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Q6J5J3 (GPD1_SACUV) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1

EC=1.1.1.8
Gene names
Name:GPD1
OrganismSaccharomyces uvarum (Yeast) (Saccharomyces bayanus var. uvarum)
Taxonomic identifier230603 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length391 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 391391Glycerol-3-phosphate dehydrogenase [NAD(+)] 1
PRO_0000138099

Regions

Nucleotide binding41 – 466NAD By similarity
Region310 – 3112Substrate binding By similarity

Sites

Active site2451Proton acceptor By similarity
Binding site1291NAD By similarity
Binding site1521NAD; via amide nitrogen By similarity
Binding site1521Substrate By similarity
Binding site1851NAD; via amide nitrogen By similarity
Binding site3101NAD By similarity
Binding site3391NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6J5J3 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: F5F1F7F111F707D1

FASTA39142,869
        10         20         30         40         50         60 
MSAAADRLNL TSGHLNAGRK RSSSSVSLKA AEKPFKVTVI GSGNWGTTIA KVVAENCKGY 

        70         80         90        100        110        120 
PEVFAPIVQM WVFEEEINGE KLTEIINTRH QNVKYLPGIT LPDNLVANPD LIDSVKDVDI 

       130        140        150        160        170        180 
IVFNIPHQFL PRICSQLKGH VDSHVRAISC LKGFEVGAKG VQLLSSYITE ELGIQCGALS 

       190        200        210        220        230        240 
GANIATEVAQ EHWSETTVAY HIPKDFRGEG KDVDHKVLKA LFHRPYFHVS VIEDVAGISI 

       250        260        270        280        290        300 
CGALKNVVAL GCGFVEGLGW GNNASAAIQR VGLGEIIRFG QMFFPESREE TYYQESAGVA 

       310        320        330        340        350        360 
DLITTCAGGR NVKVARLMAT SGKDAWECEK ELLNGQSAQG LITCKEVHEW LETCGSVEDF 

       370        380        390 
PLFEAVYQIV YNNYPMKNLP DMIEELDLHE D 

« Hide

References

[1]"Research on the mechanism of osmotolerance and thermotolerance of yeast."
Ma X., Guo Y., Zhang F., Yu H., Kuang J., Yao J., Li Z., He G.
Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: YY.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY598967 Genomic DNA. Translation: AAT27377.1.

3D structure databases

ProteinModelPortalQ6J5J3.
SMRQ6J5J3. Positions 33-385.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR11728. PTHR11728. 1 hit.
PfamPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSPR00077. GPDHDRGNASE.
SUPFAMSSF48179. SSF48179. 1 hit.
TIGRFAMsTIGR03376. glycerol3P_DH. 1 hit.
PROSITEPS00957. NAD_G3PDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGPD1_SACUV
AccessionPrimary (citable) accession number: Q6J5J3
Entry history
Integrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families