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Protein

C-C motif chemokine

Gene

CCL19

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation
Biological processChemotaxisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
C-C motif chemokineUniRule annotation
Gene namesi
Name:CCL19Imported
ORF Names:hCG_20476Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000172724.11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedUniRule annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35550

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21UniRule annotationAdd BLAST21
ChainiPRO_501420594522 – 98C-C motif chemokineUniRule annotationAdd BLAST77

Expressioni

Gene expression databases

BgeeiENSG00000172724
ExpressionAtlasiQ6IBD6 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ6IBD6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 86SCYInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the intercrine beta (chemokine CC) family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410J4UG Eukaryota
ENOG410ZG6G LUCA
HOVERGENiHBG017871
KOiK05512

Family and domain databases

CDDicd01119 Chemokine_CC_DCCL, 1 hit
InterProiView protein in InterPro
IPR000827 Chemokine_CC_CS
IPR034133 Chemokine_CC_DCCL
IPR001811 Chemokine_IL8-like_dom
IPR036048 Interleukin_8-like_sf
PfamiView protein in Pfam
PF00048 IL8, 1 hit
SMARTiView protein in SMART
SM00199 SCY, 1 hit
SUPFAMiSSF54117 SSF54117, 1 hit
PROSITEiView protein in PROSITE
PS00472 SMALL_CYTOKINES_CC, 1 hit

Sequencei

Sequence statusi: Complete.

Q6IBD6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLLALSLL VLWTSPAPTL SGTNDAEDCC LSVTQKPIPG YIVRNFHYLL
60 70 80 90
IKDGCRVPAV VFTTLRGRQL CAPPDQPWVE RIIQRLQRTS AKMKRRSS
Length:98
Mass (Da):10,993
Last modified:May 10, 2005 - v1
Checksum:i0D2516DB2EB1C81B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF064766 Genomic DNA Translation: ABK41949.1
AK311945 mRNA Translation: BAG34886.1
CR456868 mRNA Translation: CAG33149.1
CH471071 Genomic DNA Translation: EAW58416.1
RefSeqiNP_006265.1, NM_006274.2
UniGeneiHs.50002

Genome annotation databases

GeneIDi6363
KEGGihsa:6363

Similar proteinsi

Entry informationi

Entry nameiQ6IBD6_HUMAN
AccessioniPrimary (citable) accession number: Q6IBD6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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