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Protein
Submitted name:

Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa

Gene

EIF2S2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factorImported
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Submitted name:
Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDaImported
Submitted name:
Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa, isoform CRA_bImported
Submitted name:
cDNA, FLJ93495, highly similar to Homo sapiens eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa (EIF2S2), mRNAImported
Submitted name:
eIF2S2 proteinImported
Gene namesi
Name:EIF2S2Imported
ORF Names:hCG_2018881Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000125977.6

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27696

PTM / Processingi

Proteomic databases

MaxQBiQ6IBR8
PRIDEiQ6IBR8

Expressioni

Gene expression databases

BgeeiENSG00000125977
ExpressionAtlasiQ6IBR8 baseline and differential

Structurei

3D structure databases

SMRiQ6IBR8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini199 – 308eIF2B_5InterPro annotationAdd BLAST110

Phylogenomic databases

eggNOGiKOG2768 Eukaryota
COG1601 LUCA
HOVERGENiHBG000927
KOiK03238
OMAiYAQLHAS
OrthoDBiEOG091G0H6A

Family and domain databases

InterProiView protein in InterPro
IPR002735 Transl_init_fac_IF2/IF5
IPR016189 Transl_init_fac_IF2/IF5_N
IPR016190 Transl_init_fac_IF2/IF5_Zn-bd
PfamiView protein in Pfam
PF01873 eIF-5_eIF-2B, 1 hit
SMARTiView protein in SMART
SM00653 eIF2B_5, 1 hit
SUPFAMiSSF100966 SSF100966, 1 hit
SSF75689 SSF75689, 1 hit

Sequencei

Sequence statusi: Complete.

Q6IBR8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGDEMIFDP TMSKKKKKKK KPFMLDEEGD TQTEETQPSE TKEVEPEPTE
60 70 80 90 100
DKDLEADEED TRKKDASDDL DDLNFFNQKK KKKKTKKIFD IDEAEEGVKD
110 120 130 140 150
LKIESDVQEP TEPEDDLDIM LGNKKKKKKN VKFPDEDEIL EKDEALEDED
160 170 180 190 200
NKKDDGISFS NQTGPAWAGS ERDYTYEELL NRVFNIMREK NPDMVAGEKR
210 220 230 240 250
KFVMKPPQVV RVGTKKTSFV NFTDICKLLH RQPKHLLAFL LAELGTSGSI
260 270 280 290 300
DGNNQLVIKG RFQQKQIENV LRRYIKEYVT CHTCRSPDTI LQKDTRLYFL
310 320 330
QCETCHSRCS VASIKTGFQA VTGKRAQLRA KAN
Length:333
Mass (Da):38,388
Last modified:May 10, 2005 - v1
Checksum:i3E9FD4B48AA61A51
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT009795 mRNA Translation: AAP88797.1
AK313025 mRNA Translation: BAG35860.1
CR456734 mRNA Translation: CAG33015.1
CH471077 Genomic DNA Translation: EAW76285.1
CH471077 Genomic DNA Translation: EAW76286.1
RefSeqiNP_003899.2, NM_003908.4
UniGeneiHs.429180

Genome annotation databases

GeneIDi8894
KEGGihsa:8894
UCSCiuc002xaf.4 human

Similar proteinsi

Entry informationi

Entry nameiQ6IBR8_HUMAN
AccessioniPrimary (citable) accession number: Q6IBR8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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