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Protein

Protein LDOC1L

Gene

LDOC1L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein LDOC1L
Alternative name(s):
Leucine zipper protein down-regulated in cancer cells-like
Mammalian retrotransposon-derived protein 6
Gene namesi
Name:LDOC1L
Synonyms:MAR6, MART6
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

HGNCiHGNC:13343. LDOC1L.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134971270.

Polymorphism and mutation databases

BioMutaiLDOC1L.
DMDMi74762303.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 239239Protein LDOC1LPRO_0000289097Add
BLAST

Proteomic databases

EPDiQ6ICC9.
MaxQBiQ6ICC9.
PaxDbiQ6ICC9.
PRIDEiQ6ICC9.

Expressioni

Gene expression databases

BgeeiQ6ICC9.
CleanExiHS_LDOC1L.
GenevisibleiQ6ICC9. HS.

Organism-specific databases

HPAiHPA005697.

Interactioni

Protein-protein interaction databases

BioGridi123975. 7 interactions.
IntActiQ6ICC9. 2 interactions.
STRINGi9606.ENSP00000340434.

Structurei

3D structure databases

ProteinModelPortaliQ6ICC9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili29 – 6941Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the LDOC1 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IVFE. Eukaryota.
ENOG4111DVS. LUCA.
GeneTreeiENSGT00510000047956.
HOGENOMiHOG000113308.
HOVERGENiHBG102708.
InParanoidiQ6ICC9.
OMAiLPTRARN.
OrthoDBiEOG7JMGF8.
PhylomeDBiQ6ICC9.
TreeFamiTF337113.

Family and domain databases

InterProiIPR032549. DUF4939.
IPR032567. LDOC1-rel.
[Graphical view]
PANTHERiPTHR15503. PTHR15503. 1 hit.
PfamiPF16297. DUF4939. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6ICC9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQPQTSKAE SPALAASPNA QMDDVIDTLT SLRLTNSALR REASTLRAEK
60 70 80 90 100
ANLTNMLESV MAELTLLRTR ARIPGALQIT PPISSITSNG TRPMTTPPTS
110 120 130 140 150
LPEPFSGDPG RLAGFLMQMD RFMIFQASRF PGEAERVAFL VSRLTGEAEK
160 170 180 190 200
WAIPHMQPDS PLRNNYQGFL AELRRTYKSP LRHARRAQIR KTSASNRAVR
210 220 230
ERQMLCRQLA SAGTGPCPVH PASNGTSPAP ALPARARNL
Length:239
Mass (Da):26,154
Last modified:July 5, 2004 - v1
Checksum:iDEF1661C6F51FBD8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR456439 mRNA. Translation: CAG30325.1.
Z75407 Genomic DNA. Translation: CAI18781.1.
BC030232 mRNA. Translation: AAH30232.1.
AK126304 mRNA. No translation available.
CCDSiCCDS33662.1.
RefSeqiNP_115663.2. NM_032287.2.
UniGeneiHs.744991.

Genome annotation databases

EnsembliENST00000341255; ENSP00000340434; ENSG00000188636.
GeneIDi84247.
KEGGihsa:84247.
UCSCiuc003beu.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR456439 mRNA. Translation: CAG30325.1.
Z75407 Genomic DNA. Translation: CAI18781.1.
BC030232 mRNA. Translation: AAH30232.1.
AK126304 mRNA. No translation available.
CCDSiCCDS33662.1.
RefSeqiNP_115663.2. NM_032287.2.
UniGeneiHs.744991.

3D structure databases

ProteinModelPortaliQ6ICC9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi123975. 7 interactions.
IntActiQ6ICC9. 2 interactions.
STRINGi9606.ENSP00000340434.

Polymorphism and mutation databases

BioMutaiLDOC1L.
DMDMi74762303.

Proteomic databases

EPDiQ6ICC9.
MaxQBiQ6ICC9.
PaxDbiQ6ICC9.
PRIDEiQ6ICC9.

Protocols and materials databases

DNASUi84247.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000341255; ENSP00000340434; ENSG00000188636.
GeneIDi84247.
KEGGihsa:84247.
UCSCiuc003beu.2. human.

Organism-specific databases

CTDi84247.
GeneCardsiLDOC1L.
H-InvDBHIX0175448.
HGNCiHGNC:13343. LDOC1L.
HPAiHPA005697.
neXtProtiNX_Q6ICC9.
PharmGKBiPA134971270.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IVFE. Eukaryota.
ENOG4111DVS. LUCA.
GeneTreeiENSGT00510000047956.
HOGENOMiHOG000113308.
HOVERGENiHBG102708.
InParanoidiQ6ICC9.
OMAiLPTRARN.
OrthoDBiEOG7JMGF8.
PhylomeDBiQ6ICC9.
TreeFamiTF337113.

Miscellaneous databases

ChiTaRSiLDOC1L. human.
GenomeRNAii84247.
NextBioi73730.
PROiQ6ICC9.

Gene expression databases

BgeeiQ6ICC9.
CleanExiHS_LDOC1L.
GenevisibleiQ6ICC9. HS.

Family and domain databases

InterProiIPR032549. DUF4939.
IPR032567. LDOC1-rel.
[Graphical view]
PANTHERiPTHR15503. PTHR15503. 1 hit.
PfamiPF16297. DUF4939. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  2. "The DNA sequence of human chromosome 22."
    Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M.
    , Buck D., Burgess J., Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y., Wright H.
    Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 87-239.
    Tissue: Trachea.

Entry informationi

Entry nameiLDOCL_HUMAN
AccessioniPrimary (citable) accession number: Q6ICC9
Secondary accession number(s): Q6ZTR1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: July 5, 2004
Last modified: March 16, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.