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Q6ING9 (PPM1K_XENLA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein phosphatase 1K, mitochondrial

EC=3.1.3.16
Alternative name(s):
Protein phosphatase 2C isoform kappa
Short name=PP2C-kappa
Gene names
Name:ppm1k
OrganismXenopus laevis (African clawed frog)
Taxonomic identifier8355 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Protein attributes

Sequence length373 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity.

Subcellular location

Mitochondrion matrix By similarity.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Ontologies

Keywords
   Cellular componentMitochondrion
   DomainTransit peptide
   LigandMagnesium
Manganese
Metal-binding
   Molecular functionHydrolase
Protein phosphatase
Gene Ontology (GO)
   Biological_processprotein dephosphorylation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentmitochondrial matrix

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

protein serine/threonine phosphatase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – ?Mitochondrion By similarity
Chain? – 373Protein phosphatase 1K, mitochondrialPRO_0000278211

Regions

Domain94 – 347254PP2C-like

Sites

Metal binding1281Magnesium By similarity
Metal binding1291Magnesium; via carbonyl oxygen By similarity
Metal binding3381Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6ING9 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 58713D1A52099BB7

FASTA37341,536
        10         20         30         40         50         60 
MSTAILVSLL RNGRCQVNRG ALTLCFQKEH SCTTSTRHCF SANRRCFSSR FDLDGSGRPA 

        70         80         90        100        110        120 
TWDSFGIWDN RIDEPIQLPP SIKYGKLIPH INLSKVGCST QLGKRKENED RFKLARLTPD 

       130        140        150        160        170        180 
ILYFAVYDGH GGASAAEFCD RFMEDYIKEF LVEEHDMEKV LVKAFLEINK AFARHAHLSV 

       190        200        210        220        230        240 
DASLLTCGTT ATVALLRDGI ELVVASVGDS RALLCRRGKP FKLTIDHTPE RKEEKLRIKK 

       250        260        270        280        290        300 
SGGFVTWNSL GQPNVNGRLA MTRSIGDLDL KSMGVIAEPE TKRVKLQHTD DGFLVLTTDG 

       310        320        330        340        350        360 
INFIVNSQEI CDIINQCHDP KEAAQVLTEQ AIQYGTEDNS TAIVVPFGAW GKHKSSEVSF 

       370 
SFSRGFASSG RWD 

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Ovary.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC072312 mRNA. Translation: AAH72312.1.
RefSeqNP_001085111.1. NM_001091642.1.
UniGeneXl.17302.

3D structure databases

ProteinModelPortalQ6ING9.
SMRQ6ING9. Positions 91-350.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID432182.
KEGGxla:432182.

Organism-specific databases

CTD152926.
XenbaseXB-GENE-956548. ppm1k.

Phylogenomic databases

HOVERGENHBG096199.
KOK17505.

Family and domain databases

Gene3D3.60.40.10. 1 hit.
InterProIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 1 hit.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 1 hit.
PROSITEPS01032. PP2C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePPM1K_XENLA
AccessionPrimary (citable) accession number: Q6ING9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: July 5, 2004
Last modified: February 19, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families