Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

PTPN9 protein

Gene

PTPN9

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei505Phosphocysteine intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphataseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
PTPN9 proteinImported
Gene namesi
Name:PTPN9Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiQ6IQ43
PRIDEiQ6IQ43

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

IntActiQ6IQ43, 5 interactors

Structurei

3D structure databases

ProteinModelPortaliQ6IQ43
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini74 – 233CRAL-TRIOInterPro annotationAdd BLAST160
Domaini293 – 564Tyrosine-protein phosphataseInterPro annotationAdd BLAST272
Domaini471 – 555TYR_PHOSPHATASE_2InterPro annotationAdd BLAST85

Phylogenomic databases

eggNOGiENOG410IF2N Eukaryota
COG5599 LUCA
HOVERGENiHBG006880
KOiK18038

Family and domain databases

CDDicd00170 SEC14, 1 hit
Gene3Di3.40.525.10, 1 hit
3.90.190.10, 1 hit
InterProiView protein in InterPro
IPR001251 CRAL-TRIO_dom
IPR036865 CRAL-TRIO_dom_sf
IPR011074 CRAL/TRIO_N_dom
IPR036273 CRAL/TRIO_N_dom_sf
IPR029021 Prot-tyrosine_phosphatase-like
IPR000242 PTPase_domain
IPR016130 Tyr_Pase_AS
IPR003595 Tyr_Pase_cat
IPR000387 TYR_PHOSPHATASE_dom
PfamiView protein in Pfam
PF00650 CRAL_TRIO, 1 hit
PF00102 Y_phosphatase, 1 hit
PRINTSiPR00700 PRTYPHPHTASE
SMARTiView protein in SMART
SM01100 CRAL_TRIO_N, 1 hit
SM00194 PTPc, 1 hit
SM00404 PTPc_motif, 1 hit
SM00516 SEC14, 1 hit
SUPFAMiSSF46938 SSF46938, 1 hit
SSF52087 SSF52087, 1 hit
SSF52799 SSF52799, 1 hit
PROSITEiView protein in PROSITE
PS50191 CRAL_TRIO, 1 hit
PS00383 TYR_PHOSPHATASE_1, 1 hit
PS50056 TYR_PHOSPHATASE_2, 1 hit
PS50055 TYR_PHOSPHATASE_PTP, 1 hit

Sequencei

Sequence statusi: Complete.

Q6IQ43-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPELTPEEE QATKQFLEEI NKWTVQYNVS PLSWNVAVKF LMARKFDVLR
60 70 80 90 100
AIELFHSYRE TRRKEGIVKL KPHEEPLRSE ILSGKFTILN VRDPTGASIA
110 120 130 140 150
LFTARLHHPH KSVQHVVLQA LFYLLDRAVD SFETQRNGLV FIYDMCGSNY
160 170 180 190 200
ADFELDLGKK VLNLLKGAFP ARLKKVLIVG APIWFRVPYS IISLLLKDKV
210 220 230 240 250
RERIQILKTS EVTQHLPREC LPENLGGYVK IDLATWNFQF LPQVNGHPDR
260 270 280 290 300
FDEIILFSLP PALDWDSVHV PGPHAMTIQE LVDYVNARQK QGIYEEYEDI
310 320 330 340 350
RRENPVGTFH CSMSPGNLEK NRYGDVPCLD QTRVKLTKRS GHTQTDYINA
360 370 380 390 400
SFMDGYKQKN AYIGTQGPLE NTYRDFWLMV WEQKVLVIVM TTRFEEGGRR
410 420 430 440 450
KCGQYWPLEK DSRIRFGFLT VTNLGVENMN HYKKTTLEIH NTEERQKRQV
460 470 480 490 500
THFQFLSWPD YGVPSSAASL IDFLRVVRNQ QSLAVSNMGA RSKGQCPEPP
510 520 530 540 550
IVVHCSAGIG RTGTFCSLDI CLAQLEELGT LNVFQTVSRM RTQRAFSIQT
560 570 580
PEQYYFCYKA ILEFAEKEGM VSSGQNLLAV ESQ
Length:583
Mass (Da):67,014
Last modified:July 5, 2004 - v1
Checksum:i81F9923FFF2852A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC071574 mRNA Translation: AAH71574.1
RefSeqiNP_002824.1, NM_002833.3
UniGeneiHs.445775

Genome annotation databases

GeneIDi5780
KEGGihsa:5780

Similar proteinsi

Entry informationi

Entry nameiQ6IQ43_HUMAN
AccessioniPrimary (citable) accession number: Q6IQ43
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health