Q6IAX5 (Q6IAX5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Eukaryotic translation initiation factor 3 subunit E PIRNR PIRNR016255

Gene names

Name:

EIF3S6 EMBL CAG33310.1

Organism

Homo sapiens (Human) EMBL CAG33310.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	445 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subunit structure	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex By similarity. PIRNR PIRNR016255
Subcellular location	Cytoplasm By similarity PIRNR PIRNR016255.
Sequence similarities	Belongs to the eIF-3 subunit E family. PIRNR PIRNR016255 Contains 1 PCI domain. SAAS SAAS019010

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm SAAS SAAS019010 PIRNR PIRNR016255
Molecular function	Initiation factor SAAS SAAS019010 PIRNR PIRNR016255
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	translation initiation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6IAX5 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: C7C0FF755BD9A8D4	FASTA	445	52,206
	10 20 30 40 50 60 MAEYDLTTRI AHFLDRHLVF PLLEFLSVKE IYNEKELLQG KLDLLSDTNM VDFAMDVYKN 70 80 90 100 110 120 LYSDDIPHAL REKRTTVVAQ LKQLQAETEP IVKMFEDPET TRQMQSTRDG RMLFDYLADK 130 140 150 160 170 180 HGFRQEYLDT LYRYAKFQYE CGNYSGAAEY LYFFRVLVPA TDRNALSSLW GKLASEILMQ 190 200 210 220 230 240 NWDAAMEDLT RLKETIDNNS VSSPLQSLQQ RTWLIHWSLF VFFNHPKGRD NIIDLFLYQP 250 260 270 280 290 300 QYLNAIQTMC PHILRYLTTA VITNKDVRKR RLVLKDLVKV IQQESYTYKD PITEFVECLY 310 320 330 340 350 360 VNFDFDGAQK KLRECESVLV NDFFLVACLE DFIENARLFI FETFCRIHQC ISINMLADKL 370 380 390 400 410 420 NMTPEEAERW IVNLIRNARL DAKIDSKLGH VVMGNNAVSP YQQVIEKTKS LSFRSQMLAM 430 440 NIEKKLNQNS RSEAPNWATQ DSGFY

References

[1]	"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)." Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR457029 mRNA. Translation: CAG33310.1.
IPI	IPI00013068.
UniGene	Hs.405590.
3D structure databases
ProteinModelPortal	Q6IAX5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6IAX5.
Proteomic databases
PRIDE	Q6IAX5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG001097.
Gene expression databases
ArrayExpress	Q6IAX5.
Family and domain databases
Gene3D	1.10.10.10. 1 hit.
InterPro	IPR019010. eIF3_su6_N. IPR000717. PCI_dom. IPR016650. Transl_init_fac_3_su6_euk. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
Pfam	PF09440. eIF3_N. 1 hit. PF01399. PCI. 1 hit. [Graphical view]
PIRSF	PIRSF016255. eIF3e_su6. 1 hit.
SMART	SM00088. PINT. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	EIF3E. human.

Entry information

Entry name

Q6IAX5_HUMAN

Accession

Primary (citable) accession number: Q6IAX5

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.