Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q6IEI0

- HXB2A_TAKRU

UniProt

Q6IEI0 - HXB2A_TAKRU

Protein

Homeobox protein Hox-B2a

Gene

hoxb2a

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi173 – 23260HomeoboxPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: InterPro

    GO - Biological processi

    1. multicellular organismal development Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Developmental protein

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Homeobox protein Hox-B2a
    Gene namesi
    Name:hoxb2a
    OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)
    Taxonomic identifieri31033 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataPercomorphariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
    ProteomesiUP000005226: Unplaced

    Subcellular locationi

    Nucleus PROSITE-ProRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 415415Homeobox protein Hox-B2aPRO_0000265977Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi31033.ENSTRUP00000025073.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6IEI0.
    SMRiQ6IEI0. Positions 173-231.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi109 – 1146Antp-type hexapeptide

    Sequence similaritiesi

    Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Homeobox

    Phylogenomic databases

    eggNOGiNOG70923.
    InParanoidiQ6IEI0.
    KOiK09302.

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    InterProiIPR001827. Homeobox_Antennapedia_CS.
    IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR020479. Homeobox_metazoa.
    IPR009057. Homeodomain-like.
    [Graphical view]
    PfamiPF00046. Homeobox. 1 hit.
    [Graphical view]
    PRINTSiPR00024. HOMEOBOX.
    SMARTiSM00389. HOX. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    PROSITEiPS00032. ANTENNAPEDIA. 1 hit.
    PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6IEI0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNFEFEREIG FINSQPSLAE CLTSFPAVLE SFQTSSIKES TVIPPPFEHT    50
    IPSLSPCAAS QPRPTARNQQ NRRNSNTNGI QTHQRAAQQP CPPGQAPATA 100
    TAAGPMAPEF PWMKEKKSSK KSSKPGSSSG GGAPILPPSS ASPSPTASGY 150
    ASASIESPTD QSQAGLDAGG AGSRRLRTAY TNTQLLELEK EFHFNKYLCR 200
    PRRVEIAALL DLTERQVKVW FQNRRMKHKR QTHHRDGSGG GNDSNEPGGF 250
    EPLEGADASS PYSSQPLEAS GTGESESEQG SSNPSSAAYA SDSGDNAQST 300
    AEEGGLLGCP DRQSLSAVSG SSATHLHPLT ATNSSDNQAP LQLNRTGPEP 350
    SFSEQRDSSI PSATAALPDL TLFATDACLS PSLQSSLDSP VDFSEEDFDL 400
    FTSTLCTIDL QHLNF 415
    Length:415
    Mass (Da):44,044
    Last modified:July 5, 2004 - v1
    Checksum:i1F0246C6ECD070EB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BK005104 Genomic DNA. Translation: DAA05216.1.
    DQ481665 Genomic DNA. Translation: ABF22418.1.
    RefSeqiXP_003964308.1. XM_003964259.1.

    Genome annotation databases

    GeneIDi101073209.
    KEGGitru:101073209.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BK005104 Genomic DNA. Translation: DAA05216.1 .
    DQ481665 Genomic DNA. Translation: ABF22418.1 .
    RefSeqi XP_003964308.1. XM_003964259.1.

    3D structure databases

    ProteinModelPortali Q6IEI0.
    SMRi Q6IEI0. Positions 173-231.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 31033.ENSTRUP00000025073.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 101073209.
    KEGGi tru:101073209.

    Organism-specific databases

    CTDi 30338.

    Phylogenomic databases

    eggNOGi NOG70923.
    InParanoidi Q6IEI0.
    KOi K09302.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    InterProi IPR001827. Homeobox_Antennapedia_CS.
    IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR020479. Homeobox_metazoa.
    IPR009057. Homeodomain-like.
    [Graphical view ]
    Pfami PF00046. Homeobox. 1 hit.
    [Graphical view ]
    PRINTSi PR00024. HOMEOBOX.
    SMARTi SM00389. HOX. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    PROSITEi PS00032. ANTENNAPEDIA. 1 hit.
    PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparative genomic analysis of vertebrate Hox3 and Hox4 genes."
      Hadrys T., Prince V.E., Hunter M., Baker R., Rinkwitz S.
      J. Exp. Zool. B Mol. Dev. Evol. 302:147-164(2004)
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Highly conserved syntenic blocks at the vertebrate Hox loci and conserved regulatory elements within and outside Hox gene clusters."
      Lee A.P., Koh E.G.L., Tay A., Brenner S., Venkatesh B.
      Proc. Natl. Acad. Sci. U.S.A. 103:6994-6999(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiHXB2A_TAKRU
    AccessioniPrimary (citable) accession number: Q6IEI0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Vertebrate homeotic Hox proteins
      Nomenclature of vertebrate homeotic Hox proteins and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3