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Q6IRB5 (Q6IRB5_XENLA) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
MGC78846 protein EMBL AAH70985.1
Gene names
Name:dgcr8 Xenbase XB-GENE-976038
Synonyms:MGC78846 EMBL AAH70985.1
OrganismXenopus laevis (African clawed frog) EMBL AAH70985.1
Taxonomic identifier8355 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length772 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Ontologies

Keywords
   Technical term3D-structure PDB 4E5R
Gene Ontology (GO)
   Molecular_functiondouble-stranded RNA binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q6IRB5 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 4E80583B7E05BA29

FASTA77287,193
        10         20         30         40         50         60 
MEECEEVAPF PEVNGHDVTE MNPASPPPLP PEEEPPPPPL QTSSDAEVMD VGSGGDGQSQ 

        70         80         90        100        110        120 
TPAGDLQQNN GLQLFTKGST SYKSHRTVLD PFHSDQSPRT ARHAPSNKRF TPDLKLLKDV 

       130        140        150        160        170        180 
KVSVSFTESC RSKDRHVLYT GLECEGSLHG GSNMNSVNGD MYVCPFAGSS NGNVTDSIEI 

       190        200        210        220        230        240 
TLKKNYEPEI EQEKKVEYAV LDELEDFTEN VMDVDEDGAE FVSESILQRE KIDEEALIYS 

       250        260        270        280        290        300 
YEDEFDNDVD ALLEESLHTP KKRRIDEKYD IDSDHQSDGE SSVQPMVTKI KTVLKSRGRP 

       310        320        330        340        350        360 
PTEPLPDGWI MTFHNSGLPV YLHRETRVVT WSRPYFLGTG SIRKHDPPIS SIPCLHYKKM 

       370        380        390        400        410        420 
KDNDIKEQSN DVTSALVSVS SSTKSSDTSH NSEEPDTTAA DSFVSDERES VSEVAQGALG 

       430        440        450        460        470        480 
QVKAKVEVCK DESINLEDFR SYLEKRFDFE QVTVKKFRTW AERRQFNREM KRKQAECERP 

       490        500        510        520        530        540 
ILPANQKLIT LSVQDAPTKK EFVINPNGKS EVCILHEYMQ RVLKVRPVYN FFECENPSEP 

       550        560        570        580        590        600 
FGASVIINGV TYGTGTASSK KLAKNKAARA TLEILIPDFV KQTCIEKPKD TDELEYFNHI 

       610        620        630        640        650        660 
SIEDSRVYEL TNKAGLLSPY QILHECLKRN HGMGDTSIKF EVIPGKNQKS EYVMTCGKHT 

       670        680        690        700        710        720 
VRGWCKNKRV GKQLASQKIL QLLHPHVKNW GSLLRMYGRE NSKIVKQETA DKSVIELQQF 

       730        740        750        760        770 
AKKNKPNLHI LNKLQEEMRR LAQEREETRK KPKMTIVESA QPGSEPLCTV DV

« Hide

References

« Hide 'large scale' references
[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Embryo EMBL AAH70985.1.
[2]"Dimerization and heme binding are conserved in amphibian and starfish homologues of the microRNA processing protein DGCR8."
Senturia R., Laganowsky A., Barr I., Scheidemantle B.D., Guo F.
PLoS ONE 7:e39688-e39688(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 300-355.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC070985 mRNA. Translation: AAH70985.1.
RefSeqNP_001085043.1. NM_001091574.1.
UniGeneXl.19878.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4E5RX-ray1.90A300-355[»]
ProteinModelPortalQ6IRB5.
SMRQ6IRB5. Positions 491-700.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID432110.
KEGGxla:432110.

Organism-specific databases

CTD54487.
XenbaseXB-GENE-976038. dgcr8.

Phylogenomic databases

HOVERGENHBG051344.

Family and domain databases

Gene3D3.30.160.20. 1 hit.
InterProIPR001159. Ds-RNA-bd.
IPR014720. dsRNA-bd-like_dom.
IPR001202. WW_dom.
[Graphical view]
PfamPF00035. dsrm. 2 hits.
[Graphical view]
SMARTSM00358. DSRM. 2 hits.
SM00456. WW. 1 hit.
[Graphical view]
SUPFAMSSF51045. WW_Rsp5_WWP. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6IRB5_XENLA
AccessionPrimary (citable) accession number: Q6IRB5
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 1, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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