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Q6ING9

- PPM1K_XENLA

UniProt

Q6ING9 - PPM1K_XENLA

Protein

Protein phosphatase 1K, mitochondrial

Gene

ppm1k

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi128 – 1281MagnesiumBy similarity
    Metal bindingi129 – 1291Magnesium; via carbonyl oxygenBy similarity
    Metal bindingi338 – 3381MagnesiumBy similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: InterPro

    GO - Biological processi

    1. protein dephosphorylation Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein phosphatase 1K, mitochondrial (EC:3.1.3.16)
    Alternative name(s):
    Protein phosphatase 2C isoform kappa
    Short name:
    PP2C-kappa
    Gene namesi
    Name:ppm1k
    OrganismiXenopus laevis (African clawed frog)
    Taxonomic identifieri8355 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

    Organism-specific databases

    XenbaseiXB-GENE-956548. ppm1k.

    Subcellular locationi

    Mitochondrion matrix By similarity

    GO - Cellular componenti

    1. mitochondrial matrix Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Mitochondrion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini? – 373Protein phosphatase 1K, mitochondrialPRO_0000278211
    Transit peptidei1 – ?MitochondrionBy similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ6ING9.
    SMRiQ6ING9. Positions 91-350.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini94 – 347254PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    HOVERGENiHBG096199.
    KOiK17505.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.
    PROSITEiPS01032. PP2C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q6ING9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSTAILVSLL RNGRCQVNRG ALTLCFQKEH SCTTSTRHCF SANRRCFSSR    50
    FDLDGSGRPA TWDSFGIWDN RIDEPIQLPP SIKYGKLIPH INLSKVGCST 100
    QLGKRKENED RFKLARLTPD ILYFAVYDGH GGASAAEFCD RFMEDYIKEF 150
    LVEEHDMEKV LVKAFLEINK AFARHAHLSV DASLLTCGTT ATVALLRDGI 200
    ELVVASVGDS RALLCRRGKP FKLTIDHTPE RKEEKLRIKK SGGFVTWNSL 250
    GQPNVNGRLA MTRSIGDLDL KSMGVIAEPE TKRVKLQHTD DGFLVLTTDG 300
    INFIVNSQEI CDIINQCHDP KEAAQVLTEQ AIQYGTEDNS TAIVVPFGAW 350
    GKHKSSEVSF SFSRGFASSG RWD 373
    Length:373
    Mass (Da):41,536
    Last modified:July 5, 2004 - v1
    Checksum:i58713D1A52099BB7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC072312 mRNA. Translation: AAH72312.1.
    RefSeqiNP_001085111.1. NM_001091642.1.
    UniGeneiXl.17302.

    Genome annotation databases

    GeneIDi432182.
    KEGGixla:432182.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC072312 mRNA. Translation: AAH72312.1 .
    RefSeqi NP_001085111.1. NM_001091642.1.
    UniGenei Xl.17302.

    3D structure databases

    ProteinModelPortali Q6ING9.
    SMRi Q6ING9. Positions 91-350.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 432182.
    KEGGi xla:432182.

    Organism-specific databases

    CTDi 152926.
    Xenbasei XB-GENE-956548. ppm1k.

    Phylogenomic databases

    HOVERGENi HBG096199.
    KOi K17505.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    PROSITEi PS01032. PP2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Xenopus Gene Collection (XGC) project
      Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Ovary.

    Entry informationi

    Entry nameiPPM1K_XENLA
    AccessioniPrimary (citable) accession number: Q6ING9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 20, 2007
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3