Unreviewed, UniProtKB/TrEMBL Q6IBS9 (Q6IBS9_HUMAN)

Names and origin

Protein names

Submitted name:
    HADH2 protein EMBL CAG33004.1
Submitted name:
    Hydroxyacyl-Coenzyme A dehydrogenase, type II, isoform CRA_a EMBL EAW93157.1
    Hydroxysteroid (17-beta) dehydrogenase 10 EMBL CAI42653.1

Gene names

Name:	HADH2 EMBL CAG33004.1
Synonyms:	HSD17B10 EMBL CAI42653.1
ORF Names:	RP3-339A18.2-001 EMBL CAI42653.1, hCG_19788 EMBL EAW93157.1

Organism

Homo sapiens (Human) EMBL CAG33004.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	261 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family. RuleBase RU000363V1

Ontologies

Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6IBS9-1 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 9E74F242E3E6FEF1	FASTA	261	26,923
	10 20 30 40 50 60 MAAACRSVKG LVAVITGGAS GLGLATAERL VGQGASAVLL DLPNSGGEAQ AKKLGNNCVF 70 80 90 100 110 120 APADVTSEKD VQTALALAKG KFGRVDVAVN CAGIAVASKT YNLKKGQTHT LEDFQRVLDV 130 140 150 160 170 180 NLMGTFNVIR LVAGEMGQNE PDQGGQRGVI INTASVAAFE GQVGQAAYSA SKGGIVGMTL 190 200 210 220 230 240 PIARDLAPIG IRVMTIAPGL FGTPLLTSLP EKVCNFLASQ VPFPSRLGDP AEYAHLVQAI 250 260 IENPFLNGEV IRLDGAIRMQ P

References

[1]	"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)." Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Grafham D. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR456723 mRNA. Translation: CAG33004.1. Z97054 Genomic DNA. Translation: CAI42653.1. CH471154 Genomic DNA. Translation: EAW93157.1.
RefSeq	NP_004484.1.
UniGene	Hs.171280
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q6IBS9.
Genome annotation databases
Ensembl	ENSG00000072506. Homo sapiens. [Contig view]
GeneID	3028.
Organism-specific databases
HGNC	HGNC:4800. HSD17B10.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q6IBS9.
Family and domain databases
InterPro	IPR002198. DHase_sc/Rdtase_SDR. IPR002347. Glc/ribitol_DHase. IPR016040. NAD(P)-bd. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHER	PTHR19410. ADH_short_C2. 1 hit.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PRINTS	PR00081. GDHRDH. PR00080. SDRFAMILY.
PROSITE	PS00061. ADH_SHORT. 1 hit. PS00061. ADH_SHORT. 1 hit. Uncertain. [Graphical view]
Other Resources
NextBio	11984.

Entry information

Entry name

Q6IBS9_HUMAN

Accession

Primary (citable) accession number: Q6IBS9

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	December 16, 2008
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)