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Protein
Submitted name:

MGC82568 protein

Gene

tgm2

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

Note: Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei277 – 2771UniRule annotation
Active sitei335 – 3351UniRule annotation
Active sitei358 – 3581UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
MGC82568 proteinImported
Gene namesi
Name:tgm2Imported
Synonyms:MGC82568Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-982477. tgm2.

Structurei

3D structure databases

ProteinModelPortaliQ6INH7.
SMRiQ6INH7. Positions 17-688.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG004342.
KOiK05625.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6INH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEELFLESF DLDCSGNNRS HRTAEASCER LIVRRGQPFQ ITLNFAPRGY
60 70 80 90 100
EEGVDRLSLN AITGPCPSEE SGTSNNFPVS DALQDGAWSA AINSTDGGTV
110 120 130 140 150
ILSITSPPNA RIGYYNLSLE TSTEYQGSSF QLGSFTLLFN PWCPEDSVYL
160 170 180 190 200
EKKDERKEYV LCQHGIIFQG TKNSTDHVPW NFGQFEDGIL EIALQILDTS
210 220 230 240 250
PKFLNDSNRD CSRRNDPVYI SRVISAMVNC NDDKGVLYGR WDNKYDDGVS
260 270 280 290 300
PMFWMGSVAI LRRWKKFGCQ AVKYGQCWVF AAVACTVLRC LGIPARVITN
310 320 330 340 350
YNSAHDTNSN LLIEQYLDEH GKRQSKQKDL IWNYHCWVEV WMARPDLGED
360 370 380 390 400
YNGWQVVDPT PQEKSEGTYC CGPAPVNAVK EGDLNVKYDV PFVFAEVNAD
410 420 430 440 450
VMYYVQQNDG SVKKTHSISL VGQNISTKAI GKDEREDITH NYKYPEGSQD
460 470 480 490 500
ERRVFEKANK QFVEAEEEEE KPLDVTIKIK VSEGMNIGSD FDVFAVITNN
510 520 530 540 550
TEDEKKCRLM FCARTTSYNG EVGPECGMKD LLNLTLPPQE EKRVPLHIQY
560 570 580 590 600
EKYGPTITEN NMIKLVAMLY DYSSKDIILA MRDIHIKNPS IKIKILGEPK
610 620 630 640 650
QKRKLVAEIS LKNPLAEPLT GCCFTVEGAG LTAEQLVQTL DCPIEPGQEA
660 670 680 690
KVRVDLMPQL PGKLSLVVDF ESDLLKAVKG YRNIIIAPLP K
Length:691
Mass (Da):77,728
Last modified:July 5, 2004 - v1
Checksum:i3C11DA1D157B031A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC072304 mRNA. Translation: AAH72304.1.
RefSeqiNP_001085410.1. NM_001091941.1.
UniGeneiXl.2480.

Genome annotation databases

GeneIDi443836.
KEGGixla:443836.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC072304 mRNA. Translation: AAH72304.1.
RefSeqiNP_001085410.1. NM_001091941.1.
UniGeneiXl.2480.

3D structure databases

ProteinModelPortaliQ6INH7.
SMRiQ6INH7. Positions 17-688.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi443836.
KEGGixla:443836.

Organism-specific databases

XenbaseiXB-GENE-982477. tgm2.

Phylogenomic databases

HOVERGENiHBG004342.
KOiK05625.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: SpleenImported.

Entry informationi

Entry nameiQ6INH7_XENLA
AccessioniPrimary (citable) accession number: Q6INH7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 26, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.