Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

PGRMC1 protein

Gene

PGRMC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
PGRMC1 proteinImported
Submitted name:
Progesterone receptor membrane component 1Imported
Submitted name:
Progesterone receptor membrane component 1, isoform CRA_aImported
Submitted name:
cDNA, FLJ94602, Homo sapiens progesterone receptor membrane component 1 (PGRMC1),mRNAImported
Gene namesi
Name:PGRMC1Imported
ORF Names:hCG_23188Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000101856.9.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei25 – 43HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33248.

PTM / Processingi

Proteomic databases

MaxQBiQ6IB11.

Expressioni

Gene expression databases

BgeeiENSG00000101856.
ExpressionAtlasiQ6IB11. baseline and differential.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CREB3L1Q96BA83EBI-10249941,EBI-6942903

Protein-protein interaction databases

IntActiQ6IB11. 1 interactor.
MINTiMINT-5003213.

Structurei

3D structure databases

SMRiQ6IB11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini73 – 171Cytochrome b5 heme-bindingInterPro annotationAdd BLAST99

Sequence similaritiesi

Belongs to the cytochrome b5 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1110. Eukaryota.
ENOG4111UG0. LUCA.
HOVERGENiHBG059971.
KOiK17278.
OMAiEWETQFT.
OrthoDBiEOG091G0PXT.

Family and domain databases

Gene3Di3.10.120.10. 1 hit.
InterProiView protein in InterPro
IPR001199. Cyt_B5-like_heme/steroid-bd.
PfamiView protein in Pfam
PF00173. Cyt-b5. 1 hit.
SMARTiView protein in SMART
SM01117. Cyt-b5. 1 hit.
SUPFAMiSSF55856. SSF55856. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6IB11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAEDVVATG ADPSDLESGG LLHEIFTSPL NLLLLGLCIF LLYKIVRGDQ
60 70 80 90 100
PAASGDSDDD EPPPLPRLKR RDFTPAELRR FDGVQDPRIL MAINGKVFDV
110 120 130 140 150
TKGRKFYGPE GPYGVFAGRD ASRGLATFCL DKEALKDEYD DLSDLTAAQQ
160 170 180 190
ETLSDWESQF TFKYHHVGKL LKEGEEPTVY SDEEEPKDES ARKND
Length:195
Mass (Da):21,671
Last modified:May 10, 2005 - v1
Checksum:iCCD5E802E1C9E604
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ496104 Genomic DNA. Translation: ABF47093.1.
AK313956 mRNA. Translation: BAG36672.1.
CR456993 mRNA. Translation: CAG33274.1.
CH471161 Genomic DNA. Translation: EAW89879.1.
CH471161 Genomic DNA. Translation: EAW89882.1.
RefSeqiNP_006658.1. NM_006667.4.
UniGeneiHs.90061.

Genome annotation databases

GeneIDi10857.
KEGGihsa:10857.
UCSCiuc004erb.5. human.

Similar proteinsi

Entry informationi

Entry nameiQ6IB11_HUMAN
AccessioniPrimary (citable) accession number: Q6IB11
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 27, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.