Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

SIAT4C protein

Gene

SIAT4C

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseSAAS annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
SIAT4C proteinImported
Submitted name:
ST3 beta-galactoside alpha-2,3-sialyltransferase 4, isoform CRA_cImported
Submitted name:
cDNA, FLJ95600, Homo sapiens sialyltransferase 4C (beta-galactosidealpha-2,3-sialyltransferase) (SIAT4C), mRNAImported
Gene namesi
Name:SIAT4CImported
Synonyms:ST3GAL4Imported
ORF Names:hCG_37591Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatusSAAS annotation, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35766.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_500878247827 – 329Sequence analysisAdd BLAST303

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi116 ↔ 269UniRule annotation

Expressioni

Gene expression databases

BgeeiENSG00000110080.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000227495.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 29 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG2692. Eukaryota.
ENOG410XT8P. LUCA.
HOGENOMiHOG000000682.
HOVERGENiHBG056676.

Family and domain databases

InterProiIPR001675. Glyco_trans_29.
IPR012163. Sialyl_trans.
[Graphical view]
PfamiPF00777. Glyco_transf_29. 1 hit.
[Graphical view]
PIRSFiPIRSF005557. Sialyl_trans. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6IBE6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSKSRWKLL AMLALVLVVM VWYSISREDS FYFPIPEKKE PCLQGEAESK
60 70 80 90 100
ASKLFGNYSR DQPIFLRLED YFWVKTPSAY ELPYGTKGSE DLLLRVLAIT
110 120 130 140 150
SSSIPKNIQS LRCRRCVVVG NGHRLRNSSL GDAINKYDVV IRLNNAPVAG
160 170 180 190 200
YEGDVGSKTT MRLFYPESAH FDPKVENNPD TLLVLVAFKA MDFHWIETIL
210 220 230 240 250
SDKKRVRKGF WKQPPLIWDV NPKQIRILNP FFMEIAADKL LSLPMQQPRK
260 270 280 290 300
IKQKPTTGLL AITLALHLCD LVHIAGFGYP DAYNKKQTIH YYEQITLKSM
310 320
AGSGHNVSQE ALAIKRMLEM GAIKNLTSF
Length:329
Mass (Da):37,458
Last modified:May 10, 2005 - v1
Checksum:i3A1C52816B5BE9E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK314738 mRNA. Translation: BAG37279.1.
CR456858 mRNA. Translation: CAG33139.1.
CH471065 Genomic DNA. Translation: EAW67695.1.
CH471065 Genomic DNA. Translation: EAW67697.1.
RefSeqiNP_006269.1. NM_006278.2.
XP_016873623.1. XM_017018134.1.
UniGeneiHs.591947.

Genome annotation databases

GeneIDi6484.
UCSCiuc001qdu.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK314738 mRNA. Translation: BAG37279.1.
CR456858 mRNA. Translation: CAG33139.1.
CH471065 Genomic DNA. Translation: EAW67695.1.
CH471065 Genomic DNA. Translation: EAW67697.1.
RefSeqiNP_006269.1. NM_006278.2.
XP_016873623.1. XM_017018134.1.
UniGeneiHs.591947.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000227495.

Protocols and materials databases

DNASUi6484.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6484.
UCSCiuc001qdu.4. human.

Organism-specific databases

CTDi6484.
PharmGKBiPA35766.

Phylogenomic databases

eggNOGiKOG2692. Eukaryota.
ENOG410XT8P. LUCA.
HOGENOMiHOG000000682.
HOVERGENiHBG056676.

Miscellaneous databases

ChiTaRSiST3GAL4. human.
GenomeRNAii6484.

Gene expression databases

BgeeiENSG00000110080.

Family and domain databases

InterProiIPR001675. Glyco_trans_29.
IPR012163. Sialyl_trans.
[Graphical view]
PfamiPF00777. Glyco_transf_29. 1 hit.
[Graphical view]
PIRSFiPIRSF005557. Sialyl_trans. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6IBE6_HUMAN
AccessioniPrimary (citable) accession number: Q6IBE6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 30, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.