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Protein
Submitted name:

PC4 protein

Gene

PC4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • activating transcription factor binding Source: CAFA
  • DNA helicase activity Source: CAFA
  • double-stranded DNA binding Source: CAFA
  • identical protein binding Source: CAFA
  • single-stranded DNA binding Source: CAFA
  • transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding Source: Ensembl
  • transcription coactivator activity Source: InterPro

GO - Biological processi

  • DNA duplex unwinding Source: CAFA
  • protein homooligomerization Source: CAFA
  • SMAD protein signal transduction Source: Ensembl

Names & Taxonomyi

Protein namesi
Submitted name:
PC4 proteinImported
Submitted name:
SUB1 homolog (S. cerevisiae)Imported
Submitted name:
SUB1 homolog (S. cerevisiae), isoform CRA_aImported
Submitted name:
cDNA, FLJ92014, highly similar to Homo sapiens SUB1 homolog (S. cerevisiae) (SUB1), mRNAImported
Gene namesi
Name:PC4Imported
Synonyms:SUB1Imported
ORF Names:hCG_1781938Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000113387.11.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142670858.

PTM / Processingi

Proteomic databases

MaxQBiQ6IBA2.

Expressioni

Gene expression databases

BgeeiENSG00000113387.

Interactioni

GO - Molecular functioni

  • activating transcription factor binding Source: CAFA
  • identical protein binding Source: CAFA

Structurei

3D structure databases

DisProtiDP01053.
SMRiQ6IBA2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini64 – 115PC4InterPro annotationAdd BLAST52

Phylogenomic databases

eggNOGiKOG2712. Eukaryota.
ENOG410XUB8. LUCA.
HOVERGENiHBG028243.
OMAiMVDIREH.
OrthoDBiEOG091G14VO.

Family and domain databases

Gene3Di2.30.31.10. 1 hit.
InterProiView protein in InterPro
IPR003173. PC4.
IPR009044. ssDNA-bd_transcriptional_reg.
PfamiView protein in Pfam
PF02229. PC4. 1 hit.
SUPFAMiSSF54447. SSF54447. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6IBA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKSKELVSS SSSGSDSDSE VDKKLKRKKQ VAPEKPVKKQ KTGETSRALS
60 70 80 90 100
SSKQSSSSRD DNMFQIGKMR YVSVRDFKGK VLIDIREYWM DPEGEMKPGR
110 120
KGISLNPEQW SQLKEQISDI DDAVRKL
Length:127
Mass (Da):14,395
Last modified:May 10, 2005 - v1
Checksum:i0DAE0CAAAD5E4E15
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC105972 mRNA. Translation: AAI05973.1.
AK311754 mRNA. Translation: BAG34697.1.
CR456902 mRNA. Translation: CAG33183.1.
CH471118 Genomic DNA. Translation: EAX10793.1.
CH471118 Genomic DNA. Translation: EAX10794.1.
CH471118 Genomic DNA. Translation: EAX10795.1.
CH471118 Genomic DNA. Translation: EAX10796.1.
RefSeqiNP_006704.3. NM_006713.3.
XP_011512246.1. XM_011513944.2.
XP_016864475.1. XM_017008986.1.
XP_016864476.1. XM_017008987.1.
UniGeneiHs.229641.

Genome annotation databases

GeneIDi10923.
KEGGihsa:10923.
UCSCiuc003jhs.2. human.

Similar proteinsi

Entry informationi

Entry nameiQ6IBA2_HUMAN
AccessioniPrimary (citable) accession number: Q6IBA2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 22, 2017
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.