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Protein

Succinate receptor 1

Gene

Sucnr1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Receptor for succinate.1 Publication

GO - Molecular functioni

  • G-protein coupled receptor activity Source: RGD

GO - Biological processi

  • G-protein coupled receptor signaling pathway Source: RGD
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Succinate receptor 1
Alternative name(s):
G-protein coupled receptor 91
Gene namesi
Name:Sucnr1
Synonyms:Gpr91
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1303193. Sucnr1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 27ExtracellularSequence analysisAdd BLAST27
Transmembranei28 – 48Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini49 – 55CytoplasmicSequence analysis7
Transmembranei56 – 76Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini77 – 99ExtracellularSequence analysisAdd BLAST23
Transmembranei100 – 120Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini121 – 133CytoplasmicSequence analysisAdd BLAST13
Transmembranei134 – 154Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini155 – 181ExtracellularSequence analysisAdd BLAST27
Transmembranei182 – 202Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini203 – 226CytoplasmicSequence analysisAdd BLAST24
Transmembranei227 – 247Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini248 – 276ExtracellularSequence analysisAdd BLAST29
Transmembranei277 – 297Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini298 – 317CytoplasmicSequence analysisAdd BLAST20

GO - Cellular componenti

  • integral component of membrane Source: RGD
  • plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL2150839.
GuidetoPHARMACOLOGYi166.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003835941 – 317Succinate receptor 1Add BLAST317

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi4N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi91 ↔ 168PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ6IYF9.

PTM databases

PhosphoSitePlusiQ6IYF9.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000018767.

Chemistry databases

BindingDBiQ6IYF9.

Structurei

3D structure databases

ProteinModelPortaliQ6IYF9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IJKI. Eukaryota.
ENOG410YANU. LUCA.
HOGENOMiHOG000231307.
InParanoidiQ6IYF9.
KOiK10042.
PhylomeDBiQ6IYF9.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6IYF9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQNLSCENW LALENILKKY YLSAFYGIEF IVGMLGNFTV VFGYLFCMKN
60 70 80 90 100
WNSSNVYLFN LSISDLAFLC TLPMLIRSYA TGNWTYGDVL CISNRYVLHA
110 120 130 140 150
NLYTSILFLT FISIDRYLLM KFPFREHILQ KKEFAILISL AVWVLVTLEV
160 170 180 190 200
LPMLTFITST PIEKGDSCVD YASSGNPKYS LIYSLCLTLL GFLIPLSVMC
210 220 230 240 250
FFYYKMVVFL KKRSQQQATV LSLNKPLRLV VLAVVIFSVL FTPYHIMRNV
260 270 280 290 300
RIASRLDSWP QGCSQKAIKC LYILTRPLAF LNSAVNPIFY FLVGDHFRDM
310
LFSKLRQYFK SLTSFRL
Length:317
Mass (Da):36,679
Last modified:July 5, 2004 - v1
Checksum:i5971EFB7ABF6113B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY612851 mRNA. Translation: AAT10590.1.
RefSeqiNP_001001518.1. NM_001001518.1.
UniGeneiRn.124512.

Genome annotation databases

GeneIDi408199.
KEGGirno:408199.
UCSCiRGD:1303193. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY612851 mRNA. Translation: AAT10590.1.
RefSeqiNP_001001518.1. NM_001001518.1.
UniGeneiRn.124512.

3D structure databases

ProteinModelPortaliQ6IYF9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000018767.

Chemistry databases

BindingDBiQ6IYF9.
ChEMBLiCHEMBL2150839.
GuidetoPHARMACOLOGYi166.

Protein family/group databases

GPCRDBiSearch...

PTM databases

PhosphoSitePlusiQ6IYF9.

Proteomic databases

PaxDbiQ6IYF9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi408199.
KEGGirno:408199.
UCSCiRGD:1303193. rat.

Organism-specific databases

CTDi56670.
RGDi1303193. Sucnr1.

Phylogenomic databases

eggNOGiENOG410IJKI. Eukaryota.
ENOG410YANU. LUCA.
HOGENOMiHOG000231307.
InParanoidiQ6IYF9.
KOiK10042.
PhylomeDBiQ6IYF9.

Miscellaneous databases

PROiQ6IYF9.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSUCR1_RAT
AccessioniPrimary (citable) accession number: Q6IYF9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.