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Protein
Submitted name:

MGC80376 protein

Gene

ikbkb

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • identical protein binding Source: IntAct
  • IkappaB kinase activity Source: InterPro

Names & Taxonomyi

Protein namesi
Submitted name:
MGC80376 proteinImported
Gene namesi
Name:ikbkbImported
Synonyms:MGC80376Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-949882. ikbkb.

Subcellular locationi

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
itself2EBI-15915891,EBI-15915891

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

DIPiDIP-59194N.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3QA8X-ray3.60A/B/C/D/E/F/G/H1-659[»]
3RZFX-ray4.00A1-659[»]
ProteinModelPortaliQ6INT1.
SMRiQ6INT1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 291Protein kinaseInterPro annotationAdd BLAST291
Domaini291 – 357Ubiquitin-likeInterPro annotationAdd BLAST67

Phylogenomic databases

HOVERGENiHBG018241.

Family and domain databases

InterProiView protein in InterPro
IPR022007. IKKbetaNEMObind.
IPR011009. Kinase-like_dom_sf.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR029071. Ubiquitin-like_domsf.
IPR000626. Ubiquitin_dom.
PfamiView protein in Pfam
PF12179. IKKbetaNEMObind. 1 hit.
PF00069. Pkinase. 1 hit.
SMARTiView protein in SMART
SM01239. IKKbetaNEMObind. 1 hit.
SM00220. S_TKc. 1 hit.
SUPFAMiSSF54236. SSF54236. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6INT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKERLGTGGF GYVLRWIHQD TGEQVAIKQC RQELSPKNRE RWCLEIQIMK
60 70 80 90 100
KLNHPNVVSA REVPDGLQKL APNDLPLLAM EYCEGGDLRK YLNQFENCCG
110 120 130 140 150
LKEGPIRTLL SDISSALRYL HENRIIHRDL KPENIVLQPG PQRLIHKIID
160 170 180 190 200
LGYAKELDQG SLCTSFVGTL QYLAPELLEQ KKYTVTVDYW SFGTLAFECI
210 220 230 240 250
TGFRPFLPNW QPVQWHGKVR EKSNEHIVVY DDLTGAVKFS SVLPTPNHLS
260 270 280 290 300
GILAGKLERW LQCMLMWHQR QRGTDPQNPN VGCFQALDSI LSLKLLSVMN
310 320 330 340 350
MVSGRVHTYP VTENENLQNL KSWLQQDTGI PEEEQELLQA SGLALNSAQP
360 370 380 390 400
LTQYVIDCTV IDGRQGEGDL IFLFDNRKTV YEPQISLPAH PESVSIVLQD
410 420 430 440 450
PKRPLTYTHL RRVWGQIWQT IRALKEDCAR LLQGQRTSMV NLLRYNTELS
460 470 480 490 500
KKKNSMTSEC EQLKAKLDFF RSSIQIDLEK YSEQMEFGIT SEKLLSAWRE
510 520 530 540 550
MEQAVELCGR EREVQALVDK MMALQTDSVD LQRNPLGRKH RGTLDDLEEQ
560 570 580 590 600
ARDLYRRLRE RPRDQRTPGD SNDMVRLLIL AIQSFEKRVI LIYDQLSKTV
610 620 630 640 650
VCKRKALELS PKVKEVMNLM REDEKIVVRR QEKRQQELWN LLKIACSKVR
660 670 680 690 700
GPVSGSPDSL GTSRMPGPSQ LLSQPPVLSV SLAQEYVKKS EDLRSESLNL
710 720 730 740
CSQLESSMRS FMKEQDGSLM SLDWSWLLQQ EEESGASPIT TS
Length:742
Mass (Da):85,135
Last modified:July 5, 2004 - v1
Checksum:i49CBF36951AAFB0A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC072192 mRNA. Translation: AAH72192.1.
RefSeqiNP_001085125.1. NM_001091656.1.
UniGeneiXl.24009.

Genome annotation databases

GeneIDi432200.

Similar proteinsi

Entry informationi

Entry nameiQ6INT1_XENLA
AccessioniPrimary (citable) accession number: Q6INT1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 22, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources