Reviewed, UniProtKB/Swiss-Prot Q6I5Y0 (CDKC1_ORYSJ)

Names and origin

Protein names

Recommended name:
    Cyclin-dependent kinase C-1
      Short name=CDKC;1
    EC=2.7.11.22
    EC=2.7.11.23

Gene names

Name:	CDKC-1
Ordered Locus Names:	Os05g0389700, LOC_Os05g32360
ORF Names:	OJ1562_H01.5

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	519 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.
Induction	By auxin. Down-regulated by cytokinin. Ref.5
Sequence similarities	Belongs to the Ser/Thr protein kinase family. CDC2/CDKX subfamily. Contains 1 protein kinase domain.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase Transferase
PTM	Phosphoprotein
Gene Ontology (GO)
Biological process	protein amino acid phosphorylation Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW RNA polymerase II carboxy-terminal domain kinase activity Inferred from electronic annotation. Source: EC cyclin-dependent protein kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 519	519	Cyclin-dependent kinase C-1		PRO_0000296100
Regions
	Domain	25 – 325	301	Protein kinase
	Nucleotide binding	31 – 39	9	ATP By similarity
Sites
	Active site	164	1	Proton acceptor By similarity
	Binding site	54	1	ATP By similarity
Amino acid modifications
	Modified residue	35	1	Phosphothreonine By similarity
	Modified residue	36	1	Phosphotyrosine By similarity
	Modified residue	198	1	Phosphothreonine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6I5Y0-1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 8CF0E99557E0E05C	FASTA	519	57,451
	10 20 30 40 50 60 MAVAAPGQLN LDESPSWGSR SVDCFEKLEQ IGEGTYGQVY MARETETQEI VALKKIRMDN 70 80 90 100 110 120 EREGFPITAI REIKILKKLH HQNVIQLKEI VTSPGPERDE QGKPIHGNKY KGSIYMVFEY 130 140 150 160 170 180 MDHDLTGLAD RPGMRFTVPQ IKCYMKQLLT GLHYCHINQV LHRDIKGSNL LIDNEGNLKL 190 200 210 220 230 240 ADFGLARSFS NDHNGNLTNR VITLWYRPPE LLLGSTKYGP AVDMWSVGCI FAELLNGKPI 250 260 270 280 290 300 LPGKNEPEQL SKIFDVCGTP DESNWPGVTK MPWYNNFKPP RQLKRRVKEY FKHFDRLALD 310 320 330 340 350 360 LLEKMLTLDP AQRISAQDAL DAEYFWSDPL PCDPKSLPKY ESSHEFQTKK KRQQMRQADE 370 380 390 400 410 420 AAKRQKTQHP QPHGRLPPIQ QTGQPHPQIR PGQPMNNPHA PMAAGPGHHY AKPRGPGGSS 430 440 450 460 470 480 RYPQGGNQGG GYPNRGGQGG GGSYGNAPYP QQGRGPPPPY PGSGMAGTGG PRGGVGGGYG 490 500 510 GGSNYPQQGG PYGPSGPGRG SNYPQQGGSR NQQQYGNWQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A fine physical map of the rice chromosome 5." Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J., Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F., Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y. Mol. Genet. Genomics 274:337-345(2005) [PubMed: 16261349] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana." The rice annotation project (RAP) Genome Res. 17:175-183(2007) [PubMed: 17210932] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed: 12869764] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[5]	"Genome-wide identification and expression analysis of rice cell cycle genes." Guo J., Song J., Wang F., Zhang X.S. Plant Mol. Biol. 64:349-360(2007) [PubMed: 17443292] [Abstract] Cited for: INDUCTION, GENE FAMILY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AC105773 Genomic DNA. Translation: AAT47442.1. AP008211 Genomic DNA. Translation: BAF17350.1. AK073808 mRNA. No translation available.
RefSeq	NP_001055436.1.
UniGene	Os.4626
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4338674.
GenomeReviews	Gene locus CDKC-1 in contig AP008211_GR.
KEGG	osa:4338674.
Organism-specific databases
Gramene	Q6I5Y0.
Family and domain databases
InterPro	IPR000719. Prot_kinase_core. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_pkinase-rel. IPR008271. Ser_thr_pkin_AS. IPR002290. Ser_thr_pkinase. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
ProDom	PD000001. Prot_kinase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CDKC1_ORYSJ

Accession

Primary (citable) accession number: Q6I5Y0

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 24, 2007
Last sequence update:	July 19, 2004
Last modified:	September 22, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)