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Protein
Submitted name:

Fatty acid binding protein 6, ileal (Gastrotropin)

Gene

fabp6

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151Cholate 1Combined sources
Binding sitei15 – 151Cholate 2Combined sources
Binding sitei50 – 501Cholate 6Combined sources
Binding sitei50 – 501Cholate 7Combined sources
Binding sitei54 – 541Cholate 1Combined sources
Binding sitei58 – 581Cholate 5Combined sources
Binding sitei58 – 581Cholate 8Combined sources
Binding sitei64 – 641Cholate 7Combined sources
Binding sitei75 – 751Cholate 6; via amide nitrogenCombined sources
Binding sitei75 – 751Cholate 7; via amide nitrogenCombined sources
Binding sitei79 – 791Cholate 9; via amide nitrogenCombined sources
Binding sitei91 – 911Cholate 7; via carbonyl oxygenCombined sources

GO - Molecular functioni

  • bile acid binding Source: ZFIN
  • transporter activity Source: InterPro

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Lipid-bindingSAAS annotation

Enzyme and pathway databases

ReactomeiR-DRE-159418. Recycling of bile acids and salts.
R-DRE-163560. Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis.

Names & Taxonomyi

Protein namesi
Submitted name:
Fatty acid binding protein 6, ileal (Gastrotropin)Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:fabp6Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 21

Organism-specific databases

ZFINiZDB-GENE-040625-49. fabp6.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSDARG00000044566.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000065447.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3ELXX-ray1.60A2-131[»]
3ELZX-ray2.20A/B/C2-131[»]
3EM0X-ray2.20A/B2-131[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni75 – 762Cholate 4 bindingCombined sources
Regioni98 – 1025Cholate 6 bindingCombined sources
Regioni98 – 1003Cholate 7 bindingCombined sources

Sequence similaritiesi

Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.SAAS annotation

Phylogenomic databases

eggNOGiKOG4015. Eukaryota.
ENOG4111US8. LUCA.
GeneTreeiENSGT00390000012034.
HOVERGENiHBG005633.
KOiK08755.
OMAiTVKMEGG.
OrthoDBiEOG091G16BV.
PhylomeDBiQ6IMW5.
TreeFamiTF330348.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR000463. Fatty_acid-bd.
IPR031257. Gastrotropin.
IPR031259. iLBP.
[Graphical view]
PANTHERiPTHR11955. PTHR11955. 1 hit.
PTHR11955:SF69. PTHR11955:SF69. 1 hit.
PRINTSiPR00178. FATTYACIDBP.
SUPFAMiSSF50814. SSF50814. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6IMW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFNGKWETE SQEGYEPFCK LIGIPDDVIA KGRDFKLVTE IVQNGDDFTW
60 70 80 90 100
TQYYPNNHVV TNKFIVGKES DMETVGGKKF KGIVSMEGGK LTISFPKYQQ
110 120 130
TTEISGGKLV ETSTASGAQG TAVLVRTSKK V
Length:131
Mass (Da):14,406
Last modified:July 5, 2004 - v1
Checksum:iDB7591088BCF3B94
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU855895 Genomic DNA. No translation available.
BC072553 mRNA. Translation: AAH72553.1.
RefSeqiNP_001002076.1. NM_001002076.2.
UniGeneiDr.86913.

Genome annotation databases

EnsembliENSDART00000065448; ENSDARP00000065447; ENSDARG00000044566.
GeneIDi415166.
KEGGidre:415166.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU855895 Genomic DNA. No translation available.
BC072553 mRNA. Translation: AAH72553.1.
RefSeqiNP_001002076.1. NM_001002076.2.
UniGeneiDr.86913.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3ELXX-ray1.60A2-131[»]
3ELZX-ray2.20A/B/C2-131[»]
3EM0X-ray2.20A/B2-131[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000065447.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000065448; ENSDARP00000065447; ENSDARG00000044566.
GeneIDi415166.
KEGGidre:415166.

Organism-specific databases

CTDi2172.
ZFINiZDB-GENE-040625-49. fabp6.

Phylogenomic databases

eggNOGiKOG4015. Eukaryota.
ENOG4111US8. LUCA.
GeneTreeiENSGT00390000012034.
HOVERGENiHBG005633.
KOiK08755.
OMAiTVKMEGG.
OrthoDBiEOG091G16BV.
PhylomeDBiQ6IMW5.
TreeFamiTF330348.

Enzyme and pathway databases

ReactomeiR-DRE-159418. Recycling of bile acids and salts.
R-DRE-163560. Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis.

Gene expression databases

BgeeiENSDARG00000044566.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR000463. Fatty_acid-bd.
IPR031257. Gastrotropin.
IPR031259. iLBP.
[Graphical view]
PANTHERiPTHR11955. PTHR11955. 1 hit.
PTHR11955:SF69. PTHR11955:SF69. 1 hit.
PRINTSiPR00178. FATTYACIDBP.
SUPFAMiSSF50814. SSF50814. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6IMW5_DANRE
AccessioniPrimary (citable) accession number: Q6IMW5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.