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Protein
Submitted name:

Gas6 protein

Gene

Gas6

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Gas6 proteinImported
Gene namesi
Name:Gas6Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi61913 Gas6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_500427592528 – 674Sequence analysisAdd BLAST647

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi122 ↔ 139PROSITE-ProRule annotation
Disulfide bondi141 ↔ 150PROSITE-ProRule annotation
Disulfide bondi639 ↔ 666PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PRIDEiQ6IRL1

Expressioni

Gene expression databases

GenevisibleiQ6IRL1 RN

Structurei

3D structure databases

ProteinModelPortaliQ6IRL1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 91GlaInterPro annotationAdd BLAST47
Domaini113 – 151EGF-likeInterPro annotationAdd BLAST39
Domaini153 – 193EGF-likeInterPro annotationAdd BLAST41
Domaini194 – 234EGF-likeInterPro annotationAdd BLAST41
Domaini235 – 275EGF-likeInterPro annotationAdd BLAST41
Domaini295 – 467LAM_G_DOMAINInterPro annotationAdd BLAST173
Domaini481 – 666LAM_G_DOMAINInterPro annotationAdd BLAST186

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IGK1 Eukaryota
ENOG410ZPM2 LUCA
HOVERGENiHBG051702
KOiK05464

Family and domain databases

Gene3Di4.10.740.10, 1 hit
InterProiView protein in InterPro
IPR017857 Coagulation_fac-like_Gla_dom
IPR013320 ConA-like_dom_sf
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR035972 GLA-like_dom_SF
IPR000294 GLA_domain
IPR009030 Growth_fac_rcpt_cys_sf
IPR001791 Laminin_G
PfamiView protein in Pfam
PF07645 EGF_CA, 2 hits
PF00594 Gla, 1 hit
PF00054 Laminin_G_1, 1 hit
PF02210 Laminin_G_2, 1 hit
PRINTSiPR00001 GLABLOOD
SMARTiView protein in SMART
SM00181 EGF, 4 hits
SM00179 EGF_CA, 4 hits
SM00069 GLA, 1 hit
SM00282 LamG, 2 hits
SUPFAMiSSF49899 SSF49899, 2 hits
SSF57184 SSF57184, 1 hit
SSF57630 SSF57630, 1 hit
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 4 hits
PS00022 EGF_1, 1 hit
PS01186 EGF_2, 3 hits
PS50026 EGF_3, 4 hits
PS01187 EGF_CA, 2 hits
PS00011 GLA_1, 1 hit
PS50998 GLA_2, 1 hit
PS50025 LAM_G_DOMAIN, 2 hits

Sequencei

Sequence statusi: Complete.

Q6IRL1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPPPGPTAA LGTALLLLLL ASESSHTVLL RAREAAQFLR PRQRRAYQVF
60 70 80 90 100
EEAKQGHLER ECVEEVCSKE EAREVFENDP ETDYFYPRYQ ECMRKYGRPE
110 120 130 140 150
DKNPNFATCV KNLPDQCTPN PCDKKGTQLC QDLMGNFFCL CKDGWGGRLC
160 170 180 190 200
DKDVNECSQK NGGCSQVCHN KPGSFQCACH SGFSLQSDNK SCQDIDECTD
210 220 230 240 250
SDTCGDARCK NLPGSYSCLC DKGYTYSSKE KTCQDVDECQ QDRCEQTCVN
260 270 280 290 300
SPGSYTCHCN GRGGLKLSPD MDTCEDILPC VPFSMAKSVK SLYLGRMFSG
310 320 330 340 350
TPVIRLRFKR LQPTRLLAEF DFRTFDPEGV LFFAGGRSDS TWIVLGFRAG
360 370 380 390 400
RLELQLRYNG VGRITSSGPT INHGMWQTIS VEELDRNLVI KVNKDAVMKI
410 420 430 440 450
AVAGGLFQLE RGLYHLNLTV GGIPFKESDL VQPINPRLDG CMRSWNWLNG
460 470 480 490 500
EDSAIQETVK ANTKMQCFSV TERGSFFPGN GFAFYSLNYT RTSLDVGTET
510 520 530 540 550
TWEVEVVARI RPATDTGVLM ALVGDKDVVL LSVALVDYHS TKKLKKQLVV
560 570 580 590 600
LAVENVALAL MEIKVCDSQE HTVTVSLRDG EATLEVDGTK GQSEVSTAQL
610 620 630 640 650
QERLDLLKTR LQGSVLTFVG GLPDVQVTST PVTAFYRGCM TLEVNGKTLD
660 670
LDTASYKHSD ITSHSCPPVE HVTA
Length:674
Mass (Da):74,672
Last modified:July 5, 2004 - v1
Checksum:iCC9A5EBD04480AE7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC070881 mRNA Translation: AAH70881.1
RefSeqiNP_476441.2, NM_057100.2
UniGeneiRn.52228

Genome annotation databases

GeneIDi58935
KEGGirno:58935

Similar proteinsi

Entry informationi

Entry nameiQ6IRL1_RAT
AccessioniPrimary (citable) accession number: Q6IRL1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health