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Protein

Uncharacterized protein KIAA0930

Gene

KIAA0930

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein KIAA0930
Gene namesi
Name:KIAA0930
Synonyms:C22orf9
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

HGNCiHGNC:1314. KIAA0930.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000100364.
PharmGKBiPA128394623.

Polymorphism and mutation databases

BioMutaiKIAA0930.
DMDMi74748760.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002559381 – 404Uncharacterized protein KIAA0930Add BLAST404

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei267PhosphoserineCombined sources1
Modified residuei276PhosphoserineBy similarity1
Modified residuei279PhosphoserineCombined sources1
Modified residuei290PhosphothreonineCombined sources1
Modified residuei293PhosphothreonineCombined sources1
Modified residuei304PhosphoserineCombined sources1
Modified residuei306PhosphoserineCombined sources1
Modified residuei324PhosphoserineCombined sources1
Modified residuei358PhosphoserineBy similarity1
Modified residuei362PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ6ICG6.
MaxQBiQ6ICG6.
PaxDbiQ6ICG6.
PeptideAtlasiQ6ICG6.
PRIDEiQ6ICG6.

PTM databases

iPTMnetiQ6ICG6.
PhosphoSitePlusiQ6ICG6.

Expressioni

Gene expression databases

BgeeiENSG00000100364.
CleanExiHS_C22orf9.
ExpressionAtlasiQ6ICG6. baseline and differential.
GenevisibleiQ6ICG6. HS.

Organism-specific databases

HPAiHPA038091.

Interactioni

Protein-protein interaction databases

BioGridi116904. 16 interactors.
IntActiQ6ICG6. 4 interactors.
MINTiMINT-1630728.
STRINGi9606.ENSP00000251993.

Structurei

3D structure databases

ProteinModelPortaliQ6ICG6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG2465. Eukaryota.
ENOG410ZRJN. LUCA.
GeneTreeiENSGT00390000004190.
HOVERGENiHBG061712.
InParanoidiQ6ICG6.
OMAiKTNTFQG.
OrthoDBiEOG091G08PQ.
PhylomeDBiQ6ICG6.
TreeFamiTF313801.

Family and domain databases

InterProiIPR019141. DUF2045.
[Graphical view]
PfamiPF09741. DUF2045. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q6ICG6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MLRAIAEERG RLSLRREVCG LGCFKDDRIV FWTWMFSTYF MEKWAPRQDD
60 70 80 90 100
MLFYVRRKLA YSGSESGADG RKAAEPEVEV EVYRRDSKKL PGLGDPDIDW
110 120 130 140 150
EESVCLNLIL QKLDYMVTCA VCTRADGGDI HIHKKKSQQV FASPSKHPMD
160 170 180 190 200
SKGEESKISY PNIFFMIDSF EEVFSDMTVG EGEMVCVELV ASDKTNTFQG
210 220 230 240 250
VIFQGSIRYE ALKKVYDNRV SVAARMAQKM SFGFYKYSNM EFVRMKGPQG
260 270 280 290 300
KGHAEMAVSR VSTGDTSPCG TEEDSSPASP MHERVTSFST PPTPERNNRP
310 320 330 340 350
AFFSPSLKRK VPRNRIAEMK KSHSANDSEE FFREDDGGAD LHNATNLRSR
360 370 380 390 400
SLSGTGRSLV GSWLKLNRAD GNFLLYAHLT YVTLPLHRIL TDILEVRQKP

ILMT
Length:404
Mass (Da):45,794
Last modified:July 5, 2004 - v1
Checksum:i293D43C8E862E4A2
GO
Isoform 2 (identifier: Q6ICG6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-21: MLRAIAEERGRLSLRREVCGL → MGSQAAAEWRNWASWEVSSSLSGCSM

Note: No experimental confirmation available.
Show »
Length:409
Mass (Da):46,184
Checksum:i5CD3F3FCEDD00BA9
GO
Isoform 3 (identifier: Q6ICG6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-34: Missing.

