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Protein
Submitted name:

SAT protein

Gene

SAT

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
SAT proteinImported
Submitted name:
Spermidine/spermine N1-acetyltransferase, isoform CRA_bImported
Submitted name:
cDNA, FLJ92448, Homo sapiens spermidine/spermine N1-acetyltransferase (SAT), mRNAImported
Gene namesi
Name:SATImported
ORF Names:hCG_17885Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162402389.

PTM / Processingi

Proteomic databases

MaxQBiQ6ICU9.

Expressioni

Gene expression databases

BgeeiENSG00000130066.
ExpressionAtlasiQ6ICU9. baseline and differential.

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

IntActiQ6ICU9. 16 interactors.
STRINGi9606.ENSP00000368572.

Structurei

3D structure databases

SMRiQ6ICU9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 171N-acetyltransferaseInterPro annotationAdd BLAST168

Phylogenomic databases

eggNOGiKOG3216. Eukaryota.
COG0454. LUCA.
HOVERGENiHBG063175.
KOiK00657.
OMAiFYESVGA.
OrthoDBiEOG091G0UNU.
PhylomeDBiQ6ICU9.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiView protein in InterPro
IPR016181. Acyl_CoA_acyltransferase.
IPR000182. GNAT_dom.
IPR032957. SAT1.
PANTHERiPTHR10545:SF46. PTHR10545:SF46. 1 hit.
PfamiView protein in Pfam
PF00583. Acetyltransf_1. 1 hit.
SUPFAMiSSF55729. SSF55729. 1 hit.
PROSITEiView protein in PROSITE
PS51186. GNAT. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q6ICU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKFVIRPAT AADCSDILRL IKELAKYEYM EEQVILTEKD LLEDGFGEHP
60 70 80 90 100
FYHCLVAEVP KEHWTPEGHS IVGFAMYYFT YDPWIGKLLY LEDFFVMSDY
110 120 130 140 150
RGFGIGSEIL KNLSQVAMRC RCSSMHFLVA EWNEPSINFY KRRGASDLSS
160 170
EEGWRLFKID KEYLLKMATE E
Length:171
Mass (Da):20,024
Last modified:May 10, 2005 - v1
Checksum:i6A0578B88CD72F09
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei171Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312162 mRNA. Translation: BAG35096.1.
CR450294 mRNA. Translation: CAG29290.1.
CH471074 Genomic DNA. Translation: EAW99000.1.
RefSeqiNP_002961.1. NM_002970.3.
UniGeneiHs.28491.

Genome annotation databases

GeneIDi6303.
KEGGihsa:6303.
UCSCiuc004dau.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312162 mRNA. Translation: BAG35096.1.
CR450294 mRNA. Translation: CAG29290.1.
CH471074 Genomic DNA. Translation: EAW99000.1.
RefSeqiNP_002961.1. NM_002970.3.
UniGeneiHs.28491.

3D structure databases

SMRiQ6ICU9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ6ICU9. 16 interactors.
STRINGi9606.ENSP00000368572.

Proteomic databases

MaxQBiQ6ICU9.

Protocols and materials databases

DNASUi6303.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6303.
KEGGihsa:6303.
UCSCiuc004dau.5. human.

Organism-specific databases

CTDi6303.
PharmGKBiPA162402389.

Phylogenomic databases

eggNOGiKOG3216. Eukaryota.
COG0454. LUCA.
HOVERGENiHBG063175.
KOiK00657.
OMAiFYESVGA.
OrthoDBiEOG091G0UNU.
PhylomeDBiQ6ICU9.

Miscellaneous databases

ChiTaRSiSAT1. human.
GenomeRNAii6303.

Gene expression databases

BgeeiENSG00000130066.
ExpressionAtlasiQ6ICU9. baseline and differential.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiView protein in InterPro
IPR016181. Acyl_CoA_acyltransferase.
IPR000182. GNAT_dom.
IPR032957. SAT1.
PANTHERiPTHR10545:SF46. PTHR10545:SF46. 1 hit.
PfamiView protein in Pfam
PF00583. Acetyltransf_1. 1 hit.
SUPFAMiSSF55729. SSF55729. 1 hit.
PROSITEiView protein in PROSITE
PS51186. GNAT. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6ICU9_HUMAN
AccessioniPrimary (citable) accession number: Q6ICU9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: February 15, 2017
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.