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Protein
Submitted name:

LYPLA1 protein

Gene

LYPLA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

BRENDAi3.1.1.5. 2681.

Protein family/group databases

ESTHERihuman-LYPLA1. LYsophospholipase_carboxylesterase.

Names & Taxonomyi

Protein namesi
Submitted name:
LYPLA1 proteinImported
Submitted name:
Lysophospholipase I, isoform CRA_aImported
Submitted name:
cDNA FLJ78542, highly similar to Homo sapiens lysophospholipase I (LYPLA1), mRNAImported
Submitted name:
cDNA, FLJ94339, Homo sapiens lysophospholipase I (LYPLA1), mRNAImported
Gene namesi
Name:LYPLA1Imported
ORF Names:hCG_1983522Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000120992.17.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA30499.

PTM / Processingi

Proteomic databases

MaxQBiQ6IAQ1.

Expressioni

Gene expression databases

BgeeiENSG00000120992.
ExpressionAtlasiQ6IAQ1. baseline and differential.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
GOLGA2Q083793EBI-10249913,EBI-618309

Protein-protein interaction databases

IntActiQ6IAQ1. 1 interactor.

Structurei

3D structure databases

SMRiQ6IAQ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 225Abhydrolase_2InterPro annotationAdd BLAST215

Phylogenomic databases

eggNOGiKOG2112. Eukaryota.
COG0400. LUCA.
HOVERGENiHBG052378.
KOiK06128.
OMAiSACPEEM.
OrthoDBiEOG091G080L.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiView protein in InterPro
IPR029058. AB_hydrolase.
IPR003140. PLipase/COase/thioEstase.
PfamiView protein in Pfam
PF02230. Abhydrolase_2. 1 hit.
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6IAQ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCGNNMSTPL PAIVPAARKA TAAVIFLHGL GDTGHGWAEA FAGIRSSHIK
60 70 80 90 100
YICPHAPVRP VTLNMNVAMP SWFDIIGLSP DSQEDESGIK QAAENIKALI
110 120 130 140 150
DQEVKNGIPS NRIILGGFSQ GGALSLYTAL TTQQKLAGVT ALSCWLPLRA
160 170 180 190 200
SFPQGPIGGA NRDISILQCH GDCDPLVPLM FGSLTVEKLK TLVNPANVTF
210 220 230
KTYEGMMHSS CQQEMMDVKQ FIDKLLPPID
Length:230
Mass (Da):24,670
Last modified:May 10, 2005 - v1
Checksum:i90C0522F765F1AC6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK289400 mRNA. Translation: BAF82089.1.
AK313739 mRNA. Translation: BAG36480.1.
CR457103 mRNA. Translation: CAG33384.1.
CH471068 Genomic DNA. Translation: EAW86742.1.
CH471068 Genomic DNA. Translation: EAW86744.1.
RefSeqiNP_006321.1. NM_006330.3.
UniGeneiHs.744046.

Genome annotation databases

GeneIDi10434.
KEGGihsa:10434.
UCSCiuc003xry.4. human.

Similar proteinsi

Entry informationi

Entry nameiQ6IAQ1_HUMAN
AccessioniPrimary (citable) accession number: Q6IAQ1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 27, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.