Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Carboxylic ester hydrolase

Gene

CES2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation

Protein family/group databases

ESTHERihuman-CES2. Carb_B_Chordata.

Names & Taxonomyi

Protein namesi
Recommended name:
Carboxylic ester hydrolaseUniRule annotation (EC:3.1.1.-UniRule annotation)
Gene namesi
Name:CES2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  • extracellular exosome Source: UniProtKB

PTM / Processingi

Proteomic databases

PaxDbiQ6IPK9.
PeptideAtlasiQ6IPK9.

Expressioni

Gene expression databases

BgeeiENSG00000172831.

Structurei

3D structure databases

ProteinModelPortaliQ6IPK9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini74 – 565COesteraseInterPro annotationAdd BLAST492

Sequence similaritiesi

Belongs to the type-B carboxylesterase/lipase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1516. Eukaryota.
COG2272. LUCA.
HOVERGENiHBG008839.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiView protein in InterPro
IPR029058. AB_hydrolase.
IPR002018. CarbesteraseB.
IPR019826. Carboxylesterase_B_AS.
IPR019819. Carboxylesterase_B_CS.
PfamiView protein in Pfam
PF00135. COesterase. 1 hit.
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiView protein in PROSITE
PS00122. CARBOXYLESTERASE_B_1. 1 hit.
PS00941. CARBOXYLESTERASE_B_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q6IPK9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LTPCPVQTPR LGKALIHCWT DPGQPLGEQQ RVRRQRTETS EPTMRLHRLR
60 70 80 90 100
ARLSAVACGL LLLLVRGQGQ DSASPIRTTH TGQVLGSLVH VKGANAGVQT
110 120 130 140 150
FLGIPFAKPP LGPLRFAPPE PPESWSGVRD GTTHPAMCLQ DLTAVESEFL
160 170 180 190 200
SQFNMTFPSD SMSEDCLYLS IYTPAHSHEG SNLPVMVWIH GGALVFGMAS
210 220 230 240 250
LYDGSMLAAL ENVVVVIIQY RLGVLGFFST GDKHATGNWG YLDQVAALRW
260 270 280 290 300
VQQNIAHFGG NPDRVTIFGE SAGGTSVSSL VVSPISQGLF HGAIMESGVA
310 320 330 340 350
LLPGLIASSA DVISTVVANL SACDQVDSEA LVGCLRGKSK EEILAINKPF
360 370 380 390 400
KMIPGVVDGV FLPRHPQELL ASADFQPVPS IVGVNNNEFG WLIPKVMRIY
410 420 430 440 450
DTQKEMDREA SQAALQKMLT LLMLPPTFGD LLREEYIGDN GDPQTLQAQF
460 470 480 490 500
QEMMADSMFV IPALQVAHFQ CSRAPVYFYE FQHQPSWLKN IRPPHMKADH
510 520 530 540 550
VKFTEEEEQL SRKMMKYWAN FARNGNPNGE GLPHWPLFDQ EEQYLQLNLQ
560 570 580
PAVGRALKAH RLQFWKKALP QKIQELEEPE ERHTEL
Length:586
Mass (Da):64,823
Last modified:July 5, 2004 - v1
Checksum:i8337AE7C498633DA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC071874 mRNA. Translation: AAH71874.1.
UniGeneiHs.282975.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ6IPK9_HUMAN
AccessioniPrimary (citable) accession number: Q6IPK9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 5, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.