Q6IAX6 (Q6IAX6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
3'-phosphoadenosine 5'-phosphosulfate synthase 1 EMBL EAX06210.1

Submitted name:
PAPSS1 protein EMBL CAG33309.1
Submitted name:
cDNA FLJ76465, highly similar to Homo sapiens 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPSS1), mRNA EMBL BAF85463.1

Gene names

Name:	PAPSS1 EMBL CAG33309.1
ORF Names:	hCG_20920 EMBL EAX06210.1

Organism

Homo sapiens (Human) EMBL CAG33309.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	624 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	sulfate assimilation Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6IAX6 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: A3DC9B943E68CDD6	FASTA	624	70,833
	10 20 30 40 50 60 MEIPGSLCKK VKLSNNAQNW GMQRATNVTY QAHHVSRNKR GQVVGTRGGF RGCTVWLTGL 70 80 90 100 110 120 SGAGKTTVSM ALEEYLVCHG IPCYTLDGDN IRQGLNKNLG FSPEDREENV RRIAEVAKLF 130 140 150 160 170 180 ADAGLVCITS FISPYTQDRN NARQIHEGAS LPFFEVFVDA PLHVCEQRDV KGLYKKARAG 190 200 210 220 230 240 EIKGFTGIDS EYEKPEAPEL VLKTDSCDVN DCVQQVVELL QERDIVPVDA SYEVKELYVP 250 260 270 280 290 300 ENKLHLAKTD AETLPALKIN KVDMQWVQVL AEGWATPLNG FMREREYLQC LHFDCLLDGG 310 320 330 340 350 360 VINLSVPIVL TATHEDKERL DGCTAFALMY EGRRVAILRN PEFFEHRKEE RCARQWGTTC 370 380 390 400 410 420 KNHPYIKMVM EQGDWLIGGD LQVLDRVYWN DGLDQYRLTP TELKQKFKDM NADAVFAFQL 430 440 450 460 470 480 RNPVHNGHAL LMQDTHKQLL ERGYRRPVLL LHPLGGWTKD DDVPLMWRMK QHAAVLEEGV 490 500 510 520 530 540 LNPETTVVAI FPSPMMYAGP TEVQWHCRAR MVAGANFYIV GRDPAGMPHP ETGKDLYEPS 550 560 570 580 590 600 HGAKVLTMAP GLITLEIVPF RVAAYNKKKK RMDYYDSEHH EDFEFISGTR MRKLAREGQK 610 620 PPEGFMAPKA WTVLTEYYKS LEKA

References

[1]	"NEDO human cDNA sequencing project." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Trachea EMBL BAF85463.1.
[2]	"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)." Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK292774 mRNA. Translation: BAF85463.1. CR457028 mRNA. Translation: CAG33309.1. CH471057 Genomic DNA. Translation: EAX06210.1.
IPI	IPI00011619.
RefSeq	NP_005434.4. NM_005443.4.
UniGene	Hs.368610.
3D structure databases
ProteinModelPortal	Q6IAX6.
SMR	Q6IAX6. Positions 25-623.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6IAX6.
Proteomic databases
PRIDE	Q6IAX6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	9061.
KEGG	hsa:9061.
Organism-specific databases
CTD	9061.
Phylogenomic databases
GeneTree	ENSGT00390000009613.
HOVERGEN	HBG053503.
OMA	AQNWGMQ.
PhylomeDB	Q6IAX6.
Gene expression databases
ArrayExpress	Q6IAX6.
Bgee	Q6IAX6.
Family and domain databases
HAMAP	MF_00065. Adenylyl_sulf_kinase. [Tree]
InterPro	IPR002891. APS_kinase_C. IPR015947. PUA-like_domain. IPR014729. Rossmann-like_a/b/a_fold. IPR002650. Sulphate_adenylyltransferase. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KO	K13811.
Pfam	PF01583. APS_kinase. 1 hit. PF01747. ATP-sulfurylase. 1 hit. [Graphical view]
SUPFAM	SSF88697. PUA-like. 1 hit.
TIGRFAMs	TIGR00455. ApsK. 1 hit. TIGR00339. SopT. 1 hit.
ProtoNet	Search...
Other
NextBio	33955.

Entry information

Entry name

Q6IAX6_HUMAN

Accession

Primary (citable) accession number: Q6IAX6

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	November 16, 2011
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.