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Protein
Submitted name:

SLC25A6 protein

Gene

SLC25A6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Biological processTransportUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
SLC25A6 proteinImported
Submitted name:
Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 6Imported
Submitted name:
cDNA, FLJ92654, highly similar to Homo sapiens solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 (SLC25A6), mRNAImported
Gene namesi
Name:SLC25A6Imported
ORF Names:hCG_1746794Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000169100.13

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei173 – 191HelicalSequence analysisAdd BLAST19
Transmembranei211 – 231HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35868

PTM / Processingi

Proteomic databases

MaxQBiQ6I9V5
PRIDEiQ6I9V5

Expressioni

Gene expression databases

BgeeiENSG00000169100
ExpressionAtlasiQ6I9V5 baseline and differential

Structurei

3D structure databases

SMRiQ6I9V5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati6 – 98SolcarPROSITE-ProRule annotationAdd BLAST93
Repeati111 – 201SolcarPROSITE-ProRule annotationAdd BLAST91
Repeati212 – 297SolcarPROSITE-ProRule annotationAdd BLAST86

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0749 Eukaryota
ENOG410XNW0 LUCA
HOVERGENiHBG108348
KOiK05863
OMAiNGKRQFK
OrthoDBiEOG091G0ULB

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR002113 Aden_trnslctor
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
PRINTSiPR00927 ADPTRNSLCASE
PR00926 MITOCARRIER
SUPFAMiSSF103506 SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

Q6I9V5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEQAISFAK DFLAGGIAAA ISKTAVAPIE RVKLLLQVQH ASKQIAADKQ
60 70 80 90 100
YKGIVDCIVR IPKEQGVLSF WRGNLANVIR YFPTQALNFA FKDKYKQIFL
110 120 130 140 150
GGVDKHTQFW RYFAGNLASG GAAGATSLCF VYPLDFARTR LAADVGKSGT
160 170 180 190 200
EREFRGLGDC LVKITKSDGI RGLYQGFSVS VQGIIIYRAA YFGVYDTAKG
210 220 230 240 250
MLPDPKNTHI VVSWMIAQTV TAVAGVVSYP FDTVRRRMMM QSGRKGADIM
260 270 280 290
YTGTVDCWRK IFRDEGGKAF FKGAWSNVLR GMGGAFVLVL YDELKKVI
Length:298
Mass (Da):32,866
Last modified:May 10, 2005 - v1
Checksum:i18534E9F0E49672F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312336 mRNA Translation: BAG35257.1
CR457400 mRNA Translation: CAG33681.1
CH471074 Genomic DNA Translation: EAW98680.1
RefSeqiNP_001627.2, NM_001636.3
UniGeneiHs.350927
Hs.680626

Genome annotation databases

GeneIDi293
KEGGihsa:293
UCSCiuc004cpt.4 human

Similar proteinsi

Entry informationi

Entry nameiQ6I9V5_HUMAN
AccessioniPrimary (citable) accession number: Q6I9V5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health