Unreviewed, UniProtKB/TrEMBL Q6IAZ4 (Q6IAZ4_HUMAN)

Names and origin

Protein names

Submitted name:
    AKR1A1 protein EMBL CAG33291.1
Submitted name:
    Aldo-keto reductase family 1, member A1 (Aldehyde reductase) EMBL CAI22459.1
    Aldo-keto reductase family 1, member A1 (Aldehyde reductase), isoform CRA_a EMBL EAX06970.1

Gene names

Name:	AKR1A1 EMBL CAG33291.1
ORF Names:	RP4-697E16.2-001 EMBL CAI22459.1, hCG_201515 EMBL EAX06970.1

Organism

Homo sapiens (Human) EMBL CAG33291.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	325 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6IAZ4-1 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: F6B27517EB754E37	FASTA	325	36,573
	10 20 30 40 50 60 MAASCVLLHT GQKMPLIGLG TWKSEPGQVK AAVKYALSVG YRHIDCAAIY GNEPEIGEAL 70 80 90 100 110 120 KEDVGPGKAV PREELFVTSK LWNTKHHPED VEPALRKTLA DLQLEYLDLY LMHWPYAFER 130 140 150 160 170 180 GDNPFPKNAD GTICYDSTHY KETWKALEAL VAKGLVQALG LSNFNSRQID DILSVASVRP 190 200 210 220 230 240 AVLQVECHPY LAQNELIAHC QARGLEVTAY SPLGSSDRAW RDPDEPVLLE EPVVLALAEK 250 260 270 280 290 300 YGRSPAQILL RWQVQRKVIC IPKSITPSRI LQNIKVFDFT FSPEEMKQLN ALNKNWRYIV 310 320 PMLTVDGKRV PRDAGHPLYP FNDPY

References

[1]	"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)." Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Wallis J. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR457010 mRNA. Translation: CAG33291.1. AL355480 Genomic DNA. Translation: CAI22459.1. CH471059 Genomic DNA. Translation: EAX06970.1.
RefSeq	NP_006057.1. NP_697021.1.
UniGene	Hs.654435
3D structure databases
SMR	Q6IAZ4. Positions 2-325.
ModBase	Search...
Proteomic databases
PRIDE	Q6IAZ4.
Genome annotation databases
Ensembl	ENSG00000117448. Homo sapiens. [Contig view]
GeneID	10327.
KEGG	hsa:10327.
Organism-specific databases
HGNC	HGNC:380. AKR1A1.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q6IAZ4.
Gene expression databases
ArrayExpress	Q6IAZ4.
Family and domain databases
InterPro	IPR001395. Aldo/ket_red. [Graphical view]
Gene3D	G3DSA:3.20.20.100. Aldo/ket_red. 1 hit.
PANTHER	PTHR11732. Aldo/ket_red. 1 hit.
Pfam	PF00248. Aldo_ket_red. 1 hit. [Graphical view]
PRINTS	PR00069. ALDKETRDTASE.
ProDom	PD000288. Aldo/ket_red. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00798. ALDOKETO_REDUCTASE_1. 1 hit. PS00062. ALDOKETO_REDUCTASE_2. 1 hit. PS00063. ALDOKETO_REDUCTASE_3. 1 hit. [Graphical view]
Other Resources
NextBio	39151.

Entry information

Entry name

Q6IAZ4_HUMAN

Accession

Primary (citable) accession number: Q6IAZ4

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	December 16, 2008
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)