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Protein
Submitted name:

CCL21 protein

Gene

CCL21

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
CCL21 proteinImported
Submitted name:
Chemokine (C-C motif) ligand 21Imported
Submitted name:
Efficient Chemoattractant for LymphocytesImported
Submitted name:
cDNA, FLJ92167, Homo sapiens chemokine (C-C motif) ligand 21 (CCL21), mRNAImported
Gene namesi
Name:CCL21Imported
ORF Names:hCG_20472Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  • proteinaceous extracellular matrix Source: MGI
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35552.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500878248524 – 134Sequence analysisAdd BLAST111

Expressioni

Gene expression databases

BgeeiENSG00000137077.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000259607.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 90SCYInterPro annotationAdd BLAST63

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J3QM. Eukaryota.
ENOG410Z7F2. LUCA.
HOVERGENiHBG017871.
KOiK16062.
OMAiCKRTEQP.
OrthoDBiEOG091G14NY.

Family and domain databases

InterProiIPR030593. CCL21.
IPR001811. Chemokine_IL8-like_dom.
[Graphical view]
PANTHERiPTHR12015:SF72. PTHR12015:SF72. 1 hit.
PfamiPF00048. IL8. 1 hit.
[Graphical view]
SMARTiSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMiSSF54117. SSF54117. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q6ICR7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQSLALSLL ILVLAFGIPR TQGSDGGAQD CCLKYSQRKI PAKVVRSYRK
60 70 80 90 100
QEPSLGCSIP AILFLPRKRS QAELCADPKE LWVQQLMQHL DKTPSPQKPA
110 120 130
QGCRKDRGAS KTGKKGKGSK GCKRTERSQT PKGP
Length:134
Mass (Da):14,646
Last modified:May 10, 2005 - v1
Checksum:iFB48C2F71CB4A9D2
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei134Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF030572 Genomic DNA. Translation: AAQ13417.1.
EF064765 Genomic DNA. Translation: ABK41948.1.
AK311901 mRNA. Translation: BAG34842.1.
CR450326 mRNA. Translation: CAG29322.1.
CH471071 Genomic DNA. Translation: EAW58415.1.
RefSeqiNP_002980.1. NM_002989.3.
UniGeneiHs.57907.

Genome annotation databases

GeneIDi6366.
KEGGihsa:6366.
UCSCiuc003zvo.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF030572 Genomic DNA. Translation: AAQ13417.1.
EF064765 Genomic DNA. Translation: ABK41948.1.
AK311901 mRNA. Translation: BAG34842.1.
CR450326 mRNA. Translation: CAG29322.1.
CH471071 Genomic DNA. Translation: EAW58415.1.
RefSeqiNP_002980.1. NM_002989.3.
UniGeneiHs.57907.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000259607.

Protocols and materials databases

DNASUi6366.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6366.
KEGGihsa:6366.
UCSCiuc003zvo.5. human.

Organism-specific databases

CTDi6366.
PharmGKBiPA35552.

Phylogenomic databases

eggNOGiENOG410J3QM. Eukaryota.
ENOG410Z7F2. LUCA.
HOVERGENiHBG017871.
KOiK16062.
OMAiCKRTEQP.
OrthoDBiEOG091G14NY.

Miscellaneous databases

ChiTaRSiCCL21. human.
GenomeRNAii6366.

Gene expression databases

BgeeiENSG00000137077.

Family and domain databases

InterProiIPR030593. CCL21.
IPR001811. Chemokine_IL8-like_dom.
[Graphical view]
PANTHERiPTHR12015:SF72. PTHR12015:SF72. 1 hit.
PfamiPF00048. IL8. 1 hit.
[Graphical view]
SMARTiSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMiSSF54117. SSF54117. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6ICR7_HUMAN
AccessioniPrimary (citable) accession number: Q6ICR7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 30, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.