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Protein

Probable protein phosphatase 2C BIPP2C1

Gene

BIPP2C1

Organism
Oryza sativa subsp. indica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in responses to biotic and abiotic stresses.1 Publication

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi358Manganese 1By similarity1
Metal bindingi358Manganese 2By similarity1
Metal bindingi359Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi488Manganese 2By similarity1
Metal bindingi555Manganese 2By similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C BIPP2C1 (EC:3.1.3.16)
Alternative name(s):
BTH-induced protein phosphatase 2C 1
Short name:
OsBIPP2C1
Gene namesi
Name:BIPP2C1
OrganismiOryza sativa subsp. indica (Rice)
Taxonomic identifieri39946 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003633261 – 569Probable protein phosphatase 2C BIPP2C1Add BLAST569

Expressioni

Inductioni

By salicylic acid (SA), benzothiadiazole (BTH), hydrogen peroxide, abscisic acid (ABA), wounding, salt, cold and osmotic stresses.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi39946.BGIOSGA012028-PA.

Structurei

3D structure databases

ProteinModelPortaliQ6J2K6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini329 – 564PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST236

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1379. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000077674.

Family and domain databases

Gene3Di3.60.40.10. 2 hits.
InterProiIPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PfamiPF07228. SpoIIE. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q6J2K6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MDEEARAAGC SPAPPRAPAA SCGAAAELCL CSPTGVEGIE QVPGCPCFED
60 70 80 90 100
AGAVVVSGEA PEGPGVLCSG DGAELKLAEQ GALDVRLGSP AVGIHEQQLL
110 120 130 140 150
HRGTSGSDEA GAINEISPVE VSPSEASSNL DTAGAIGGSP LMLESLPETS
160 170 180 190 200
DTRGCEQEVM PGVVVGSSNR DASSEVGVES ECGSDADGRN GLGEGELVSS
210 220 230 240 250
VDGGGAEKSS KVTGVLSEEG VDGMETALEP CVASVGSITQ VEEGVDRMET
260 270 280 290 300
SLDDSEASDG STTQDFDTDV ETESSGSSIE EQDMGYGVHI PHTEQAICEV
310 320 330 340 350
ARGNKSSEVK SSDRMSSVTL PTLILASGAA MLPHPSKVLT GGEDAYFIAC
360 370 380 390 400
DGWFGVADGV GQWSFEGINA GLYARELMDG CKKAVMESQG APEMRTEEVL
410 420 430 440 450
AKAADEARSP GSSTVLVAHF DGQVLHACNI GDSGFLVIRN GEIYQKSKPM
460 470 480 490 500
TYGFNFPLQI EKGDDPFKLV QKYTIDLQEG DAIVTATDGL FDNVYEEEIA
510 520 530 540 550
AVISKSLEAG LKPSEIAEFL VARAKEVGRS ATCRSPFSDA ALAVGYLGYS
560
GGKLDDVTVV VSVVRKSEV
Length:569
Mass (Da):58,675
Last modified:July 5, 2004 - v1
Checksum:iDEC2D71CDF4363C6
GO
Isoform 2 (identifier: Q6J2K6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-36: MDEEARAAGC...ELCLCSPTGV → MKRRAPPDAP...LVWFGVGLDA

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:598
Mass (Da):62,365
Checksum:i9DB2668E8D557CE8
GO
Isoform 3 (identifier: Q6J2K6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     35-36: Missing.

Note: Derived from EST data. May be due to a competing donor splice site. No experimental confirmation available.
Show »
Length:567
Mass (Da):58,519
Checksum:i53A40403BECAF9FB
GO
Isoform 4 (identifier: Q6J2K6-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     121-256: Missing.

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:433
Mass (Da):45,107
Checksum:iF0974C7C7815B0EF
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0362831 – 36MDEEA…SPTGV → MKRRAPPDAPQRRPARRLLP VALPPSSASAPLQVWVRGIH ACLISFGFGSRFDLVLVWFG VGLDA in isoform 2. CuratedAdd BLAST36
Alternative sequenceiVSP_03628435 – 36Missing in isoform 3. Curated2
Alternative sequenceiVSP_036285121 – 256Missing in isoform 4. CuratedAdd BLAST136

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY603974 mRNA. Translation: AAT35116.1.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY603974 mRNA. Translation: AAT35116.1.

3D structure databases

ProteinModelPortaliQ6J2K6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39946.BGIOSGA012028-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG1379. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000077674.

Family and domain databases

Gene3Di3.60.40.10. 2 hits.
InterProiIPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PfamiPF07228. SpoIIE. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBIP2C_ORYSI
AccessioniPrimary (citable) accession number: Q6J2K6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: July 5, 2004
Last modified: February 17, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.