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Protein
Submitted name:

CDKN1B protein

Gene

CDKN1B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
CDKN1B proteinImported
Submitted name:
Cyclin-dependent kinase inhibitor 1BImported
Submitted name:
Cyclin-dependent kinase inhibitor 1B (P27, Kip1), isoform CRA_aImported
Submitted name:
cDNA, FLJ92816, Homo sapiens cyclin-dependent kinase inhibitor 1B (p27, Kip1)(CDKN1B), mRNAImported
Gene namesi
Name:CDKN1BImported
ORF Names:hCG_27692Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA105.

PTM / Processingi

Proteomic databases

MaxQBiQ6I9V6.

Expressioni

Gene expression databases

BgeeiENSG00000111276.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000228872.

Structurei

3D structure databases

SMRiQ6I9V6. Positions 25-93.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4743. Eukaryota.
ENOG410XXN5. LUCA.
HOVERGENiHBG073988.
KOiK06624.
OMAiYPKPSAC.
PhylomeDBiQ6I9V6.

Family and domain databases

InterProiIPR003175. CDI.
IPR029843. CDKN1B.
[Graphical view]
PANTHERiPTHR10265. PTHR10265. 1 hit.
PTHR10265:SF9. PTHR10265:SF9. 1 hit.
PfamiPF02234. CDI. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6I9V6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNVRVSNGS PSLERMDARQ AEHPKPSACR NLFGPVDHEE LTRDLEKHCR
60 70 80 90 100
DMEEASQRKW NFDFQNHKPL EGKYEWQEVE KGSLPEFYYR PPRPPKGACK
110 120 130 140 150
VPAQESQDVS GSRPAAPLIG APANSEDTHL VDPKTDPSDS QTGLAEQCAG
160 170 180 190
IRKRPATDDS STQNKRANRT EENVSDGSPN AGSVEQTPKK PGLRRRQT
Length:198
Mass (Da):22,073
Last modified:May 10, 2005 - v1
Checksum:i1118D58901CDF3FC
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei198 – 1981Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312461 mRNA. Translation: BAG35368.1.
AB451291 mRNA. Translation: BAG70105.1.
AB451423 mRNA. Translation: BAG70237.1.
CR457399 mRNA. Translation: CAG33680.1.
CH471094 Genomic DNA. Translation: EAW96275.1.
RefSeqiNP_004055.1. NM_004064.4.
UniGeneiHs.238990.

Genome annotation databases

GeneIDi1027.
KEGGihsa:1027.
UCSCiuc001rat.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312461 mRNA. Translation: BAG35368.1.
AB451291 mRNA. Translation: BAG70105.1.
AB451423 mRNA. Translation: BAG70237.1.
CR457399 mRNA. Translation: CAG33680.1.
CH471094 Genomic DNA. Translation: EAW96275.1.
RefSeqiNP_004055.1. NM_004064.4.
UniGeneiHs.238990.

3D structure databases

SMRiQ6I9V6. Positions 25-93.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000228872.

Proteomic databases

MaxQBiQ6I9V6.

Protocols and materials databases

DNASUi1027.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1027.
KEGGihsa:1027.
UCSCiuc001rat.3. human.

Organism-specific databases

CTDi1027.
PharmGKBiPA105.

Phylogenomic databases

eggNOGiKOG4743. Eukaryota.
ENOG410XXN5. LUCA.
HOVERGENiHBG073988.
KOiK06624.
OMAiYPKPSAC.
PhylomeDBiQ6I9V6.

Miscellaneous databases

ChiTaRSiCDKN1B. human.
GenomeRNAii1027.

Gene expression databases

BgeeiENSG00000111276.

Family and domain databases

InterProiIPR003175. CDI.
IPR029843. CDKN1B.
[Graphical view]
PANTHERiPTHR10265. PTHR10265. 1 hit.
PTHR10265:SF9. PTHR10265:SF9. 1 hit.
PfamiPF02234. CDI. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6I9V6_HUMAN
AccessioniPrimary (citable) accession number: Q6I9V6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 7, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.