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Protein
Submitted name:

PPM1G protein

Gene

PPM1G

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Cofactori

Mg2+SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protein phosphataseUniRule annotationSAAS annotation
LigandMagnesiumSAAS annotation, Metal-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
PPM1G proteinImported
Submitted name:
Protein phosphatase 1G (Formerly 2C), magnesium-dependent, gamma isoformImported
Gene namesi
Name:PPM1GImported
ORF Names:hCG_21229Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000115241.10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33606

PTM / Processingi

Proteomic databases

MaxQBiQ6IAU5
PRIDEiQ6IAU5

Expressioni

Gene expression databases

BgeeiENSG00000115241
ExpressionAtlasiQ6IAU5 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiQ6IAU5, 1 interactor

Structurei

3D structure databases

SMRiQ6IAU5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 505PPM-type phosphataseInterPro annotationAdd BLAST480

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili257 – 280Sequence analysisAdd BLAST24
Coiled coili284 – 311Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the PP2C family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0699 Eukaryota
COG0631 LUCA
HOVERGENiHBG053647
KOiK17499
OMAiGWRNSQE
OrthoDBiEOG091G0D0W

Family and domain databases

CDDicd00143 PP2Cc, 2 hits
Gene3Di3.60.40.10, 2 hits
InterProiView protein in InterPro
IPR015655 PP2C
IPR000222 PP2C_BS
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 2 hits
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 2 hits
PROSITEiView protein in PROSITE
PS01032 PPM_1, 1 hit
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6IAU5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAYLSQPNT VKCSGDGVGA PRLPLPYGFS AMQGWRVSME DAHNCIPELD
60 70 80 90 100
SETAMFSVYD GHGGEEVALY CAKYLPDIIK DQKAYKEGKL QKALEDAFLA
110 120 130 140 150
IDAKLTTEEV IKELAQIAGR PTEDEDEKEK VADEDDVDNE EAALLHEEAT
160 170 180 190 200
MTIEELLTRY GQNCHKGPPH SKSGGGTGEE PGSQGLNGEA GPEDSTRETP
210 220 230 240 250
SQENGPTAKA YTGFSSNSER GTEAGQVGEP GIPTGEAGPS CSSASDKLPR
260 270 280 290 300
VAKSKFFEDS EDESDEAEEE EEDSEECSEE EDGYSSEEAE NEEDEDDTEE
310 320 330 340 350
AEEDDEEEEE EMMVPGMEGK EEPGSDSGTT AVVALIRGKQ LIVANAGDSR
360 370 380 390 400
CVVSEAGKAL DMSYDHKPED EVELARIKNA GGKVTMDGRV NGGLNLSRAI
410 420 430 440 450
GDHFYKRNKN LPPEEQMISA LPDIKVLTLT DDHEFMVIAC DGIWNVMSSQ
460 470 480 490 500
EVVDFIQSKI SQRDENGELR LLSSIVEELL DQCLAPDTSG DGTGCDNMTC
510 520 530 540
IIICFKPRNT AELQPESGKR KLEEVLSTEG AEENGNSDKK KKAKRD
Length:546
Mass (Da):59,272
Last modified:May 10, 2005 - v1
Checksum:i084C16F8252330D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT007454 mRNA Translation: AAP36122.1
AC074117 Genomic DNA Translation: AAY14846.1
CR457059 mRNA Translation: CAG33340.1
CH471053 Genomic DNA Translation: EAX00582.1
RefSeqiNP_817092.1, NM_177983.2
UniGeneiHs.643951

Genome annotation databases

GeneIDi5496
KEGGihsa:5496
UCSCiuc002rkl.5 human

Similar proteinsi

Entry informationi

Entry nameiQ6IAU5_HUMAN
AccessioniPrimary (citable) accession number: Q6IAU5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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