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Q6J2K6 (BIP2C_ORYSI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C BIPP2C1

EC=3.1.3.16
Alternative name(s):
BTH-induced protein phosphatase 2C 1
Short name=OsBIPP2C1
Gene names
Name:BIPP2C1
OrganismOryza sativa subsp. indica (Rice)
Taxonomic identifier39946 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length569 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May play a role in responses to biotic and abiotic stresses. Ref.1

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Induction

By salicylic acid (SA), benzothiadiazole (BTH), hydrogen peroxide, abscisic acid (ABA), wounding, salt, cold and osmotic stresses. Ref.1

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Ontologies

Keywords
   Coding sequence diversityAlternative splicing
   LigandMagnesium
Manganese
Metal-binding
   Molecular functionHydrolase
Protein phosphatase
Gene Ontology (GO)
   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q6J2K6-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q6J2K6-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-36: MDEEARAAGC...ELCLCSPTGV → MKRRAPPDAP...LVWFGVGLDA
Note: Derived from EST data. No experimental confirmation available.
Isoform 3 (identifier: Q6J2K6-3)

The sequence of this isoform differs from the canonical sequence as follows:
     35-36: Missing.
Note: Derived from EST data. May be due to a competing donor splice site. No experimental confirmation available.
Isoform 4 (identifier: Q6J2K6-4)

The sequence of this isoform differs from the canonical sequence as follows:
     121-256: Missing.
Note: Derived from EST data. No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 569569Probable protein phosphatase 2C BIPP2C1
PRO_0000363326

Regions

Domain327 – 564238PP2C-like

Sites

Metal binding3581Manganese 1 By similarity
Metal binding3581Manganese 2 By similarity
Metal binding3591Manganese 1; via carbonyl oxygen By similarity
Metal binding4881Manganese 2 By similarity
Metal binding5551Manganese 2 By similarity

Natural variations

Alternative sequence1 – 3636MDEEA…SPTGV → MKRRAPPDAPQRRPARRLLP VALPPSSASAPLQVWVRGIH ACLISFGFGSRFDLVLVWFG VGLDA in isoform 2.
VSP_036283
Alternative sequence35 – 362Missing in isoform 3.
VSP_036284
Alternative sequence121 – 256136Missing in isoform 4.
VSP_036285

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: DEC2D71CDF4363C6

FASTA56958,675
        10         20         30         40         50         60 
MDEEARAAGC SPAPPRAPAA SCGAAAELCL CSPTGVEGIE QVPGCPCFED AGAVVVSGEA 

        70         80         90        100        110        120 
PEGPGVLCSG DGAELKLAEQ GALDVRLGSP AVGIHEQQLL HRGTSGSDEA GAINEISPVE 

       130        140        150        160        170        180 
VSPSEASSNL DTAGAIGGSP LMLESLPETS DTRGCEQEVM PGVVVGSSNR DASSEVGVES 

       190        200        210        220        230        240 
ECGSDADGRN GLGEGELVSS VDGGGAEKSS KVTGVLSEEG VDGMETALEP CVASVGSITQ 

       250        260        270        280        290        300 
VEEGVDRMET SLDDSEASDG STTQDFDTDV ETESSGSSIE EQDMGYGVHI PHTEQAICEV 

       310        320        330        340        350        360 
ARGNKSSEVK SSDRMSSVTL PTLILASGAA MLPHPSKVLT GGEDAYFIAC DGWFGVADGV 

       370        380        390        400        410        420 
GQWSFEGINA GLYARELMDG CKKAVMESQG APEMRTEEVL AKAADEARSP GSSTVLVAHF 

       430        440        450        460        470        480 
DGQVLHACNI GDSGFLVIRN GEIYQKSKPM TYGFNFPLQI EKGDDPFKLV QKYTIDLQEG 

       490        500        510        520        530        540 
DAIVTATDGL FDNVYEEEIA AVISKSLEAG LKPSEIAEFL VARAKEVGRS ATCRSPFSDA 

       550        560 
ALAVGYLGYS GGKLDDVTVV VSVVRKSEV 

« Hide

Isoform 2 [UniParc].

Checksum: 9DB2668E8D557CE8
Show »

FASTA59862,365
Isoform 3 [UniParc].

Checksum: 53A40403BECAF9FB
Show »

FASTA56758,519
Isoform 4 [UniParc].

Checksum: F0974C7C7815B0EF
Show »

FASTA43345,107

References

[1]"Molecular characterization and expression analysis of a rice protein phosphatase 2C gene, OsBIPP2C1, and overexpression in transgenic tobacco conferred enhanced disease resistance and abiotic tolerance."
Hu X., Song F., Zheng Z.
Physiol. Plantarum 127:225-236(2006) [AGRICOLA] [Europe PMC]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, INDUCTION.
Strain: cv. Yuanfengzao.
Tissue: Seedling.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY603974 mRNA. Translation: AAT35116.1.

3D structure databases

ProteinModelPortalQ6J2K6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING39947.LOC_Os03g09220.1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GrameneQ6J2K6.

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000077674.

Family and domain databases

Gene3D3.60.40.10. 2 hits.
InterProIPR001932. PP2C-like_dom.
[Graphical view]
PfamPF07228. SpoIIE. 1 hit.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 1 hit.
ProtoNetSearch...

Entry information

Entry nameBIP2C_ORYSI
AccessionPrimary (citable) accession number: Q6J2K6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families