Unreviewed, UniProtKB/TrEMBL Q6IZD5 (Q6IZD5_CAEEL)

Names and origin

Protein names

Submitted name:
    Protein Y57G11C.24g, confirmed by transcript evidence EMBL CAJ44243.1
Submitted name:
    Epidermal growth factor receptor pathway substrate 8 splice variant A EMBL AAT37523.1

Gene names

Name:	eps-8 EMBL AAT37523.1 WormBase WBGene00001330 WormPep Y57G11C.24g
ORF Names:	Y57G11C.24 WormPep Y57G11C.24g, Y57G11C.24g EMBL CAJ44243.1

Organism

Caenorhabditis elegans [Complete proteome] EMBL AAT37523.1

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	917 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Molecular function	Receptor EMBL AAT37523.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	embryonic development ending in birth or egg hatching Ref.1 Inferred from mutant phenotype. Source: WormBase growth Inferred from mutant phenotype. Source: WormBase locomotion Inferred from mutant phenotype. Source: WormBase nematode larval development Ref.1 Inferred from mutant phenotype. Source: WormBase positive regulation of growth rate Inferred from mutant phenotype. Source: WormBase
Molecular function	receptor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6IZD5-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 4BC021037B43E170	FASTA	917	104,365
	10 20 30 40 50 60 MRRGGSMGPP SGDPYQSRPS PGGYYYNRST PGGQPAPSPS HSQQSASSHH PRGVPMSQPI 70 80 90 100 110 120 ARRSDYRTGS EQMTPRSDHR GPSMGYGNGG SVDQRVDDVT PSYYVEHLAT FAVGRQFGLT 130 140 150 160 170 180 FPADGIRKLK QMEKNSAIWA QPLILRFRHN AVTVEDDNGE LVEQFPLELI EQPTAHVSND 190 200 210 220 230 240 SRETYNNVLL FVVREDRKRM STPTEMHIFQ CIRVSATDVA EDLKNYVQGQ FRRVRNGRRT 250 260 270 280 290 300 AAPTHLQAQQ QQMPFYPPDD ASISSETSEM FERDVNTLNR CFDDIERFVA RIQSAALAQR 310 320 330 340 350 360 EIEQQNHRYR TANRRDKKNQ QPPDPNGILF MRAQLPLESE FVDILKKFKL SFNLLAKLKN 370 380 390 400 410 420 HIHEPNAPEL LHFLFTPLAV ILEACHWGLG RNVAPTVASP LLSLEARELM QNCLTSHESD 430 440 450 460 470 480 IWMSLGEAWR TPPEDWTKPL PPPYRPIFND GFAPYGVADR AMATPNQIHR GHSAPPEHFR 490 500 510 520 530 540 QPPPRERNMV DTLEFDRLTL ERERLEFEKA KIMERESRLR HEEKQIEDEK RRMHAEKDLI 550 560 570 580 590 600 TKETTQPVPP PAAVVTHQPI TKRYDPPISI SPPPQRNNYS HVKVTVDSDT SPRQQAFIDD 610 620 630 640 650 660 IVAKGGKLAV VTYDRGGQNT KELTVHKGEY LEVIFDERNW WECKNMHQRV GYVPHTILSM 670 680 690 700 710 720 VPFEQQQYAS PNHHNNSSST GGYNNGHHQG PAQNVYRPPP PPLVSDAGVQ VEIRREHVAP 730 740 750 760 770 780 PPPPVVIPPP PPPVRTPTME ELLRMQQQQQ QKQRKPPVEE PVYQPQPAQR AGLEIWRRNQ 790 800 810 820 830 840 NPQLIQEVTE TVGQHSGDIL RPAMQRATRV AINEKSSPED VTRWLQEKGF SPRVIDLLDG 850 860 870 880 890 900 QDGANLFSLS KLHLQQACGR DEGGYLYSQL LVQKKRSGFR THTGDELKAI LNHRRTHVEL 910 SNEAAADEPV FTINPIL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A novel actin barbed-end-capping activity in EPS-8 regulates apical morphogenesis in intestinal cells of Caenorhabditis elegans." Croce A., Cassata G., Disanza A., Gagliani M.C., Tacchetti C., Malabarba M.G., Carlier M.F., Scita G., Baumeister R., Di Fiore P.P. Nat. Cell Biol. 6:1173-1179(2004) [PubMed: 15558032] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: N2 EMBL AAT37523.1.
[2]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY611484 mRNA. Translation: AAT37523.1. Z99281 Genomic DNA. Translation: CAJ44243.1.
RefSeq	NP_001041047.1.
UniGene	Cel.17206
3D structure databases
HSSP	HSSP built from PDB template 1AOJ based on UniProtKB Q08509.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q6IZD5. 8 interactions.
STRING	Q6IZD5.
Genome annotation databases
Ensembl	Y57G11C.24g; Y57G11C.24g; Y57G11C.24; Caenorhabditis elegans. [Genome view]
GeneID	178411.
UCSC	Y57G11C.24g. c. elegans.
Organism-specific databases
CTD	178411.
WormBase	WBGene00001330. eps-8.
WormPep	Y57G11C.24g. CE39450. [WorfDB]
Phylogenomic databases
InParanoid	Q6IZD5.
OMA	RHEEKQI.
PhylomeDB	Q6IZD5.
Gene expression databases
ArrayExpress	Q6IZD5.
Family and domain databases
InterPro	IPR013625. PTB. IPR006020. PTB_PID. IPR010993. SAM_homology. IPR011511. SH3_2. IPR001452. SH3_domain. [Graphical view]
Pfam	PF08416. PTB. 1 hit. PF07653. SH3_2. 1 hit. [Graphical view]
SMART	SM00462. PTB. 1 hit. SM00326. SH3. 1 hit. [Graphical view]
PROSITE	PS50002. SH3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6IZD5_CAEEL

Accession

Primary (citable) accession number: Q6IZD5

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 15, 2009
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)