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Protein
Submitted name:

MYL2 protein

Gene

MYL2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi37 – 48PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
MYL2 proteinImported
Submitted name:
Myosin, light polypeptide 2, regulatory, cardiac, slow, isoform CRA_aImported
Submitted name:
cDNA, FLJ92288, highly similar to Homo sapiens myosin, light polypeptide 2, regulatory, cardiac, slow (MYL2), mRNAImported
Gene namesi
Name:MYL2Imported
ORF Names:hCG_40212Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000111245.14

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31380

PTM / Processingi

Proteomic databases

PRIDEiQ6IB42

Expressioni

Gene expression databases

BgeeiENSG00000111245
ExpressionAtlasiQ6IB42 baseline and differential

Structurei

3D structure databases

SMRiQ6IB42
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 59EF-handInterPro annotationAdd BLAST36
Domaini94 – 129EF-handInterPro annotationAdd BLAST36
Domaini130 – 165EF-handInterPro annotationAdd BLAST36

Phylogenomic databases

eggNOGiKOG0031 Eukaryota
COG5126 LUCA
HOVERGENiHBG012180
KOiK10351
OMAiIVTHRAE
OrthoDBiEOG091G0QF6

Family and domain databases

CDDicd00051 EFh, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
PfamiView protein in Pfam
PF13405 EF-hand_6, 1 hit
SMARTiView protein in SMART
SM00054 EFh, 3 hits
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 3 hits

Sequencei

Sequence statusi: Complete.

Q6IB42-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPKKAKKRA GGANSNVFSM FEQTQIQEFK EAFTIMDQNR DGFIDKNDLR
60 70 80 90 100
DTFAALGRVN VKNEEIDEMI KEAPGPINFT VFLTMFGEKL KGADPEETIL
110 120 130 140 150
NAFKVFDPEG KGVLKADYVR EMLTTQAERF SKEEVDQMFA AFPPDVTGNL
160
DYKNLVHIIT HGEEKD
Length:166
Mass (Da):18,789
Last modified:May 10, 2005 - v1
Checksum:iEA0BEF886AA3FAF5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei166Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312013 mRNA Translation: BAG34951.1
CR456962 mRNA Translation: CAG33243.1
CR541957 mRNA Translation: CAG46755.1
CH471054 Genomic DNA Translation: EAW97943.1
RefSeqiNP_000423.2, NM_000432.3
UniGeneiHs.75535

Genome annotation databases

GeneIDi4633
KEGGihsa:4633
UCSCiuc001try.5 human

Similar proteinsi

Entry informationi

Entry nameiQ6IB42_HUMAN
AccessioniPrimary (citable) accession number: Q6IB42
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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