Q6IED9 (DG2L7_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative diacylglycerol O-acyltransferase 2-like protein DGAT2L7P
EC=2.3.1.-

Alternative name(s):
Diacylglycerol O-acyltransferase 2-like 7 pseudogene

Gene names

Name:

DGAT2L7P

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	249 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Uncertain

General annotation (Comments)

Function	Probable acyltransferase uses fatty acyl-CoA as substrate By similarity.
Sequence similarities	Belongs to the diacylglycerol acyltransferase family.
Caution	Could be the product of a pseudogene.

Ontologies

Keywords
Biological process	Lipid biosynthesis Lipid metabolism
Domain	Signal
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	lipid metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	transferase activity, transferring acyl groups other than amino-acyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 17	17	Potential
	Chain	18 – 249	232	Putative diacylglycerol O-acyltransferase 2-like protein DGAT2L7P		PRO_0000341692

Sequences

	Sequence		Length	Mass (Da)
	Q6IED9 [UniParc]. Last modified July 1, 2008. Version 2. Checksum: 208A05B209816E90	FASTA	249	27,571
	10 20 30 40 50 60 MLAVLYLLVK TAKLGTSWNY LFDFHPHRVL VVGAFANFCT EPTGCSCLFP KLPPHLLMLP 70 80 90 100 110 120 CWFHLLFFQD YIMSGASALP PGLVSFVKAP LPQWWPGGCP GVGGPLQALE AKPGQLSLPI 130 140 150 160 170 180 RNQKRLVKSA LELGENELFQ QFPNPQSSWV QRTQEALRPL LSVALQLFLG RRGLPLPFRA 190 200 210 220 230 240 PIRTVVGSAI PVQQSPPPSP AQVDTLQARY VGRLTQLFEE HQARYGVPAD RHLVLTEARP TAWPRLSAG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence of human chromosome 7." Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L. , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K. Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Genomic organization of the DGAT2/MOGAT gene family in cattle (Bos taurus) and other mammals." Winter A., van Eckeveld M., Bininda-Emonds O.R.P., Habermann F.A., Fries R. Cytogenet. Genome Res. 102:42-47(2003) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC004876 Genomic DNA. No translation available. BN000168 mRNA. Translation: CAD91637.1.
IPI	IPI00397431.
RefSeq	XP_003118643.3. XM_003118595.3. XP_003119099.3. XM_003119051.3. XP_003120101.3. XM_003120053.3. XP_003960459.1. XM_003960410.1.
3D structure databases
ProteinModelPortal	Q6IED9.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q6IED9. 5 interactions.
Polymorphism databases
DMDM	193806173.
Proteomic databases
PRIDE	Q6IED9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	646409.
KEGG	hsa:646409.
Organism-specific databases
CTD	646409.
GeneCards	GC07M100852.
HGNC	HGNC:44367. DGAT2L7P.
neXtProt	NX_Q6IED9.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG291508.
HOGENOM	HOG000179738.
HOVERGEN	HBG065791.
InParanoid	Q6IED9.
OrthoDB	EOG4K3KX4.
Gene expression databases
ArrayExpress	Q6IED9.
Bgee	Q6IED9.
Genevestigator	Q6IED9.
Family and domain databases
InterPro	IPR007130. DAGAT. [Graphical view]
PANTHER	PTHR12317. PTHR12317. 1 hit.
Pfam	PF03982. DAGAT. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	118789.

Entry information

Entry name

DG2L7_HUMAN

Accession

Primary (citable) accession number: Q6IED9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	April 3, 2013
This is version 56 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.