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Protein
Submitted name:

BHLHB2 protein

Gene

BHLHB2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
BHLHB2 proteinImported
Submitted name:
Basic helix-loop-helix domain containing, class B, 2, isoform CRA_aImported
Submitted name:
Basic helix-loop-helix domain-containingImported
Submitted name:
cDNA, FLJ92873, Homo sapiens basic helix-loop-helix domain containing, class B, 2(BHLHB2), mRNAImported
Gene namesi
Name:BHLHB2Imported
ORF Names:hCG_20358Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000134107.4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25347

PTM / Processingi

Proteomic databases

MaxQBiQ6IB83

Expressioni

Gene expression databases

BgeeiENSG00000134107
ExpressionAtlasiQ6IB83 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ6IB83
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini52 – 107BHLHInterPro annotationAdd BLAST56
Domaini142 – 175OrangeInterPro annotationAdd BLAST34

Phylogenomic databases

eggNOGiKOG4304 Eukaryota
ENOG4111F0X LUCA
HOVERGENiHBG050685
KOiK03729
OMAiAGQEMFC
OrthoDBiEOG091G0D3I

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
IPR003650 Orange_dom
PfamiView protein in Pfam
PF07527 Hairy_orange, 1 hit
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SM00511 ORANGE, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit
PS51054 ORANGE, 1 hit

Sequencei

Sequence statusi: Complete.

Q6IB83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERIPSAQPP PACLPKAPGL EHGDLPGMYP AHMYQVYKSR RGIKRSEDSK
60 70 80 90 100
ETYKLPHRLI EKKRRDRINE CIAQLKDLLP EHLKLTTLGH LEKAVVLELT
110 120 130 140 150
LKHVKALTNL IDQQQQKIIA LQSGLQAGEL SGRNVETGQE MFCSGFQTCA
160 170 180 190 200
REVLQYLAKH ENTRDLKSSQ LVTHLHRVVS ELLQGGTSRK PSDPAPKVMD
210 220 230 240 250
FKEKPSSPAK GSEGPGKNCV PVIQRTFAHS SGEQSGSDTD TDSGYGGESE
260 270 280 290 300
KGDLRSEQPC FKSDHGRRFT MGERIGAIKQ ESEEPPTKKN RMQLSDDEGH
310 320 330 340 350
FTSSDLISSP FLGPHPHQPP FCLPFYLIPP SATAYLPMLE KCWYPTSVPV
360 370 380 390 400
LYPGLNASAA ALSSFMNPDK ISAPLLMPQR LPSPLPAHPS VDSSVLLQAL
410
KPIPPLNLET KD
Length:412
Mass (Da):45,510
Last modified:May 10, 2005 - v1
Checksum:i2D73A3D4980793E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF015895 Genomic DNA Translation: ABM64206.1
AK312509 mRNA Translation: BAG35410.1
CR456921 mRNA Translation: CAG33202.1
CH471055 Genomic DNA Translation: EAW63916.1
CH471055 Genomic DNA Translation: EAW63917.1
RefSeqiNP_003661.1, NM_003670.2
UniGeneiHs.744856

Genome annotation databases

GeneIDi8553
KEGGihsa:8553
UCSCiuc003bqf.4 human

Similar proteinsi

Entry informationi

Entry nameiQ6IB83_HUMAN
AccessioniPrimary (citable) accession number: Q6IB83
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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