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Protein
Submitted name:

MGC78846 protein

Gene

dgcr8

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
MGC78846 proteinImported
Gene namesi
Name:dgcr8Imported
Synonyms:MGC78846Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-976038. dgcr8.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4E5RX-ray1.90A300-355[»]
ProteinModelPortaliQ6IRB5.
SMRiQ6IRB5. Positions 491-700.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG051344.

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
InterProiIPR014720. dsRNA-bd_dom.
IPR001202. WW_dom.
[Graphical view]
PfamiPF00035. dsrm. 2 hits.
[Graphical view]
SMARTiSM00358. DSRM. 2 hits.
SM00456. WW. 1 hit.
[Graphical view]
SUPFAMiSSF51045. SSF51045. 1 hit.
PROSITEiPS50137. DS_RBD. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6IRB5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEECEEVAPF PEVNGHDVTE MNPASPPPLP PEEEPPPPPL QTSSDAEVMD
60 70 80 90 100
VGSGGDGQSQ TPAGDLQQNN GLQLFTKGST SYKSHRTVLD PFHSDQSPRT
110 120 130 140 150
ARHAPSNKRF TPDLKLLKDV KVSVSFTESC RSKDRHVLYT GLECEGSLHG
160 170 180 190 200
GSNMNSVNGD MYVCPFAGSS NGNVTDSIEI TLKKNYEPEI EQEKKVEYAV
210 220 230 240 250
LDELEDFTEN VMDVDEDGAE FVSESILQRE KIDEEALIYS YEDEFDNDVD
260 270 280 290 300
ALLEESLHTP KKRRIDEKYD IDSDHQSDGE SSVQPMVTKI KTVLKSRGRP
310 320 330 340 350
PTEPLPDGWI MTFHNSGLPV YLHRETRVVT WSRPYFLGTG SIRKHDPPIS
360 370 380 390 400
SIPCLHYKKM KDNDIKEQSN DVTSALVSVS SSTKSSDTSH NSEEPDTTAA
410 420 430 440 450
DSFVSDERES VSEVAQGALG QVKAKVEVCK DESINLEDFR SYLEKRFDFE
460 470 480 490 500
QVTVKKFRTW AERRQFNREM KRKQAECERP ILPANQKLIT LSVQDAPTKK
510 520 530 540 550
EFVINPNGKS EVCILHEYMQ RVLKVRPVYN FFECENPSEP FGASVIINGV
560 570 580 590 600
TYGTGTASSK KLAKNKAARA TLEILIPDFV KQTCIEKPKD TDELEYFNHI
610 620 630 640 650
SIEDSRVYEL TNKAGLLSPY QILHECLKRN HGMGDTSIKF EVIPGKNQKS
660 670 680 690 700
EYVMTCGKHT VRGWCKNKRV GKQLASQKIL QLLHPHVKNW GSLLRMYGRE
710 720 730 740 750
NSKIVKQETA DKSVIELQQF AKKNKPNLHI LNKLQEEMRR LAQEREETRK
760 770
KPKMTIVESA QPGSEPLCTV DV
Length:772
Mass (Da):87,193
Last modified:July 5, 2004 - v1
Checksum:i4E80583B7E05BA29
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC070985 mRNA. Translation: AAH70985.1.
RefSeqiNP_001085043.1. NM_001091574.1.
UniGeneiXl.19878.

Genome annotation databases

GeneIDi432110.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC070985 mRNA. Translation: AAH70985.1.
RefSeqiNP_001085043.1. NM_001091574.1.
UniGeneiXl.19878.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4E5RX-ray1.90A300-355[»]
ProteinModelPortaliQ6IRB5.
SMRiQ6IRB5. Positions 491-700.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi432110.

Organism-specific databases

CTDi54487.
XenbaseiXB-GENE-976038. dgcr8.

Phylogenomic databases

HOVERGENiHBG051344.

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
InterProiIPR014720. dsRNA-bd_dom.
IPR001202. WW_dom.
[Graphical view]
PfamiPF00035. dsrm. 2 hits.
[Graphical view]
SMARTiSM00358. DSRM. 2 hits.
SM00456. WW. 1 hit.
[Graphical view]
SUPFAMiSSF51045. SSF51045. 1 hit.
PROSITEiPS50137. DS_RBD. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: EmbryoImported.
  2. "Dimerization and heme binding are conserved in amphibian and starfish homologues of the microRNA processing protein DGCR8."
    Senturia R., Laganowsky A., Barr I., Scheidemantle B.D., Guo F.
    PLoS ONE 7:e39688-e39688(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 300-355.

Entry informationi

Entry nameiQ6IRB5_XENLA
AccessioniPrimary (citable) accession number: Q6IRB5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 27, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.