Q6IC07 (RFL1S_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ret finger protein-like 1 antisense gene protein

Alternative name(s):
RFPL1 antisense RNA 1
RFPL1 antisense gene protein 1

Gene names

Name:	RFPL1-AS1
Synonyms:	RFPL1S

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	111 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Tissue specificity	Strongly expressed in adult and fetal brain. Also expressed in testis. Ref.1
Miscellaneous	The gene encoding RFPL1S is located in the opposite strand of the gene encoding RFPL1. Its transcription may play a role in RFPL1 transcription regulation.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 111	111	Ret finger protein-like 1 antisense gene protein		PRO_0000341581
Experimental info
	Sequence conflict	71	1	E → EE in AJ010230. Ref.1
	Sequence conflict	81	1	R → H in AJ010230. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q6IC07 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: F3588A792064C78C	FASTA	111	11,977
	10 20 30 40 50 60 MDPPFAVNRF SADSQVPFCA CSHVHLPVVA ATGKARGAQD ANGHVKSLGK VLPILCDAPT 70 80 90 100 110 SDAPEVVRNE EVVGCVGIQG RIHCEKEKKL IRKWTEANPM PLLYFKGPNI S

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Duplications on human chromosome 22 reveal a novel Ret finger protein-like gene family with sense and endogenous antisense transcripts." Seroussi E., Kedra D., Pan H.-Q., Peyrad M., Schwartz C., Scambler P., Donnai D., Roe B.A., Dumanski J.P. Genome Res. 9:803-814(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
[2]	"A genome annotation-driven approach to cloning the human ORFeome." Collins J.E., Wright C.L., Edwards C.A., Davis M.P., Grinham J.A., Cole C.G., Goward M.E., Aguado B., Mallya M., Mokrab Y., Huckle E.J., Beare D.M., Dunham I. Genome Biol. 5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ010230 mRNA. No translation available. CR456561 mRNA. Translation: CAG30447.1.
IPI	IPI00447400.
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q6IC07.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
GeneCards	GC22M029834.
H-InvDB	HIX0041162.
HGNC	HGNC:9978. RFPL1-AS1.
MIM	605972. gene.
neXtProt	NX_Q6IC07.
GenAtlas	Search...
Gene expression databases
CleanEx	HS_RFPL1S.
Genevestigator	Q6IC07.
Family and domain databases
ProtoNet	Search...
Other
NextBio	35540196.
SOURCE	Search...

Entry information

Entry name

RFL1S_HUMAN

Accession

Primary (citable) accession number: Q6IC07

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	July 5, 2004
Last modified:	April 3, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.