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Protein
Submitted name:

CCL21 protein

Gene

CCL21

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CCL21 proteinImported
Submitted name:
Chemokine (C-C motif) ligand 21Imported
Submitted name:
Efficient Chemoattractant for LymphocytesImported
Submitted name:
cDNA, FLJ92167, Homo sapiens chemokine (C-C motif) ligand 21 (CCL21), mRNAImported
Gene namesi
Name:CCL21Imported
ORF Names:hCG_20472Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  • proteinaceous extracellular matrix Source: MGI

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35552.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_501014204624 – 134Sequence analysisAdd BLAST111

Expressioni

Gene expression databases

BgeeiENSG00000137077.
ExpressionAtlasiQ6ICR7. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ6ICR7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 90SCYInterPro annotationAdd BLAST63

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J3QM. Eukaryota.
ENOG410Z7F2. LUCA.
HOVERGENiHBG017871.
KOiK16062.
OMAiCKRTEQP.
OrthoDBiEOG091G14NY.

Family and domain databases

CDDicd01119. Chemokine_CC_DCCL. 1 hit.
InterProiView protein in InterPro
IPR030593. CCL21.
IPR034133. Chemokine_CC_DCCL.
IPR001811. Chemokine_IL8-like_dom.
PANTHERiPTHR12015:SF139. PTHR12015:SF139. 1 hit.
PfamiView protein in Pfam
PF00048. IL8. 1 hit.
SMARTiView protein in SMART
SM00199. SCY. 1 hit.
SUPFAMiSSF54117. SSF54117. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q6ICR7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQSLALSLL ILVLAFGIPR TQGSDGGAQD CCLKYSQRKI PAKVVRSYRK
60 70 80 90 100
QEPSLGCSIP AILFLPRKRS QAELCADPKE LWVQQLMQHL DKTPSPQKPA
110 120 130
QGCRKDRGAS KTGKKGKGSK GCKRTERSQT PKGP
Length:134
Mass (Da):14,646
Last modified:May 10, 2005 - v1
Checksum:iFB48C2F71CB4A9D2
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei134Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF030572 Genomic DNA. Translation: AAQ13417.1.
EF064765 Genomic DNA. Translation: ABK41948.1.
AK311901 mRNA. Translation: BAG34842.1.
CR450326 mRNA. Translation: CAG29322.1.
CH471071 Genomic DNA. Translation: EAW58415.1.
RefSeqiNP_002980.1. NM_002989.3.
UniGeneiHs.57907.

Genome annotation databases

GeneIDi6366.
KEGGihsa:6366.
UCSCiuc003zvo.5. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ6ICR7_HUMAN
AccessioniPrimary (citable) accession number: Q6ICR7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: July 5, 2017
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.