Note: No experimental confirmation available.
Show »
Length:370
Mass (Da):41,728
Checksum:i6DB08AEA04178A0F
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0213101 – 34Missing in isoform 3. 1 PublicationAdd BLAST34
Alternative sequenceiVSP_0213091 – 21MLRAI…EVCGL → MGSQAAAEWRNWASWEVSSS LSGCSM in isoform 2. 1 PublicationAdd BLAST21

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR456402 mRNA. Translation: CAG30288.1.
AK094937 mRNA. Translation: BAG52960.1.
AK124648 mRNA. Translation: BAC85917.1.
AL008718 Genomic DNA. Translation: CAI17946.1.
AL008718 Genomic DNA. Translation: CAQ08665.1.
AL008718 Genomic DNA. Translation: CAQ08667.1.
CH471138 Genomic DNA. Translation: EAW73376.1.
BC016882 mRNA. Translation: AAH16882.1.
BC053595 mRNA. Translation: AAH53595.1.
AB023147 mRNA. Translation: BAA76774.1.
CCDSiCCDS33665.1. [Q6ICG6-1]
CCDS33666.1. [Q6ICG6-2]
RefSeqiNP_001009880.1. NM_001009880.1. [Q6ICG6-1]
NP_056079.1. NM_015264.1. [Q6ICG6-2]
XP_011528319.1. XM_011530017.2. [Q6ICG6-3]
UniGeneiHs.592207.

Genome annotation databases

EnsembliENST00000251993; ENSP00000251993; ENSG00000100364. [Q6ICG6-2]
ENST00000336156; ENSP00000336720; ENSG00000100364. [Q6ICG6-1]
ENST00000391627; ENSP00000375485; ENSG00000100364. [Q6ICG6-3]
GeneIDi23313.
KEGGihsa:23313.
UCSCiuc003bfw.2. human. [Q6ICG6-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR456402 mRNA. Translation: CAG30288.1.
AK094937 mRNA. Translation: BAG52960.1.
AK124648 mRNA. Translation: BAC85917.1.
AL008718 Genomic DNA. Translation: CAI17946.1.
AL008718 Genomic DNA. Translation: CAQ08665.1.
AL008718 Genomic DNA. Translation: CAQ08667.1.
CH471138 Genomic DNA. Translation: EAW73376.1.
BC016882 mRNA. Translation: AAH16882.1.
BC053595 mRNA. Translation: AAH53595.1.
AB023147 mRNA. Translation: BAA76774.1.
CCDSiCCDS33665.1. [Q6ICG6-1]
CCDS33666.1. [Q6ICG6-2]
RefSeqiNP_001009880.1. NM_001009880.1. [Q6ICG6-1]
NP_056079.1. NM_015264.1. [Q6ICG6-2]
XP_011528319.1. XM_011530017.2. [Q6ICG6-3]
UniGeneiHs.592207.

3D structure databases

ProteinModelPortaliQ6ICG6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi116904. 16 interactors.
IntActiQ6ICG6. 4 interactors.
MINTiMINT-1630728.
STRINGi9606.ENSP00000251993.

PTM databases

iPTMnetiQ6ICG6.
PhosphoSitePlusiQ6ICG6.

Polymorphism and mutation databases

BioMutaiKIAA0930.
DMDMi74748760.

Proteomic databases

EPDiQ6ICG6.
MaxQBiQ6ICG6.
PaxDbiQ6ICG6.
PeptideAtlasiQ6ICG6.
PRIDEiQ6ICG6.

Protocols and materials databases

DNASUi23313.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000251993; ENSP00000251993; ENSG00000100364. [Q6ICG6-2]
ENST00000336156; ENSP00000336720; ENSG00000100364. [Q6ICG6-1]
ENST00000391627; ENSP00000375485; ENSG00000100364. [Q6ICG6-3]
GeneIDi23313.
KEGGihsa:23313.
UCSCiuc003bfw.2. human. [Q6ICG6-1]

Organism-specific databases

CTDi23313.
GeneCardsiKIAA0930.
HGNCiHGNC:1314. KIAA0930.
HPAiHPA038091.
neXtProtiNX_Q6ICG6.
OpenTargetsiENSG00000100364.
PharmGKBiPA128394623.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2465. Eukaryota.
ENOG410ZRJN. LUCA.
GeneTreeiENSGT00390000004190.
HOVERGENiHBG061712.
InParanoidiQ6ICG6.
OMAiKTNTFQG.
OrthoDBiEOG091G08PQ.
PhylomeDBiQ6ICG6.
TreeFamiTF313801.

Miscellaneous databases

ChiTaRSiKIAA0930. human.
GeneWikiiC22orf9.
GenomeRNAii23313.
PROiQ6ICG6.

Gene expression databases

BgeeiENSG00000100364.
CleanExiHS_C22orf9.
ExpressionAtlasiQ6ICG6. baseline and differential.
GenevisibleiQ6ICG6. HS.

Family and domain databases

InterProiIPR019141. DUF2045.
[Graphical view]
PfamiPF09741. DUF2045. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiK0930_HUMAN
AccessioniPrimary (citable) accession number: Q6ICG6
Secondary accession number(s): B0QY17
, B0QY19, B3KT48, Q6ZVE5, Q7Z6K9, Q8IZ76, Q9Y2E2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: July 5, 2004
Last modified: November 30, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.