHPAEMPK EDSTTFASRE
810 820 830 840 850
DGIAAEIPLA SHIPEERRQA PWPSAETRQA SSSSAESHQA SLPSTESDQA
860 870 880 890 900
RLPSAEPHQA SFSSAEPRQV PLVSAEPHQA SSFSSTEPHQ ASLSSALQRP
910 920 930 940 950
SSLSSSQQSW STRGESTRIS ASLPRSYQRS DTARLTSVVT ARPFGTSSRG
960 970 980 990 1000
ISSLPRSYTM DDGWIYNGDV EVVKREQHDS GRAAGMKPDS SHFILGSSSE
1010 1020 1030 1040 1050
KEVATGEDGA SLSSFVLPSS SSLSHDQAAS SKATFSSTSG LDSVSDSGEG
1060 1070 1080 1090 1100
RSSSLREVSR SPDQFSDMRI SINQTPGTKH DFGFTIKWDV SGISVASVEK
1110 1120 1130 1140 1150
GSPAEFSQLQ VDDEILAINN TKFSYKDTKK WEEAMANAQE TGNLVMDVRR
1160 1170 1180 1190 1200
YGKSGSPETK WIDTTSGIYS TEKSSSLSVT TDFSESLQSP YSESKEINGI
1210 1220 1230 1240 1250
HEGSNAFDSK ASESISLKNL KRRSQFFEQG SSDSVAPDLP VPTLSAPSRW
1260 1270 1280 1290 1300
AWDQEEERRR QERWQKEQDR LLQEKYQREQ EKLREEWQRA QQEAERENSK
1310 1320 1330 1340 1350
YLDEELMVLN SNSISLTSRE SVTASWEPSW SEGSKSLDRE GTRAGDEDRG
1360 1370 1380 1390 1400
QLEDDAVYED QSQKLQERLM LEHEKKRKEQ EAQEEELRKQ REAEAQARAE
1410 1420 1430 1440 1450
AEAQARAEAQ ARAEAQAQAE AEARKRAEAQ KLQAERERET SVKIYQYRRP
1460 1470 1480 1490 1500
IDSYDLPKRE EESSGLLPID RSKSRSTTEL NDPLIEKSGS SKYSDRIGTT
1510 1520 1530 1540 1550
SFSQRSSKKD QGPSEAELER QQILQEMRKK TSLHNDNSWI RQRSASVNKE
1560 1570 1580 1590 1600
PICLTGIMRR GESLDNLDSQ RPGSWRQSSW HSQPAGVYAS SSVQDFSRLP
1610 1620 1630 1640 1650
PQLLSTSNRA YMRNPSSAVP PLAGSVKTSP GSPSPRSHSP SMSQSGSQLR
1660 1670 1680 1690 1700
NRSVSGKRVC SYCNSILGKG AAMIIETLGL CYHLHCFKCV SCERDLGGSS
1710 1720
SGAEVRIRNH QLYCNDCYLR FKSGRPTAM
Length:1,729
Mass (Da):195,571
Last modified:July 5, 2004 - v1
Checksum:i7237E98173E2237A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY533473 mRNA. Translation: AAT02180.1.
RefSeqiNP_001001515.1. NM_001001515.1.
UniGeneiRn.98417.

Genome annotation databases

GeneIDi361084.
KEGGirno:361084.
UCSCiRGD:1302984. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY533473 mRNA. Translation: AAT02180.1.
RefSeqiNP_001001515.1. NM_001001515.1.
UniGeneiRn.98417.

3D structure databases

ProteinModelPortaliQ6JBI7.
SMRiQ6JBI7. Positions 1064-1152.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiQ6JBI7.

Proteomic databases

PRIDEiQ6JBI7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi361084.
KEGGirno:361084.
UCSCiRGD:1302984. rat.

Organism-specific databases

CTDi4008.
RGDi1302984. Lmo7.

Phylogenomic databases

HOGENOMiHOG000043081.
HOVERGENiHBG049143.
KOiK06084.
PhylomeDBiQ6JBI7.

Miscellaneous databases

NextBioi675156.

Gene expression databases

GenevestigatoriQ6JBI7.

Family and domain databases

Gene3Di1.10.418.10. 1 hit.
2.10.110.10. 1 hit.
2.30.42.10. 1 hit.
InterProiIPR001715. CH-domain.
IPR029978. LMO-7.
IPR001478. PDZ.
IPR003096. SM22_calponin.
IPR001781. Znf_LIM.
[Graphical view]
PANTHERiPTHR15551:SF4. PTHR15551:SF4. 1 hit.
PfamiPF00307. CH. 1 hit.
PF00412. LIM. 1 hit.
PF00595. PDZ. 1 hit.
[Graphical view]
PRINTSiPR00888. SM22CALPONIN.
SMARTiSM00033. CH. 1 hit.
SM00132. LIM. 1 hit.
SM00228. PDZ. 1 hit.
[Graphical view]
SUPFAMiSSF47576. SSF47576. 1 hit.
SSF50156. SSF50156. 1 hit.
PROSITEiPS50021. CH. 1 hit.
PS00478. LIM_DOMAIN_1. 1 hit.
PS50023. LIM_DOMAIN_2. 1 hit.
PS50106. PDZ. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Involvement of LMO7 in the association of two cell-cell adhesion molecules, nectin and E-cadherin, through afadin and alpha-actinin in epithelial cells."
    Ooshio T., Irie K., Morimoto K., Fukuhara A., Imai T., Takai Y.
    J. Biol. Chem. 279:31365-31373(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Sprague-DawleyImported.

Entry informationi

Entry nameiQ6JBI7_RAT
AccessioniPrimary (citable) accession number: Q6JBI7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 4, 2015
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.