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Protein
Submitted name:

Fatty acid binding protein 6, ileal (Gastrotropin)

Gene

fabp6

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei15Cholate 1Combined sources1
Binding sitei15Cholate 2Combined sources1
Binding sitei50Cholate 6Combined sources1
Binding sitei50Cholate 7Combined sources1
Binding sitei54Cholate 1Combined sources1
Binding sitei58Cholate 5Combined sources1
Binding sitei58Cholate 8Combined sources1
Binding sitei64Cholate 7Combined sources1
Binding sitei75Cholate 6; via amide nitrogenCombined sources1
Binding sitei75Cholate 7; via amide nitrogenCombined sources1
Binding sitei79Cholate 9; via amide nitrogenCombined sources1
Binding sitei91Cholate 7; via carbonyl oxygenCombined sources1

GO - Molecular functioni

  • bile acid binding Source: ZFIN
  • transporter activity Source: InterPro

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Lipid-bindingSAAS annotation

Enzyme and pathway databases

ReactomeiR-DRE-159418. Recycling of bile acids and salts.
R-DRE-163560. Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis.

Names & Taxonomyi

Protein namesi
Submitted name:
Fatty acid binding protein 6, ileal (Gastrotropin)Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:fabp6Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 21

Organism-specific databases

ZFINiZDB-GENE-040625-49. fabp6.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSDARG00000044566.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000065447.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3ELXX-ray1.60A2-131[»]
3ELZX-ray2.20A/B/C2-131[»]
3EM0X-ray2.20A/B2-131[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni75 – 76Cholate 4 bindingCombined sources2
Regioni98 – 102Cholate 6 bindingCombined sources5
Regioni98 – 100Cholate 7 bindingCombined sources3

Sequence similaritiesi

Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.SAAS annotation

Phylogenomic databases

eggNOGiKOG4015. Eukaryota.
ENOG4111US8. LUCA.
GeneTreeiENSGT00390000012034.
HOVERGENiHBG005633.
KOiK08755.
OMAiTVKMEGG.
OrthoDBiEOG091G16BV.
TreeFamiTF330348.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR000463. Fatty_acid-bd.
IPR031257. Gastrotropin.
IPR031259. iLBP.
[Graphical view]
PANTHERiPTHR11955. PTHR11955. 1 hit.
PTHR11955:SF69. PTHR11955:SF69. 1 hit.
PRINTSiPR00178. FATTYACIDBP.
SUPFAMiSSF50814. SSF50814. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6IMW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFNGKWETE SQEGYEPFCK LIGIPDDVIA KGRDFKLVTE IVQNGDDFTW
60 70 80 90 100
TQYYPNNHVV TNKFIVGKES DMETVGGKKF KGIVSMEGGK LTISFPKYQQ
110 120 130
TTEISGGKLV ETSTASGAQG TAVLVRTSKK V
Length:131
Mass (Da):14,406
Last modified:July 5, 2004 - v1
Checksum:iDB7591088BCF3B94
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU855895 Genomic DNA. No translation available.
BC072553 mRNA. Translation: AAH72553.1.
RefSeqiNP_001002076.1. NM_001002076.2.
UniGeneiDr.86913.

Genome annotation databases

EnsembliENSDART00000065448; ENSDARP00000065447; ENSDARG00000044566.
GeneIDi415166.
KEGGidre:415166.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU855895 Genomic DNA. No translation available.
BC072553 mRNA. Translation: AAH72553.1.
RefSeqiNP_001002076.1. NM_001002076.2.
UniGeneiDr.86913.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3ELXX-ray1.60A2-131[»]
3ELZX-ray2.20A/B/C2-131[»]
3EM0X-ray2.20A/B2-131[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000065447.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000065448; ENSDARP00000065447; ENSDARG00000044566.
GeneIDi415166.
KEGGidre:415166.

Organism-specific databases

CTDi2172.
ZFINiZDB-GENE-040625-49. fabp6.

Phylogenomic databases

eggNOGiKOG4015. Eukaryota.
ENOG4111US8. LUCA.
GeneTreeiENSGT00390000012034.
HOVERGENiHBG005633.
KOiK08755.
OMAiTVKMEGG.
OrthoDBiEOG091G16BV.
TreeFamiTF330348.

Enzyme and pathway databases

ReactomeiR-DRE-159418. Recycling of bile acids and salts.
R-DRE-163560. Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis.

Gene expression databases

BgeeiENSDARG00000044566.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR000463. Fatty_acid-bd.
IPR031257. Gastrotropin.
IPR031259. iLBP.
[Graphical view]
PANTHERiPTHR11955. PTHR11955. 1 hit.
PTHR11955:SF69. PTHR11955:SF69. 1 hit.
PRINTSiPR00178. FATTYACIDBP.
SUPFAMiSSF50814. SSF50814. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6IMW5_DANRE
AccessioniPrimary (citable) accession number: Q6IMW5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.