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Protein
Submitted name:

GABA(A) receptor-associated protein

Gene

GABARAP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywordsi

Molecular functionReceptorImported
Biological processAutophagyUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
GABA(A) receptor-associated proteinImported
Submitted name:
GABARAP proteinImported
Submitted name:
HCG1987397, isoform CRA_bImported
Gene namesi
Name:GABARAPImported
ORF Names:hCG_1987397Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28480.

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi116Phosphatidylethanolamine amidated glycineUniRule annotation1

Keywords - PTMi

LipoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiENSG00000170296.
ExpressionAtlasiQ6IAW1. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiQ6IAW1. 3 interactors.
STRINGi9606.ENSP00000306866.

Structurei

3D structure databases

SMRiQ6IAW1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATG8 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1654. Eukaryota.
ENOG4111JAT. LUCA.
HOVERGENiHBG051706.
KOiK08341.
OMAiTTMGQLY.
OrthoDBiEOG091G10QX.
PhylomeDBiQ6IAW1.

Family and domain databases

CDDicd01611. GABARAP. 1 hit.
InterProiIPR004241. Atg8-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR10969. PTHR10969. 1 hit.
PfamiPF02991. Atg8. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6IAW1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFVYKEEHP FEKRRSEGEK IRKKYPDRVP VIVEKAPKAR IGDLDKKKYL
60 70 80 90 100
VPSDLTVGQF YFLIRKRIHL RAEDALFFFV NNVIPPTSAT MGQLYQEHHE
110
EDFFLYIAYS DESVYGL
Length:117
Mass (Da):13,918
Last modified:May 10, 2005 - v1
Checksum:iBC0B84B8A51C1E32
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei117Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC106748 mRNA. Translation: AAI06749.1.
BC106749 mRNA. Translation: AAI06750.1.
CR457043 mRNA. Translation: CAG33324.1.
CR542235 mRNA. Translation: CAG47031.1.
CH471108 Genomic DNA. Translation: EAW90234.1.
CH471108 Genomic DNA. Translation: EAW90238.1.
RefSeqiNP_009209.1. NM_007278.1.
UniGeneiHs.647421.

Genome annotation databases

GeneIDi11337.
KEGGihsa:11337.
UCSCiuc002gfb.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC106748 mRNA. Translation: AAI06749.1.
BC106749 mRNA. Translation: AAI06750.1.
CR457043 mRNA. Translation: CAG33324.1.
CR542235 mRNA. Translation: CAG47031.1.
CH471108 Genomic DNA. Translation: EAW90234.1.
CH471108 Genomic DNA. Translation: EAW90238.1.
RefSeqiNP_009209.1. NM_007278.1.
UniGeneiHs.647421.

3D structure databases

SMRiQ6IAW1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ6IAW1. 3 interactors.
STRINGi9606.ENSP00000306866.

Protocols and materials databases

DNASUi11337.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11337.
KEGGihsa:11337.
UCSCiuc002gfb.4. human.

Organism-specific databases

CTDi11337.
PharmGKBiPA28480.

Phylogenomic databases

eggNOGiKOG1654. Eukaryota.
ENOG4111JAT. LUCA.
HOVERGENiHBG051706.
KOiK08341.
OMAiTTMGQLY.
OrthoDBiEOG091G10QX.
PhylomeDBiQ6IAW1.

Miscellaneous databases

ChiTaRSiGABARAP. human.
GenomeRNAii11337.

Gene expression databases

BgeeiENSG00000170296.
ExpressionAtlasiQ6IAW1. baseline and differential.

Family and domain databases

CDDicd01611. GABARAP. 1 hit.
InterProiIPR004241. Atg8-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR10969. PTHR10969. 1 hit.
PfamiPF02991. Atg8. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6IAW1_HUMAN
AccessioniPrimary (citable) accession number: Q6IAW1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: January 18, 2017
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.