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Protein
Submitted name:

MYL2 protein

Gene

MYL2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
MYL2 proteinImported
Submitted name:
Myosin, light polypeptide 2, regulatory, cardiac, slow, isoform CRA_aImported
Submitted name:
cDNA, FLJ92288, highly similar to Homo sapiens myosin, light polypeptide 2, regulatory, cardiac, slow (MYL2), mRNAImported
Gene namesi
Name:MYL2Imported
ORF Names:hCG_40212Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31380.

Expressioni

Gene expression databases

BgeeiENSG00000111245.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000228841.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 59EF-handInterPro annotationAdd BLAST36
Domaini94 – 129EF-handInterPro annotationAdd BLAST36
Domaini130 – 165EF-handInterPro annotationAdd BLAST36

Phylogenomic databases

eggNOGiKOG0031. Eukaryota.
COG5126. LUCA.
HOVERGENiHBG012180.
KOiK10351.
OMAiKDYVTEM.
OrthoDBiEOG091G0QF6.

Family and domain databases

CDDicd00051. EFh. 1 hit.
Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13405. EF-hand_6. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 3 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6IB42-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPKKAKKRA GGANSNVFSM FEQTQIQEFK EAFTIMDQNR DGFIDKNDLR
60 70 80 90 100
DTFAALGRVN VKNEEIDEMI KEAPGPINFT VFLTMFGEKL KGADPEETIL
110 120 130 140 150
NAFKVFDPEG KGVLKADYVR EMLTTQAERF SKEEVDQMFA AFPPDVTGNL
160
DYKNLVHIIT HGEEKD
Length:166
Mass (Da):18,789
Last modified:May 10, 2005 - v1
Checksum:iEA0BEF886AA3FAF5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei166Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312013 mRNA. Translation: BAG34951.1.
CR456962 mRNA. Translation: CAG33243.1.
CR541957 mRNA. Translation: CAG46755.1.
CH471054 Genomic DNA. Translation: EAW97943.1.
RefSeqiNP_000423.2. NM_000432.3.
UniGeneiHs.75535.

Genome annotation databases

GeneIDi4633.
KEGGihsa:4633.
UCSCiuc001try.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312013 mRNA. Translation: BAG34951.1.
CR456962 mRNA. Translation: CAG33243.1.
CR541957 mRNA. Translation: CAG46755.1.
CH471054 Genomic DNA. Translation: EAW97943.1.
RefSeqiNP_000423.2. NM_000432.3.
UniGeneiHs.75535.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000228841.

Protocols and materials databases

DNASUi4633.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4633.
KEGGihsa:4633.
UCSCiuc001try.5. human.

Organism-specific databases

CTDi4633.
PharmGKBiPA31380.

Phylogenomic databases

eggNOGiKOG0031. Eukaryota.
COG5126. LUCA.
HOVERGENiHBG012180.
KOiK10351.
OMAiKDYVTEM.
OrthoDBiEOG091G0QF6.

Miscellaneous databases

ChiTaRSiMYL2. human.
GenomeRNAii4633.

Gene expression databases

BgeeiENSG00000111245.

Family and domain databases

CDDicd00051. EFh. 1 hit.
Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13405. EF-hand_6. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 3 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6IB42_HUMAN
AccessioniPrimary (citable) accession number: Q6IB42
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 30, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.