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Protein
Submitted name:

EIF2S2 protein

Gene

EIF2S2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Initiation factorImported

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Submitted name:
EIF2S2 proteinImported
Submitted name:
Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDaImported
Submitted name:
Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa, isoform CRA_bImported
Submitted name:
cDNA, FLJ93495, highly similar to Homo sapiens eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa (EIF2S2), mRNAImported
Gene namesi
Name:EIF2S2Imported
ORF Names:hCG_2018881Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27696.

PTM / Processingi

Proteomic databases

MaxQBiQ6IBR8.

Expressioni

Gene expression databases

BgeeiENSG00000125977.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000364119.

Structurei

3D structure databases

SMRiQ6IBR8. Positions 174-305.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini199 – 308110eIF2B_5InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG2768. Eukaryota.
COG1601. LUCA.
HOVERGENiHBG000927.
KOiK03238.
OMAiLSFKQMI.
OrthoDBiEOG091G0H6A.
PhylomeDBiQ6IBR8.

Family and domain databases

Gene3Di3.30.30.50. 1 hit.
InterProiIPR002735. Transl_init_fac_IF2/IF5.
IPR016189. Transl_init_fac_IF2/IF5_N.
IPR016190. Transl_init_fac_IF2/IF5_Zn-bd.
[Graphical view]
PfamiPF01873. eIF-5_eIF-2B. 1 hit.
[Graphical view]
SMARTiSM00653. eIF2B_5. 1 hit.
[Graphical view]
SUPFAMiSSF100966. SSF100966. 1 hit.
SSF75689. SSF75689. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6IBR8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGDEMIFDP TMSKKKKKKK KPFMLDEEGD TQTEETQPSE TKEVEPEPTE
60 70 80 90 100
DKDLEADEED TRKKDASDDL DDLNFFNQKK KKKKTKKIFD IDEAEEGVKD
110 120 130 140 150
LKIESDVQEP TEPEDDLDIM LGNKKKKKKN VKFPDEDEIL EKDEALEDED
160 170 180 190 200
NKKDDGISFS NQTGPAWAGS ERDYTYEELL NRVFNIMREK NPDMVAGEKR
210 220 230 240 250
KFVMKPPQVV RVGTKKTSFV NFTDICKLLH RQPKHLLAFL LAELGTSGSI
260 270 280 290 300
DGNNQLVIKG RFQQKQIENV LRRYIKEYVT CHTCRSPDTI LQKDTRLYFL
310 320 330
QCETCHSRCS VASIKTGFQA VTGKRAQLRA KAN
Length:333
Mass (Da):38,388
Last modified:May 10, 2005 - v1
Checksum:i3E9FD4B48AA61A51
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT009795 mRNA. Translation: AAP88797.1.
AK313025 mRNA. Translation: BAG35860.1.
CR456734 mRNA. Translation: CAG33015.1.
CH471077 Genomic DNA. Translation: EAW76285.1.
CH471077 Genomic DNA. Translation: EAW76286.1.
RefSeqiNP_003899.2. NM_003908.4.
UniGeneiHs.429180.

Genome annotation databases

GeneIDi8894.
KEGGihsa:8894.
UCSCiuc002xaf.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT009795 mRNA. Translation: AAP88797.1.
AK313025 mRNA. Translation: BAG35860.1.
CR456734 mRNA. Translation: CAG33015.1.
CH471077 Genomic DNA. Translation: EAW76285.1.
CH471077 Genomic DNA. Translation: EAW76286.1.
RefSeqiNP_003899.2. NM_003908.4.
UniGeneiHs.429180.

3D structure databases

SMRiQ6IBR8. Positions 174-305.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000364119.

Proteomic databases

MaxQBiQ6IBR8.

Protocols and materials databases

DNASUi8894.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8894.
KEGGihsa:8894.
UCSCiuc002xaf.4. human.

Organism-specific databases

CTDi8894.
PharmGKBiPA27696.

Phylogenomic databases

eggNOGiKOG2768. Eukaryota.
COG1601. LUCA.
HOVERGENiHBG000927.
KOiK03238.
OMAiLSFKQMI.
OrthoDBiEOG091G0H6A.
PhylomeDBiQ6IBR8.

Miscellaneous databases

ChiTaRSiEIF2S2. human.
GenomeRNAii8894.

Gene expression databases

BgeeiENSG00000125977.

Family and domain databases

Gene3Di3.30.30.50. 1 hit.
InterProiIPR002735. Transl_init_fac_IF2/IF5.
IPR016189. Transl_init_fac_IF2/IF5_N.
IPR016190. Transl_init_fac_IF2/IF5_Zn-bd.
[Graphical view]
PfamiPF01873. eIF-5_eIF-2B. 1 hit.
[Graphical view]
SMARTiSM00653. eIF2B_5. 1 hit.
[Graphical view]
SUPFAMiSSF100966. SSF100966. 1 hit.
SSF75689. SSF75689. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6IBR8_HUMAN
AccessioniPrimary (citable) accession number: Q6IBR8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 7, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.