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Protein

ATP synthase-coupling factor 6, mitochondrial

Gene

ATP5J

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processHydrogen ion transportUniRule annotation, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase-coupling factor 6, mitochondrialUniRule annotation
Short name:
ATPase subunit F6UniRule annotation
Gene namesi
Name:ATP5JImported
ORF Names:hCG_2007844Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000154723.12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25137

PTM / Processingi

Proteomic databases

MaxQBiQ6IB54
PRIDEiQ6IB54

Expressioni

Gene expression databases

BgeeiENSG00000154723
ExpressionAtlasiQ6IB54 baseline and differential

Structurei

3D structure databases

SMRiQ6IB54
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic ATPase subunit F6 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG4634 Eukaryota
ENOG41122G1 LUCA
HOVERGENiHBG062261
KOiK02131

Family and domain databases

InterProiView protein in InterPro
IPR008387 ATP_synth_f6_mt
IPR036204 ATP_synth_f6_sf_mt
PANTHERiPTHR12441 PTHR12441, 1 hit
PfamiView protein in Pfam
PF05511 ATP-synt_F6, 1 hit
PIRSFiPIRSF002455 ATP_synthase_coupling_factor_6, 1 hit
SUPFAMiSSF111357 SSF111357, 1 hit

Sequencei

Sequence statusi: Complete.

Q6IB54-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILQRLFRFS SVIRSAVSVH LRRNIGVTAV AFNKELDPIQ KLFVDKIREY
60 70 80 90 100
KSKRQTSGGP VDASSEYQQE LERELFKLKQ MFGNADMNTF PTFKFEDPKF

EVIEKPQA
Length:108
Mass (Da):12,588
Last modified:May 10, 2005 - v1
Checksum:iEDC1A14F01A10F17
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY544129 mRNA Translation: AAT11160.1
AK311899 mRNA Translation: BAG34840.1
CR456950 mRNA Translation: CAG33231.1
CH471079 Genomic DNA Translation: EAX09971.1
CH471079 Genomic DNA Translation: EAX09973.1
CH471079 Genomic DNA Translation: EAX09974.1
CH471079 Genomic DNA Translation: EAX09975.1
RefSeqiNP_001003696.1, NM_001003696.1
NP_001003697.1, NM_001003697.1
NP_001003703.1, NM_001003703.1
NP_001307195.1, NM_001320266.1
NP_001307196.1, NM_001320267.1
NP_001676.2, NM_001685.4
UniGeneiHs.246310

Genome annotation databases

GeneIDi522
KEGGihsa:522
UCSCiuc002yls.4 human

Similar proteinsi

Entry informationi

Entry nameiQ6IB54_HUMAN
AccessioniPrimary (citable) accession number: Q6IB54
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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