Q6J2K6 (BIP2C_ORYSI) Reviewed, UniProtKB/Swiss-Prot
Last modified
April 3, 2013.
Version 41.
History...
Clusters with 
Names·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Probable protein phosphatase 2C BIPP2C1 EC=3.1.3.16 Alternative name(s): BTH-induced protein phosphatase 2C 1 Short name=OsBIPP2C1 | ||
| Gene names |
| ||
| Organism | Oryza sativa subsp. indica (Rice) | ||
| Taxonomic identifier | 39946 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza ›  |
Protein attributes
| Sequence length | 569 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | May play a role in responses to biotic and abiotic stresses. Ref.1 |
| Catalytic activity | A phosphoprotein + H2O = a protein + phosphate. |
| Cofactor | Binds 2 magnesium or manganese ions per subunit By similarity. |
| Induction | By salicylic acid (SA), benzothiadiazole (BTH), hydrogen peroxide, abscisic acid (ABA), wounding, salt, cold and osmotic stresses. Ref.1 |
| Sequence similarities | Belongs to the PP2C family. Contains 1 PP2C-like domain. |
Ontologies
| Keywords | |
|---|---|
| Coding sequence diversity | Alternative splicing |
| Ligand | Magnesium Manganese Metal-binding |
| Molecular function | Hydrolase Protein phosphatase |
| Gene Ontology (GO) | |
| Biological_process | metabolic process Inferred from electronic annotation. Source: GOC |
| Molecular_function | metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoprotein phosphatase activityInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Alternative products
| This entry describes 4 isoforms produced by alternative splicing. [Align] [Select] | ||||||
| Isoform 1 (identifier: Q6J2K6-1) This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. | ||||||
| Isoform 2 (identifier: Q6J2K6-2) The sequence of this isoform differs from the canonical sequence as follows: 1-36: MDEEARAAGC...ELCLCSPTGV → MKRRAPPDAP...LVWFGVGLDA | ||||||
| Note: Derived from EST data. No experimental confirmation available. | ||||||
| Isoform 3 (identifier: Q6J2K6-3) The sequence of this isoform differs from the canonical sequence as follows: 35-36: Missing. | ||||||
| Note: Derived from EST data. May be due to a competing donor splice site. No experimental confirmation available. | ||||||
| Isoform 4 (identifier: Q6J2K6-4) The sequence of this isoform differs from the canonical sequence as follows: 121-256: Missing. | ||||||
| Note: Derived from EST data. No experimental confirmation available. |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 569 | 569 | Probable protein phosphatase 2C BIPP2C1 | PRO_0000363326 | |||||
Regions | |||||||||
| Domain | 327 – 564 | 238 | PP2C-like | ||||||
Sites | |||||||||
| Metal binding | 358 | 1 | Manganese 1 By similarity | ||||||
| Metal binding | 358 | 1 | Manganese 2 By similarity | ||||||
| Metal binding | 359 | 1 | Manganese 1; via carbonyl oxygen By similarity | ||||||
| Metal binding | 488 | 1 | Manganese 2 By similarity | ||||||
| Metal binding | 555 | 1 | Manganese 2 By similarity | ||||||
Natural variations | |||||||||
| Alternative sequence | 1 – 36 | 36 | MDEEA…SPTGV → MKRRAPPDAPQRRPARRLLP VALPPSSASAPLQVWVRGIH ACLISFGFGSRFDLVLVWFG VGLDA in isoform 2. | VSP_036283 | |||||
| Alternative sequence | 35 – 36 | 2 | Missing in isoform 3. | VSP_036284 | |||||
| Alternative sequence | 121 – 256 | 136 | Missing in isoform 4. | VSP_036285 | |||||
Sequences
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References
| [1] | "Molecular characterization and expression analysis of a rice protein phosphatase 2C gene, OsBIPP2C1, and overexpression in transgenic tobacco conferred enhanced disease resistance and abiotic tolerance." Hu X., Song F., Zheng Z. Physiol. Plantarum 127:225-236(2006) [AGRICOLA] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, INDUCTION. Strain: cv. Yuanfengzao. Tissue: Seedling. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AY603974 mRNA. Translation: AAT35116.1. |
3D structure databases | |
| ProteinModelPortal | Q6J2K6. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Organism-specific databases | |
| Gramene | Q6J2K6. |
Phylogenomic databases | |
| eggNOG | COG0631. |
| HOGENOM | HOG000077674. |
Gene expression databases | |
| ArrayExpress | Q6J2K6. |
Family and domain databases | |
| Gene3D | 3.60.40.10. 2 hits. |
| InterPro | IPR001932. PP2C-like. [Graphical view] |
| Pfam | PF07228. SpoIIE. 1 hit. [Graphical view] |
| SMART | SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view] |
| SUPFAM | SSF81606. PP2C-related. 1 hit. |
| PROSITE | PS01032. PP2C. False negative. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BIP2C_ORYSI | ||||||||
| Accession | Primary (citable) accession number: Q6J2K6 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Plant Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |