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Protein
Submitted name:

Chemokine (C-X3-C motif) ligand 1

Gene

Cx3cl1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-380108. Chemokine receptors bind chemokines.

Names & Taxonomyi

Protein namesi
Submitted name:
Chemokine (C-X3-C motif) ligand 1Imported
Submitted name:
Cx3cl1 proteinImported
Submitted name:
FractalkineImported
Gene namesi
Name:Cx3cl1Imported
ORF Names:rCG_39059Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 19

Organism-specific databases

RGDi620458. Cx3cl1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei338 – 358HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501110096425 – 393Sequence analysisAdd BLAST369

Expressioni

Gene expression databases

BgeeiENSRNOG00000016326.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 89SCYInterPro annotationAdd BLAST61

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IJQZ. Eukaryota.
ENOG41116BY. LUCA.
GeneTreeiENSGT00510000049483.
HOVERGENiHBG057269.
OMAiYQSLQGC.
OrthoDBiEOG091G0WNR.
TreeFamiTF337534.

Family and domain databases

CDDicd00274. Chemokine_CX3C. 1 hit.
InterProiView protein in InterPro
IPR034127. Chemokine_CX3C.
IPR001811. Chemokine_IL8-like_dom.
IPR008097. CX3CL1.
IPR036048. Interleukin_8-like_sf.
PANTHERiPTHR12015:SF92. PTHR12015:SF92. 1 hit.
PfamiView protein in Pfam
PF00048. IL8. 1 hit.
SMARTiView protein in SMART
SM00199. SCY. 1 hit.
SUPFAMiSSF54117. SSF54117. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6IRF7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPSQLAWLL RLAAFFHLCT LLAGQHLGMT KCNITCHKMT SPIPVTLLIH
60 70 80 90 100
YQLNQESCGK RAIILETRQH RHFCADPKEK WVQDAMKHLD HQTAALTRNG
110 120 130 140 150
GKFEKRVDNV TPRITSTTRG LSPTALAKPE SATVEDLTLE PTAISQEARR
160 170 180 190 200
PMGTSQEPPA AVTGSFPSTS KAQDAGLAAK PQSTGISEVA AVSTTIWPSS
210 220 230 240 250
AVYQSGSSLW AEEKATESPP TIALSTQVST TSSPKQNVGS EGQPPWVQEQ
260 270 280 290 300
DSTPEKSPGP EETNPVHTDI FQDRGPGSTV HPSVAPTSSE KTPSPELVAS
310 320 330 340 350
GSQAPKVEEP IHATADPQKL SVFITPVPDS QAATRRQAVG LLAFLGLLFC
360 370 380 390
LGVAMFAYQS LQGCPRKMAG EMVEGLRYVP RSCGSNSYVL VPV
Length:393
Mass (Da):42,095
Last modified:July 5, 2004 - v1
Checksum:iF8FCBFE9C498C1B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC096512 Genomic DNA. No translation available.
BC070938 mRNA. Translation: AAH70938.1.
CH474006 Genomic DNA. Translation: EDL87326.1.
RefSeqiXP_008770551.1. XM_008772329.2.
UniGeneiRn.107266.

Genome annotation databases

EnsembliENSRNOT00000022128; ENSRNOP00000022128; ENSRNOG00000016326.
GeneIDi89808.

Similar proteinsi

Entry informationi

Entry nameiQ6IRF7_RAT
AccessioniPrimary (citable) accession number: Q6IRF7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 25, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported