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Protein
Submitted name:

KCNE3 protein

Gene

KCNE3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
KCNE3 proteinImported
Submitted name:
Potassium voltage-gated channel subfamily E member 3Imported
Submitted name:
Potassium voltage-gated channel, Isk-related family, member 3Imported
Submitted name:
Putative uncharacterized protein DKFZp781H21101Imported
Submitted name:
cDNA, FLJ92142, Homo sapiens potassium voltage-gated channel, Isk-related family,member 3 (KCNE3), mRNAImported
Gene namesi
Name:KCNE3Imported
Synonyms:DKFZp781H21101Imported
ORF Names:hCG_27327Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei58 – 79HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA393.

Expressioni

Gene expression databases

BgeeiENSG00000175538.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000310557.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IZ1X. Eukaryota.
ENOG410XU3Y. LUCA.
HOVERGENiHBG052228.
KOiK04897.
OMAiGPGPDNQ.
OrthoDBiEOG091G0Z41.

Family and domain databases

InterProiIPR000369. K_chnl_KCNE.
IPR005426. K_chnl_volt-dep_bsu_KCNE3.
[Graphical view]
PANTHERiPTHR15282:SF6. PTHR15282:SF6. 1 hit.
PfamiPF02060. ISK_Channel. 1 hit.
[Graphical view]
PRINTSiPR01606. KCNE3CHANNEL.
PR00168. KCNECHANNEL.

Sequencei

Sequence statusi: Complete.

Q6IAE6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METTNGTETW YESLHAVLKA LNATLHSNLL CRPGPGLGPD NQTEERRASL
60 70 80 90 100
PGRDDNSYMY ILFVMFLFAV TVGSLILGYT RSRKVDKRSD PYHVYIKNRV

SMI
Length:103
Mass (Da):11,710
Last modified:May 10, 2005 - v1
Checksum:i5235385E8D08BF10
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC110612 mRNA. Translation: AAI10613.1.
BC113743 mRNA. Translation: AAI13744.1.
DQ784805 Genomic DNA. Translation: ABQ01240.1.
AK311876 mRNA. Translation: BAG34817.1.
CR457209 mRNA. Translation: CAG33490.1.
CR936625 mRNA. Translation: CAI56768.1.
CH471076 Genomic DNA. Translation: EAW74938.1.
RefSeqiNP_005463.1. NM_005472.4.
XP_016872536.1. XM_017017047.1.
XP_016872537.1. XM_017017048.1.
XP_016872538.1. XM_017017049.1.
XP_016872539.1. XM_017017050.1.
XP_016872540.1. XM_017017051.1.
XP_016872541.1. XM_017017052.1.
UniGeneiHs.523899.

Genome annotation databases

GeneIDi10008.
KEGGihsa:10008.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC110612 mRNA. Translation: AAI10613.1.
BC113743 mRNA. Translation: AAI13744.1.
DQ784805 Genomic DNA. Translation: ABQ01240.1.
AK311876 mRNA. Translation: BAG34817.1.
CR457209 mRNA. Translation: CAG33490.1.
CR936625 mRNA. Translation: CAI56768.1.
CH471076 Genomic DNA. Translation: EAW74938.1.
RefSeqiNP_005463.1. NM_005472.4.
XP_016872536.1. XM_017017047.1.
XP_016872537.1. XM_017017048.1.
XP_016872538.1. XM_017017049.1.
XP_016872539.1. XM_017017050.1.
XP_016872540.1. XM_017017051.1.
XP_016872541.1. XM_017017052.1.
UniGeneiHs.523899.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000310557.

Protocols and materials databases

DNASUi10008.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10008.
KEGGihsa:10008.

Organism-specific databases

CTDi10008.
PharmGKBiPA393.

Phylogenomic databases

eggNOGiENOG410IZ1X. Eukaryota.
ENOG410XU3Y. LUCA.
HOVERGENiHBG052228.
KOiK04897.
OMAiGPGPDNQ.
OrthoDBiEOG091G0Z41.

Miscellaneous databases

ChiTaRSiKCNE3. human.
GenomeRNAii10008.

Gene expression databases

BgeeiENSG00000175538.

Family and domain databases

InterProiIPR000369. K_chnl_KCNE.
IPR005426. K_chnl_volt-dep_bsu_KCNE3.
[Graphical view]
PANTHERiPTHR15282:SF6. PTHR15282:SF6. 1 hit.
PfamiPF02060. ISK_Channel. 1 hit.
[Graphical view]
PRINTSiPR01606. KCNE3CHANNEL.
PR00168. KCNECHANNEL.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6IAE6_HUMAN
AccessioniPrimary (citable) accession number: Q6IAE6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 2, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.