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Protein
Submitted name:

PPM1G protein

Gene

PPM1G

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

Mg2+SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protein phosphataseUniRule annotationSAAS annotation
LigandMagnesiumSAAS annotation, Metal-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
PPM1G proteinImported
Submitted name:
Protein phosphatase 1G (Formerly 2C), magnesium-dependent, gamma isoformImported
Submitted name:
Putative uncharacterized protein PPM1GImported
Gene namesi
Name:PPM1GImported
ORF Names:hCG_21229Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33606.

PTM / Processingi

Proteomic databases

MaxQBiQ6IAU5.

Expressioni

Gene expression databases

BgeeiENSG00000115241.

Interactioni

Protein-protein interaction databases

IntActiQ6IAU5. 1 interactor.
MINTiMINT-4901945.
STRINGi9606.ENSP00000264714.

Structurei

3D structure databases

SMRiQ6IAU5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 505PPM-type phosphataseInterPro annotationAdd BLAST480

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili257 – 280Sequence analysisAdd BLAST24
Coiled coili284 – 311Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the PP2C family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0699. Eukaryota.
COG0631. LUCA.
HOVERGENiHBG053647.
KOiK17499.
OMAiGWRNSQE.
OrthoDBiEOG091G0D0W.

Family and domain databases

Gene3Di3.60.40.10. 2 hits.
InterProiView protein in InterPro
IPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiView protein in Pfam
PF00481. PP2C. 2 hits.
SMARTiView protein in SMART
SM00332. PP2Cc. 1 hit.
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiView protein in PROSITE
PS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6IAU5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAYLSQPNT VKCSGDGVGA PRLPLPYGFS AMQGWRVSME DAHNCIPELD
60 70 80 90 100
SETAMFSVYD GHGGEEVALY CAKYLPDIIK DQKAYKEGKL QKALEDAFLA
110 120 130 140 150
IDAKLTTEEV IKELAQIAGR PTEDEDEKEK VADEDDVDNE EAALLHEEAT
160 170 180 190 200
MTIEELLTRY GQNCHKGPPH SKSGGGTGEE PGSQGLNGEA GPEDSTRETP
210 220 230 240 250
SQENGPTAKA YTGFSSNSER GTEAGQVGEP GIPTGEAGPS CSSASDKLPR
260 270 280 290 300
VAKSKFFEDS EDESDEAEEE EEDSEECSEE EDGYSSEEAE NEEDEDDTEE
310 320 330 340 350
AEEDDEEEEE EMMVPGMEGK EEPGSDSGTT AVVALIRGKQ LIVANAGDSR
360 370 380 390 400
CVVSEAGKAL DMSYDHKPED EVELARIKNA GGKVTMDGRV NGGLNLSRAI
410 420 430 440 450
GDHFYKRNKN LPPEEQMISA LPDIKVLTLT DDHEFMVIAC DGIWNVMSSQ
460 470 480 490 500
EVVDFIQSKI SQRDENGELR LLSSIVEELL DQCLAPDTSG DGTGCDNMTC
510 520 530 540
IIICFKPRNT AELQPESGKR KLEEVLSTEG AEENGNSDKK KKAKRD
Length:546
Mass (Da):59,272
Last modified:May 10, 2005 - v1
Checksum:i084C16F8252330D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT007454 mRNA. Translation: AAP36122.1.
AC074117 Genomic DNA. Translation: AAY14846.1.
CR457059 mRNA. Translation: CAG33340.1.
CH471053 Genomic DNA. Translation: EAX00582.1.
RefSeqiNP_817092.1. NM_177983.2.
UniGeneiHs.643951.

Genome annotation databases

GeneIDi5496.
KEGGihsa:5496.
UCSCiuc002rkl.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT007454 mRNA. Translation: AAP36122.1.
AC074117 Genomic DNA. Translation: AAY14846.1.
CR457059 mRNA. Translation: CAG33340.1.
CH471053 Genomic DNA. Translation: EAX00582.1.
RefSeqiNP_817092.1. NM_177983.2.
UniGeneiHs.643951.

3D structure databases

SMRiQ6IAU5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ6IAU5. 1 interactor.
MINTiMINT-4901945.
STRINGi9606.ENSP00000264714.

Proteomic databases

MaxQBiQ6IAU5.

Protocols and materials databases

DNASUi5496.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5496.
KEGGihsa:5496.
UCSCiuc002rkl.5. human.

Organism-specific databases

CTDi5496.
PharmGKBiPA33606.

Phylogenomic databases

eggNOGiKOG0699. Eukaryota.
COG0631. LUCA.
HOVERGENiHBG053647.
KOiK17499.
OMAiGWRNSQE.
OrthoDBiEOG091G0D0W.

Miscellaneous databases

ChiTaRSiPPM1G. human.
GenomeRNAii5496.

Gene expression databases

BgeeiENSG00000115241.

Family and domain databases

Gene3Di3.60.40.10. 2 hits.
InterProiView protein in InterPro
IPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiView protein in Pfam
PF00481. PP2C. 2 hits.
SMARTiView protein in SMART
SM00332. PP2Cc. 1 hit.
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiView protein in PROSITE
PS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6IAU5_HUMAN
AccessioniPrimary (citable) accession number: Q6IAU5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: June 7, 2017
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.