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Protein
Submitted name:

CALU protein

Gene

CALU

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi81 – 92PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi117 – 128PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi201 – 212PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi242 – 253PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi278 – 289PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

Keywordsi

LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
CALU proteinImported
Submitted name:
CalumeninImported
Submitted name:
Calumenin, isoform CRA_bImported
Submitted name:
cDNA, FLJ92797, Homo sapiens calumenin (CALU), mRNAImported
Gene namesi
Name:CALUImported
ORF Names:hCG_41656Imported, tcag7.422Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000128595.16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26047

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_501431047620 – 315Sequence analysisAdd BLAST296

Expressioni

Gene expression databases

BgeeiENSG00000128595

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini68 – 103EF-handInterPro annotationAdd BLAST36
Domaini104 – 139EF-handInterPro annotationAdd BLAST36
Domaini151 – 186EF-handInterPro annotationAdd BLAST36
Domaini188 – 223EF-handInterPro annotationAdd BLAST36
Domaini242 – 264EF-handInterPro annotationAdd BLAST23
Domaini265 – 300EF-handInterPro annotationAdd BLAST36

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4223 Eukaryota
ENOG410XRVE LUCA
HOVERGENiHBG002834

Family and domain databases

InterProiView protein in InterPro
IPR027239 Calumenin
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
PANTHERiPTHR10827:SF70 PTHR10827:SF70, 1 hit
PfamiView protein in Pfam
PF13202 EF-hand_5, 2 hits
PF13833 EF-hand_8, 1 hit
SMARTiView protein in SMART
SM00054 EFh, 4 hits
SUPFAMiSSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 4 hits
PS50222 EF_HAND_2, 6 hits

Sequencei

Sequence statusi: Complete.

Q6IAW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLRQFLMCL SLCTAFALSK PTEKKDRVHH EPQLSDKVHN DAQSFDYDHD
60 70 80 90 100
AFLGAEEAKT FDQLTPEESK ERLGKIVSKI DGDKDGFVTV DELKDWIKFA
110 120 130 140 150
QKRWIYEDVE RQWKGHDLNE DGLVSWEEYK NATYGYVLDD PDPDDGFNYK
160 170 180 190 200
QMMVRDERRF KMADKDGDLI ATKEEFTAFL HPEEYDYMKD IVVQETMEDI
210 220 230 240 250
DKNADGFIDL EEYIGDMYSH DGNTDEPEWV KTEREQFVEF RDKNRDGKMD
260 270 280 290 300
KEETKDWILP SDYDHAEAEA RHLVYESDQN KDGKLTKEEI VDKYDLFVGS
310
QATDFGEALV RHDEF
Length:315
Mass (Da):37,107
Last modified:May 10, 2005 - v1
Checksum:i25BAE5A99B527375
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT006826 mRNA Translation: AAP35472.1
BT020143 mRNA Translation: AAV38945.1
AK312446 mRNA Translation: BAG35353.1
CR457039 mRNA Translation: CAG33320.1
CH236950 Genomic DNA Translation: EAL24113.1
CH471070 Genomic DNA Translation: EAW83677.1
CH471070 Genomic DNA Translation: EAW83678.1
RefSeqiNP_001210.1, NM_001219.4
UniGeneiHs.743262
Hs.7753

Genome annotation databases

GeneIDi813
UCSCiuc003vnq.4 human

Similar proteinsi

Entry informationi

Entry nameiQ6IAW5_HUMAN
AccessioniPrimary (citable) accession number: Q6IAW5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: April 25, 2018
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.