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Protein
Submitted name:

SAT protein

Gene

SAT

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
SAT proteinImported
Submitted name:
Spermidine/spermine N1-acetyltransferase, isoform CRA_bImported
Submitted name:
cDNA, FLJ92448, Homo sapiens spermidine/spermine N1-acetyltransferase (SAT), mRNAImported
Gene namesi
Name:SATImported
ORF Names:hCG_17885Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162402389.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
C19orf25Q9UFG53EBI-10178867,EBI-741214
CASP7P552103EBI-10178867,EBI-523958
CCDC148Q8NFR73EBI-10178867,EBI-2349862
CCHCR1Q8TD31-33EBI-10178867,EBI-10175300
DDX39AO001483EBI-10178867,EBI-348253
DMRT3Q9NQL93EBI-10178867,EBI-9679045
EIF3DO153713EBI-10178867,EBI-353818
FAM156BQ8NDB63EBI-10178867,EBI-749727
FAM69BQ5VUD63EBI-10178867,EBI-721274
HOXB9P174823EBI-10178867,EBI-745290
LNX1Q8TBB13EBI-10178867,EBI-739832
MTA1Q133303EBI-10178867,EBI-714236
RBM17Q96I253EBI-10178867,EBI-740272
RELQ048643EBI-10178867,EBI-307352
SNAI2O436233EBI-10178867,EBI-9876238
TCF25Q9BQ703EBI-10178867,EBI-745182

Protein-protein interaction databases

STRINGi9606.ENSP00000368572.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 171168N-acetyltransferaseInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG3216. Eukaryota.
COG0454. LUCA.
GeneTreeiENSGT00440000039972.
HOVERGENiHBG063175.
KOiK00657.
OMAiFYESVGA.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000182. GNAT_dom.
IPR032957. SAT1.
[Graphical view]
PANTHERiPTHR10545:SF36. PTHR10545:SF36. 1 hit.
PfamiPF00583. Acetyltransf_1. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
PROSITEiPS51186. GNAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6ICU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKFVIRPAT AADCSDILRL IKELAKYEYM EEQVILTEKD LLEDGFGEHP
60 70 80 90 100
FYHCLVAEVP KEHWTPEGHS IVGFAMYYFT YDPWIGKLLY LEDFFVMSDY
110 120 130 140 150
RGFGIGSEIL KNLSQVAMRC RCSSMHFLVA EWNEPSINFY KRRGASDLSS
160 170
EEGWRLFKID KEYLLKMATE E
Length:171
Mass (Da):20,024
Last modified:May 10, 2005 - v1
Checksum:i6A0578B88CD72F09
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei171 – 1711Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312162 mRNA. Translation: BAG35096.1.
CR450294 mRNA. Translation: CAG29290.1.
CH471074 Genomic DNA. Translation: EAW99000.1.
RefSeqiNP_002961.1. NM_002970.3.
UniGeneiHs.28491.

Genome annotation databases

GeneIDi6303.
KEGGihsa:6303.
UCSCiuc004dau.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312162 mRNA. Translation: BAG35096.1.
CR450294 mRNA. Translation: CAG29290.1.
CH471074 Genomic DNA. Translation: EAW99000.1.
RefSeqiNP_002961.1. NM_002970.3.
UniGeneiHs.28491.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000368572.

Protocols and materials databases

DNASUi6303.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6303.
KEGGihsa:6303.
UCSCiuc004dau.5. human.

Organism-specific databases

CTDi6303.
PharmGKBiPA162402389.

Phylogenomic databases

eggNOGiKOG3216. Eukaryota.
COG0454. LUCA.
GeneTreeiENSGT00440000039972.
HOVERGENiHBG063175.
KOiK00657.
OMAiFYESVGA.

Miscellaneous databases

ChiTaRSiSAT1. human.
GenomeRNAii6303.
NextBioi24471.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000182. GNAT_dom.
IPR032957. SAT1.
[Graphical view]
PANTHERiPTHR10545:SF36. PTHR10545:SF36. 1 hit.
PfamiPF00583. Acetyltransf_1. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
PROSITEiPS51186. GNAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
    Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Cited for: NUCLEOTIDE SEQUENCE.
  4. "NEDO functional analysis of protein and research application project."
    Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T.
    Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: ThalamusImported.

Entry informationi

Entry nameiQ6ICU9_HUMAN
AccessioniPrimary (citable) accession number: Q6ICU9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 11, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.